| Full name: ATPase family AAA domain containing 2 | Alias Symbol: PRO2000|DKFZp667N1320|MGC5254|MGC29843|CT137|ANCCA | ||
| Type: protein-coding gene | Cytoband: 8q24.13 | ||
| Entrez ID: 29028 | HGNC ID: HGNC:30123 | Ensembl Gene: ENSG00000156802 | OMIM ID: 611941 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of ATAD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATAD2 | 29028 | 218782_s_at | 1.8280 | 0.0086 | |
| GSE20347 | ATAD2 | 29028 | 218782_s_at | 2.0439 | 0.0000 | |
| GSE23400 | ATAD2 | 29028 | 218782_s_at | 1.3854 | 0.0000 | |
| GSE26886 | ATAD2 | 29028 | 222740_at | 0.4520 | 0.1432 | |
| GSE29001 | ATAD2 | 29028 | 218782_s_at | 2.0141 | 0.0005 | |
| GSE38129 | ATAD2 | 29028 | 218782_s_at | 2.3030 | 0.0000 | |
| GSE45670 | ATAD2 | 29028 | 222740_at | 1.2582 | 0.0000 | |
| GSE53622 | ATAD2 | 29028 | 90679 | 1.3840 | 0.0000 | |
| GSE53624 | ATAD2 | 29028 | 90679 | 1.7264 | 0.0000 | |
| GSE63941 | ATAD2 | 29028 | 222740_at | 2.5972 | 0.0003 | |
| GSE77861 | ATAD2 | 29028 | 222740_at | 1.1320 | 0.0086 | |
| GSE97050 | ATAD2 | 29028 | A_33_P3217238 | 1.1614 | 0.1049 | |
| SRP007169 | ATAD2 | 29028 | RNAseq | 1.8466 | 0.0004 | |
| SRP008496 | ATAD2 | 29028 | RNAseq | 1.9101 | 0.0000 | |
| SRP064894 | ATAD2 | 29028 | RNAseq | 1.5879 | 0.0000 | |
| SRP133303 | ATAD2 | 29028 | RNAseq | 1.4311 | 0.0000 | |
| SRP159526 | ATAD2 | 29028 | RNAseq | 1.2921 | 0.0001 | |
| SRP193095 | ATAD2 | 29028 | RNAseq | 1.1746 | 0.0000 | |
| SRP219564 | ATAD2 | 29028 | RNAseq | 1.2107 | 0.0172 | |
| TCGA | ATAD2 | 29028 | RNAseq | 0.4419 | 0.0000 |
Upregulated datasets: 17; Downregulated datasets: 0.
Survival by ATAD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ATAD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATAD2 | 29028 | 19 | 1 | 10 | |
| GSE20123 | ATAD2 | 29028 | 20 | 1 | 9 | |
| GSE43470 | ATAD2 | 29028 | 22 | 0 | 21 | |
| GSE46452 | ATAD2 | 29028 | 27 | 0 | 32 | |
| GSE47630 | ATAD2 | 29028 | 24 | 0 | 16 | |
| GSE54993 | ATAD2 | 29028 | 0 | 21 | 49 | |
| GSE54994 | ATAD2 | 29028 | 37 | 1 | 15 | |
| GSE60625 | ATAD2 | 29028 | 0 | 4 | 7 | |
| GSE74703 | ATAD2 | 29028 | 19 | 0 | 17 | |
| GSE74704 | ATAD2 | 29028 | 13 | 1 | 6 | |
| TCGA | ATAD2 | 29028 | 67 | 1 | 28 |
Total number of gains: 248; Total number of losses: 30; Total Number of normals: 210.
Somatic mutations of ATAD2:
Generating mutation plots.
Highly correlated genes for ATAD2:
Showing top 20/2127 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATAD2 | CDK1 | 0.841598 | 12 | 0 | 12 |
| ATAD2 | TPX2 | 0.839766 | 13 | 0 | 13 |
| ATAD2 | ASPM | 0.838301 | 12 | 0 | 12 |
| ATAD2 | BUB1 | 0.837463 | 11 | 0 | 11 |
| ATAD2 | NUF2 | 0.836512 | 9 | 0 | 8 |
| ATAD2 | STIL | 0.833518 | 12 | 0 | 12 |
| ATAD2 | CDKN3 | 0.826282 | 13 | 0 | 13 |
| ATAD2 | HJURP | 0.826212 | 12 | 0 | 12 |
| ATAD2 | ZNF707 | 0.821197 | 3 | 0 | 3 |
| ATAD2 | CEP55 | 0.8207 | 13 | 0 | 13 |
| ATAD2 | DEPDC1B | 0.820422 | 7 | 0 | 7 |
| ATAD2 | TTK | 0.820107 | 12 | 0 | 12 |
| ATAD2 | CENPF | 0.818704 | 12 | 0 | 12 |
| ATAD2 | KIF15 | 0.818463 | 12 | 0 | 12 |
| ATAD2 | CDCA3 | 0.818374 | 13 | 0 | 13 |
| ATAD2 | KIF20A | 0.818011 | 13 | 0 | 12 |
| ATAD2 | KIF2C | 0.814332 | 12 | 0 | 12 |
| ATAD2 | ECT2 | 0.812511 | 12 | 0 | 11 |
| ATAD2 | UBE2C | 0.812091 | 13 | 0 | 12 |
| ATAD2 | RAD51AP1 | 0.81146 | 13 | 0 | 13 |
For details and further investigation, click here
