| Full name: CAP-Gly domain containing linker protein 1 | Alias Symbol: CYLN1|CLIP170|CLIP|CLIP-170 | ||
| Type: protein-coding gene | Cytoband: 12q24.31 | ||
| Entrez ID: 6249 | HGNC ID: HGNC:10461 | Ensembl Gene: ENSG00000130779 | OMIM ID: 179838 |
| Drug and gene relationship at DGIdb | |||
Expression of CLIP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CLIP1 | 6249 | 201975_at | -0.7483 | 0.0869 | |
| GSE20347 | CLIP1 | 6249 | 201975_at | -1.1686 | 0.0000 | |
| GSE23400 | CLIP1 | 6249 | 201975_at | -0.7295 | 0.0000 | |
| GSE26886 | CLIP1 | 6249 | 201975_at | -1.1162 | 0.0000 | |
| GSE29001 | CLIP1 | 6249 | 201975_at | -0.7037 | 0.0174 | |
| GSE38129 | CLIP1 | 6249 | 201975_at | -0.9874 | 0.0000 | |
| GSE45670 | CLIP1 | 6249 | 201975_at | -0.1626 | 0.4500 | |
| GSE53622 | CLIP1 | 6249 | 24115 | -1.0495 | 0.0000 | |
| GSE53624 | CLIP1 | 6249 | 24115 | -1.1212 | 0.0000 | |
| GSE63941 | CLIP1 | 6249 | 201975_at | -1.1148 | 0.0140 | |
| GSE77861 | CLIP1 | 6249 | 201975_at | -0.5872 | 0.0293 | |
| GSE97050 | CLIP1 | 6249 | A_23_P25003 | -0.7242 | 0.0781 | |
| SRP007169 | CLIP1 | 6249 | RNAseq | -1.1263 | 0.0011 | |
| SRP008496 | CLIP1 | 6249 | RNAseq | -1.1565 | 0.0000 | |
| SRP064894 | CLIP1 | 6249 | RNAseq | -1.3679 | 0.0000 | |
| SRP133303 | CLIP1 | 6249 | RNAseq | -0.6662 | 0.0000 | |
| SRP159526 | CLIP1 | 6249 | RNAseq | -1.3366 | 0.0000 | |
| SRP193095 | CLIP1 | 6249 | RNAseq | -0.8180 | 0.0000 | |
| SRP219564 | CLIP1 | 6249 | RNAseq | -1.4613 | 0.0000 | |
| TCGA | CLIP1 | 6249 | RNAseq | 0.0235 | 0.6970 |
Upregulated datasets: 0; Downregulated datasets: 10.
Survival by CLIP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CLIP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CLIP1 | 6249 | 5 | 4 | 21 | |
| GSE20123 | CLIP1 | 6249 | 5 | 4 | 21 | |
| GSE43470 | CLIP1 | 6249 | 2 | 2 | 39 | |
| GSE46452 | CLIP1 | 6249 | 9 | 1 | 49 | |
| GSE47630 | CLIP1 | 6249 | 9 | 3 | 28 | |
| GSE54993 | CLIP1 | 6249 | 0 | 5 | 65 | |
| GSE54994 | CLIP1 | 6249 | 5 | 7 | 41 | |
| GSE60625 | CLIP1 | 6249 | 0 | 0 | 11 | |
| GSE74703 | CLIP1 | 6249 | 2 | 1 | 33 | |
| GSE74704 | CLIP1 | 6249 | 4 | 2 | 14 | |
| TCGA | CLIP1 | 6249 | 21 | 10 | 65 |
Total number of gains: 62; Total number of losses: 39; Total Number of normals: 387.
Somatic mutations of CLIP1:
Generating mutation plots.
Highly correlated genes for CLIP1:
Showing top 20/1553 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CLIP1 | CCNYL1 | 0.798665 | 5 | 0 | 5 |
| CLIP1 | GGA3 | 0.790397 | 3 | 0 | 3 |
| CLIP1 | CPEB4 | 0.784482 | 8 | 0 | 8 |
| CLIP1 | CAST | 0.78441 | 11 | 0 | 11 |
| CLIP1 | RASSF3 | 0.781609 | 3 | 0 | 3 |
| CLIP1 | TMOD3 | 0.780358 | 10 | 0 | 10 |
| CLIP1 | RAB11A | 0.771927 | 11 | 0 | 11 |
| CLIP1 | PPM1L | 0.770494 | 3 | 0 | 3 |
| CLIP1 | RNF141 | 0.766253 | 11 | 0 | 11 |
| CLIP1 | DOCK9 | 0.759978 | 11 | 0 | 11 |
| CLIP1 | TJP1 | 0.758417 | 12 | 0 | 11 |
| CLIP1 | PDCD6IP | 0.755526 | 12 | 0 | 11 |
| CLIP1 | PXMP2 | 0.755376 | 3 | 0 | 3 |
| CLIP1 | CYSRT1 | 0.752542 | 6 | 0 | 6 |
| CLIP1 | KAT2B | 0.749426 | 13 | 0 | 12 |
| CLIP1 | CA13 | 0.746617 | 3 | 0 | 3 |
| CLIP1 | KRT78 | 0.744769 | 6 | 0 | 6 |
| CLIP1 | CWH43 | 0.74111 | 10 | 0 | 10 |
| CLIP1 | CPEB2 | 0.740832 | 8 | 0 | 8 |
| CLIP1 | ITSN2 | 0.740086 | 12 | 0 | 11 |
For details and further investigation, click here
