| Full name: RNA polymerase III subunit D | Alias Symbol: TSBN51|RPC4 | ||
| Type: protein-coding gene | Cytoband: 8p21.3 | ||
| Entrez ID: 661 | HGNC ID: HGNC:1080 | Ensembl Gene: ENSG00000168495 | OMIM ID: 187280 |
| Drug and gene relationship at DGIdb | |||
Expression of POLR3D:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | POLR3D | 661 | 208361_s_at | 0.5037 | 0.1557 | |
| GSE20347 | POLR3D | 661 | 208361_s_at | 0.4076 | 0.0034 | |
| GSE23400 | POLR3D | 661 | 208361_s_at | 0.3044 | 0.0000 | |
| GSE26886 | POLR3D | 661 | 208361_s_at | 0.3690 | 0.0124 | |
| GSE29001 | POLR3D | 661 | 208361_s_at | 0.4030 | 0.0505 | |
| GSE38129 | POLR3D | 661 | 208361_s_at | 0.3762 | 0.0008 | |
| GSE45670 | POLR3D | 661 | 208361_s_at | 0.5731 | 0.0000 | |
| GSE53622 | POLR3D | 661 | 164795 | 0.4817 | 0.0000 | |
| GSE53624 | POLR3D | 661 | 95542 | -0.6538 | 0.0000 | |
| GSE63941 | POLR3D | 661 | 208361_s_at | -0.1041 | 0.8617 | |
| GSE77861 | POLR3D | 661 | 208361_s_at | 0.0610 | 0.7430 | |
| GSE97050 | POLR3D | 661 | A_23_P84565 | 0.1887 | 0.4278 | |
| SRP007169 | POLR3D | 661 | RNAseq | 0.6424 | 0.1190 | |
| SRP008496 | POLR3D | 661 | RNAseq | 1.0308 | 0.0006 | |
| SRP064894 | POLR3D | 661 | RNAseq | 0.3411 | 0.0185 | |
| SRP133303 | POLR3D | 661 | RNAseq | 0.1908 | 0.2586 | |
| SRP159526 | POLR3D | 661 | RNAseq | 0.2729 | 0.3401 | |
| SRP193095 | POLR3D | 661 | RNAseq | 0.3581 | 0.0006 | |
| SRP219564 | POLR3D | 661 | RNAseq | 0.3227 | 0.2576 | |
| TCGA | POLR3D | 661 | RNAseq | 0.0574 | 0.3534 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by POLR3D expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of POLR3D:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | POLR3D | 661 | 4 | 10 | 16 | |
| GSE20123 | POLR3D | 661 | 4 | 10 | 16 | |
| GSE43470 | POLR3D | 661 | 4 | 9 | 30 | |
| GSE46452 | POLR3D | 661 | 13 | 13 | 33 | |
| GSE47630 | POLR3D | 661 | 10 | 8 | 22 | |
| GSE54993 | POLR3D | 661 | 2 | 14 | 54 | |
| GSE54994 | POLR3D | 661 | 9 | 17 | 27 | |
| GSE60625 | POLR3D | 661 | 3 | 0 | 8 | |
| GSE74703 | POLR3D | 661 | 4 | 7 | 25 | |
| GSE74704 | POLR3D | 661 | 3 | 7 | 10 | |
| TCGA | POLR3D | 661 | 14 | 43 | 39 |
Total number of gains: 70; Total number of losses: 138; Total Number of normals: 280.
Somatic mutations of POLR3D:
Generating mutation plots.
Highly correlated genes for POLR3D:
Showing top 20/404 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| POLR3D | ZCCHC3 | 0.825533 | 3 | 0 | 3 |
| POLR3D | FAM168A | 0.799202 | 3 | 0 | 3 |
| POLR3D | SH2D3C | 0.767713 | 3 | 0 | 3 |
| POLR3D | SLC7A6OS | 0.766194 | 4 | 0 | 4 |
| POLR3D | CPLX1 | 0.758101 | 3 | 0 | 3 |
| POLR3D | CCNK | 0.740718 | 3 | 0 | 3 |
| POLR3D | C8orf76 | 0.736388 | 3 | 0 | 3 |
| POLR3D | TERF2 | 0.726368 | 3 | 0 | 3 |
| POLR3D | LNP1 | 0.72579 | 3 | 0 | 3 |
| POLR3D | IL1B | 0.72139 | 3 | 0 | 3 |
| POLR3D | CASC4 | 0.720784 | 3 | 0 | 3 |
| POLR3D | DNHD1 | 0.718541 | 3 | 0 | 3 |
| POLR3D | NIPA1 | 0.717609 | 4 | 0 | 4 |
| POLR3D | HAUS7 | 0.704508 | 3 | 0 | 3 |
| POLR3D | PSMB1 | 0.700531 | 3 | 0 | 3 |
| POLR3D | SNAPC2 | 0.698091 | 3 | 0 | 3 |
| POLR3D | FAM192A | 0.697145 | 4 | 0 | 3 |
| POLR3D | DMXL2 | 0.69248 | 4 | 0 | 4 |
| POLR3D | FLNB | 0.691948 | 3 | 0 | 3 |
| POLR3D | FAM199X | 0.688285 | 3 | 0 | 3 |
For details and further investigation, click here
