| Full name: RNA guanylyltransferase and 5'-phosphatase | Alias Symbol: HCE|HCE1|hCAP | ||
| Type: protein-coding gene | Cytoband: 6q15 | ||
| Entrez ID: 8732 | HGNC ID: HGNC:10073 | Ensembl Gene: ENSG00000111880 | OMIM ID: 603512 |
Expression of RNGTT:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNGTT | 8732 | 204208_at | -0.2442 | 0.3994 | |
| GSE20347 | RNGTT | 8732 | 211387_x_at | 0.2658 | 0.1328 | |
| GSE23400 | RNGTT | 8732 | 211387_x_at | 0.0419 | 0.3957 | |
| GSE26886 | RNGTT | 8732 | 204208_at | -0.7164 | 0.0002 | |
| GSE29001 | RNGTT | 8732 | 204208_at | -0.1538 | 0.5342 | |
| GSE38129 | RNGTT | 8732 | 204208_at | -0.0735 | 0.4786 | |
| GSE45670 | RNGTT | 8732 | 204208_at | -0.1679 | 0.1105 | |
| GSE53622 | RNGTT | 8732 | 38065 | -0.1759 | 0.0377 | |
| GSE53624 | RNGTT | 8732 | 38065 | -0.2325 | 0.0135 | |
| GSE63941 | RNGTT | 8732 | 204207_s_at | 1.6953 | 0.0001 | |
| GSE77861 | RNGTT | 8732 | 211387_x_at | 0.3805 | 0.2330 | |
| GSE97050 | RNGTT | 8732 | A_23_P325075 | 0.0148 | 0.9490 | |
| SRP007169 | RNGTT | 8732 | RNAseq | 0.0277 | 0.9429 | |
| SRP008496 | RNGTT | 8732 | RNAseq | -0.0777 | 0.7852 | |
| SRP064894 | RNGTT | 8732 | RNAseq | -0.1552 | 0.4217 | |
| SRP133303 | RNGTT | 8732 | RNAseq | 0.1115 | 0.4825 | |
| SRP159526 | RNGTT | 8732 | RNAseq | -0.3023 | 0.1694 | |
| SRP193095 | RNGTT | 8732 | RNAseq | -0.2804 | 0.0034 | |
| SRP219564 | RNGTT | 8732 | RNAseq | -0.3966 | 0.3437 | |
| TCGA | RNGTT | 8732 | RNAseq | 0.1095 | 0.0452 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by RNGTT expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RNGTT:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNGTT | 8732 | 1 | 4 | 25 | |
| GSE20123 | RNGTT | 8732 | 1 | 3 | 26 | |
| GSE43470 | RNGTT | 8732 | 3 | 1 | 39 | |
| GSE46452 | RNGTT | 8732 | 2 | 11 | 46 | |
| GSE47630 | RNGTT | 8732 | 8 | 6 | 26 | |
| GSE54993 | RNGTT | 8732 | 3 | 2 | 65 | |
| GSE54994 | RNGTT | 8732 | 8 | 8 | 37 | |
| GSE60625 | RNGTT | 8732 | 0 | 1 | 10 | |
| GSE74703 | RNGTT | 8732 | 3 | 1 | 32 | |
| GSE74704 | RNGTT | 8732 | 0 | 2 | 18 | |
| TCGA | RNGTT | 8732 | 7 | 22 | 67 |
Total number of gains: 36; Total number of losses: 61; Total Number of normals: 391.
Somatic mutations of RNGTT:
Generating mutation plots.
Highly correlated genes for RNGTT:
Showing top 20/224 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNGTT | EAF1 | 0.794461 | 3 | 0 | 3 |
| RNGTT | ITGA2 | 0.774455 | 3 | 0 | 3 |
| RNGTT | ZDHHC21 | 0.750334 | 3 | 0 | 3 |
| RNGTT | TAS2R19 | 0.746288 | 3 | 0 | 3 |
| RNGTT | CRLF3 | 0.738454 | 3 | 0 | 3 |
| RNGTT | PSMA4 | 0.736713 | 3 | 0 | 3 |
| RNGTT | NIPSNAP3A | 0.73411 | 3 | 0 | 3 |
| RNGTT | DECR1 | 0.729083 | 3 | 0 | 3 |
| RNGTT | MPZL3 | 0.724706 | 4 | 0 | 4 |
| RNGTT | UBQLN1 | 0.720447 | 3 | 0 | 3 |
| RNGTT | DPH3 | 0.719842 | 3 | 0 | 3 |
| RNGTT | SLC12A6 | 0.719194 | 3 | 0 | 3 |
| RNGTT | RNFT1 | 0.718837 | 3 | 0 | 3 |
| RNGTT | AKIRIN2 | 0.715368 | 4 | 0 | 4 |
| RNGTT | DNAJC1 | 0.711904 | 3 | 0 | 3 |
| RNGTT | RAB27A | 0.710822 | 4 | 0 | 4 |
| RNGTT | CSNK1A1 | 0.708933 | 4 | 0 | 3 |
| RNGTT | CRK | 0.708303 | 5 | 0 | 5 |
| RNGTT | TBRG1 | 0.700366 | 3 | 0 | 3 |
| RNGTT | DNAJC7 | 0.700316 | 4 | 0 | 4 |
For details and further investigation, click here
