| Full name: downstream neighbor of SON | Alias Symbol: B17|C2TA|DKFZP434M035 | ||
| Type: protein-coding gene | Cytoband: 21q22.11 | ||
| Entrez ID: 29980 | HGNC ID: HGNC:2993 | Ensembl Gene: ENSG00000159147 | OMIM ID: 611428 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of DONSON:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DONSON | 29980 | 221677_s_at | 1.0121 | 0.0283 | |
| GSE20347 | DONSON | 29980 | 221677_s_at | 0.7029 | 0.0008 | |
| GSE23400 | DONSON | 29980 | 221677_s_at | 0.6963 | 0.0000 | |
| GSE26886 | DONSON | 29980 | 221677_s_at | 0.1577 | 0.6106 | |
| GSE29001 | DONSON | 29980 | 221677_s_at | 1.2495 | 0.0174 | |
| GSE38129 | DONSON | 29980 | 221677_s_at | 0.9381 | 0.0000 | |
| GSE45670 | DONSON | 29980 | 221677_s_at | 0.4217 | 0.0405 | |
| GSE53622 | DONSON | 29980 | 136343 | 0.7223 | 0.0000 | |
| GSE53624 | DONSON | 29980 | 136343 | 0.8976 | 0.0000 | |
| GSE63941 | DONSON | 29980 | 221677_s_at | 0.6319 | 0.3129 | |
| GSE77861 | DONSON | 29980 | 221677_s_at | 0.2231 | 0.5135 | |
| GSE97050 | DONSON | 29980 | A_23_P425502 | 0.3686 | 0.1657 | |
| SRP007169 | DONSON | 29980 | RNAseq | 0.9524 | 0.0316 | |
| SRP008496 | DONSON | 29980 | RNAseq | 0.7810 | 0.0119 | |
| SRP064894 | DONSON | 29980 | RNAseq | 1.1986 | 0.0000 | |
| SRP133303 | DONSON | 29980 | RNAseq | 0.4546 | 0.0000 | |
| SRP159526 | DONSON | 29980 | RNAseq | 0.5987 | 0.0003 | |
| SRP193095 | DONSON | 29980 | RNAseq | 0.4206 | 0.0001 | |
| SRP219564 | DONSON | 29980 | RNAseq | 0.2488 | 0.4827 | |
| TCGA | DONSON | 29980 | RNAseq | 0.4000 | 0.0000 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by DONSON expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DONSON:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DONSON | 29980 | 2 | 8 | 20 | |
| GSE20123 | DONSON | 29980 | 2 | 9 | 19 | |
| GSE43470 | DONSON | 29980 | 3 | 9 | 31 | |
| GSE46452 | DONSON | 29980 | 1 | 21 | 37 | |
| GSE47630 | DONSON | 29980 | 6 | 17 | 17 | |
| GSE54993 | DONSON | 29980 | 9 | 1 | 60 | |
| GSE54994 | DONSON | 29980 | 1 | 9 | 43 | |
| GSE60625 | DONSON | 29980 | 0 | 0 | 11 | |
| GSE74703 | DONSON | 29980 | 3 | 6 | 27 | |
| GSE74704 | DONSON | 29980 | 1 | 4 | 15 | |
| TCGA | DONSON | 29980 | 9 | 35 | 52 |
Total number of gains: 37; Total number of losses: 119; Total Number of normals: 332.
Somatic mutations of DONSON:
Generating mutation plots.
Highly correlated genes for DONSON:
Showing top 20/1564 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DONSON | COMMD7 | 0.817672 | 3 | 0 | 3 |
| DONSON | PHF5A | 0.800155 | 4 | 0 | 4 |
| DONSON | TRIM59 | 0.779277 | 4 | 0 | 4 |
| DONSON | MMS22L | 0.775501 | 3 | 0 | 3 |
| DONSON | PDCD2L | 0.753246 | 5 | 0 | 5 |
| DONSON | G2E3 | 0.749909 | 4 | 0 | 4 |
| DONSON | ZNF75A | 0.73518 | 3 | 0 | 3 |
| DONSON | GART | 0.725441 | 13 | 0 | 11 |
| DONSON | DPP9 | 0.724676 | 3 | 0 | 3 |
| DONSON | LSM4 | 0.721201 | 6 | 0 | 6 |
| DONSON | GMNN | 0.718403 | 12 | 0 | 12 |
| DONSON | ACTL6A | 0.7168 | 10 | 0 | 10 |
| DONSON | FAM89A | 0.711414 | 3 | 0 | 3 |
| DONSON | MIS18A | 0.710526 | 11 | 0 | 11 |
| DONSON | RIOK1 | 0.705631 | 5 | 0 | 4 |
| DONSON | ALMS1 | 0.701687 | 3 | 0 | 3 |
| DONSON | BORA | 0.701218 | 9 | 0 | 8 |
| DONSON | LAMTOR1 | 0.700189 | 3 | 0 | 3 |
| DONSON | RANBP6 | 0.699978 | 3 | 0 | 3 |
| DONSON | UCK2 | 0.699902 | 4 | 0 | 4 |
For details and further investigation, click here
