| Full name: cytochrome c oxidase assembly factor COX19 | Alias Symbol: MGC104475 | ||
| Type: protein-coding gene | Cytoband: 7p22.3 | ||
| Entrez ID: 90639 | HGNC ID: HGNC:28074 | Ensembl Gene: ENSG00000240230 | OMIM ID: 610429 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of COX19:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COX19 | 90639 | 231831_at | 0.1113 | 0.5980 | |
| GSE26886 | COX19 | 90639 | 231831_at | -0.2105 | 0.1670 | |
| GSE45670 | COX19 | 90639 | 231831_at | 0.1520 | 0.0502 | |
| GSE63941 | COX19 | 90639 | 231831_at | 0.8901 | 0.0146 | |
| GSE77861 | COX19 | 90639 | 231831_at | -0.0096 | 0.9611 | |
| GSE97050 | COX19 | 90639 | A_32_P9468 | -0.2311 | 0.3304 | |
| SRP007169 | COX19 | 90639 | RNAseq | 0.2574 | 0.5549 | |
| SRP008496 | COX19 | 90639 | RNAseq | 0.6448 | 0.0444 | |
| SRP064894 | COX19 | 90639 | RNAseq | 0.6744 | 0.0008 | |
| SRP133303 | COX19 | 90639 | RNAseq | 0.2883 | 0.0466 | |
| SRP159526 | COX19 | 90639 | RNAseq | 0.4913 | 0.1667 | |
| SRP193095 | COX19 | 90639 | RNAseq | 0.1280 | 0.1761 | |
| SRP219564 | COX19 | 90639 | RNAseq | 0.3343 | 0.2909 | |
| TCGA | COX19 | 90639 | RNAseq | 0.0184 | 0.7524 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by COX19 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of COX19:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COX19 | 90639 | 14 | 0 | 16 | |
| GSE20123 | COX19 | 90639 | 14 | 0 | 16 | |
| GSE43470 | COX19 | 90639 | 6 | 2 | 35 | |
| GSE46452 | COX19 | 90639 | 13 | 1 | 45 | |
| GSE47630 | COX19 | 90639 | 12 | 1 | 27 | |
| GSE54993 | COX19 | 90639 | 3 | 10 | 57 | |
| GSE54994 | COX19 | 90639 | 20 | 3 | 30 | |
| GSE60625 | COX19 | 90639 | 0 | 0 | 11 | |
| GSE74703 | COX19 | 90639 | 6 | 1 | 29 | |
| GSE74704 | COX19 | 90639 | 9 | 0 | 11 | |
| TCGA | COX19 | 90639 | 56 | 6 | 34 |
Total number of gains: 153; Total number of losses: 24; Total Number of normals: 311.
Somatic mutations of COX19:
Generating mutation plots.
Highly correlated genes for COX19:
Showing top 20/178 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COX19 | DNHD1 | 0.729126 | 3 | 0 | 3 |
| COX19 | SBF1 | 0.719063 | 3 | 0 | 3 |
| COX19 | PTPN3 | 0.715531 | 3 | 0 | 3 |
| COX19 | SEMA4A | 0.709082 | 3 | 0 | 3 |
| COX19 | CMTM4 | 0.707744 | 3 | 0 | 3 |
| COX19 | MAP3K5 | 0.686509 | 3 | 0 | 3 |
| COX19 | INO80B | 0.678155 | 3 | 0 | 3 |
| COX19 | GALNT3 | 0.6625 | 4 | 0 | 3 |
| COX19 | IFNGR2 | 0.661832 | 3 | 0 | 3 |
| COX19 | LCAT | 0.660484 | 3 | 0 | 3 |
| COX19 | BPHL | 0.660271 | 3 | 0 | 3 |
| COX19 | NOTCH3 | 0.657046 | 3 | 0 | 3 |
| COX19 | SSNA1 | 0.65441 | 3 | 0 | 3 |
| COX19 | MAP2K7 | 0.653622 | 4 | 0 | 4 |
| COX19 | PTPRF | 0.652049 | 4 | 0 | 3 |
| COX19 | THAP6 | 0.650608 | 3 | 0 | 3 |
| COX19 | COL11A2 | 0.650446 | 3 | 0 | 3 |
| COX19 | ZNF839 | 0.650338 | 3 | 0 | 3 |
| COX19 | TRPC4 | 0.649187 | 4 | 0 | 3 |
| COX19 | CSF2RA | 0.649147 | 3 | 0 | 3 |
For details and further investigation, click here
