| Full name: neurobeachin like 2 | Alias Symbol: KIAA0540 | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 23218 | HGNC ID: HGNC:31928 | Ensembl Gene: ENSG00000160796 | OMIM ID: 614169 |
| Drug and gene relationship at DGIdb | |||
Expression of NBEAL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NBEAL2 | 23218 | 212443_at | -0.6926 | 0.2982 | |
| GSE20347 | NBEAL2 | 23218 | 212443_at | -1.4456 | 0.0000 | |
| GSE23400 | NBEAL2 | 23218 | 212443_at | -1.2926 | 0.0000 | |
| GSE26886 | NBEAL2 | 23218 | 212443_at | -1.6406 | 0.0000 | |
| GSE29001 | NBEAL2 | 23218 | 212443_at | -1.2640 | 0.0006 | |
| GSE38129 | NBEAL2 | 23218 | 212443_at | -1.0266 | 0.0000 | |
| GSE45670 | NBEAL2 | 23218 | 212443_at | 0.0166 | 0.9435 | |
| GSE53622 | NBEAL2 | 23218 | 36570 | -1.6182 | 0.0000 | |
| GSE53624 | NBEAL2 | 23218 | 36570 | -1.7785 | 0.0000 | |
| GSE63941 | NBEAL2 | 23218 | 212443_at | 0.7880 | 0.0113 | |
| GSE77861 | NBEAL2 | 23218 | 212443_at | -0.6426 | 0.0105 | |
| GSE97050 | NBEAL2 | 23218 | A_24_P272160 | -0.0682 | 0.8915 | |
| SRP007169 | NBEAL2 | 23218 | RNAseq | -2.0593 | 0.0000 | |
| SRP008496 | NBEAL2 | 23218 | RNAseq | -2.3677 | 0.0000 | |
| SRP064894 | NBEAL2 | 23218 | RNAseq | -1.6385 | 0.0000 | |
| SRP133303 | NBEAL2 | 23218 | RNAseq | -1.8538 | 0.0000 | |
| SRP159526 | NBEAL2 | 23218 | RNAseq | -1.9229 | 0.0000 | |
| SRP193095 | NBEAL2 | 23218 | RNAseq | -0.8865 | 0.0000 | |
| SRP219564 | NBEAL2 | 23218 | RNAseq | -1.4066 | 0.0592 | |
| TCGA | NBEAL2 | 23218 | RNAseq | -0.1982 | 0.0158 |
Upregulated datasets: 0; Downregulated datasets: 12.
Survival by NBEAL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NBEAL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NBEAL2 | 23218 | 0 | 18 | 12 | |
| GSE20123 | NBEAL2 | 23218 | 0 | 19 | 11 | |
| GSE43470 | NBEAL2 | 23218 | 0 | 19 | 24 | |
| GSE46452 | NBEAL2 | 23218 | 2 | 17 | 40 | |
| GSE47630 | NBEAL2 | 23218 | 2 | 23 | 15 | |
| GSE54993 | NBEAL2 | 23218 | 7 | 2 | 61 | |
| GSE54994 | NBEAL2 | 23218 | 0 | 36 | 17 | |
| GSE60625 | NBEAL2 | 23218 | 5 | 0 | 6 | |
| GSE74703 | NBEAL2 | 23218 | 0 | 15 | 21 | |
| GSE74704 | NBEAL2 | 23218 | 0 | 12 | 8 | |
| TCGA | NBEAL2 | 23218 | 1 | 75 | 20 |
Total number of gains: 17; Total number of losses: 236; Total Number of normals: 235.
Somatic mutations of NBEAL2:
Generating mutation plots.
Highly correlated genes for NBEAL2:
Showing top 20/1415 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NBEAL2 | C6orf132 | 0.857672 | 7 | 0 | 7 |
| NBEAL2 | EVPL | 0.8421 | 13 | 0 | 12 |
| NBEAL2 | UPK3B | 0.821971 | 3 | 0 | 3 |
| NBEAL2 | DUOX1 | 0.820641 | 12 | 0 | 12 |
| NBEAL2 | TMEM154 | 0.81603 | 7 | 0 | 7 |
| NBEAL2 | S100A16 | 0.812505 | 7 | 0 | 7 |
| NBEAL2 | TMEM40 | 0.806323 | 12 | 0 | 12 |
| NBEAL2 | ARHGAP32 | 0.803679 | 11 | 0 | 11 |
| NBEAL2 | CLIC3 | 0.80086 | 10 | 0 | 10 |
| NBEAL2 | EPS8L1 | 0.799855 | 13 | 0 | 13 |
| NBEAL2 | RABGGTA | 0.797768 | 10 | 0 | 10 |
| NBEAL2 | TGM1 | 0.795884 | 12 | 0 | 12 |
| NBEAL2 | EPS8L2 | 0.795352 | 12 | 0 | 11 |
| NBEAL2 | LRP10 | 0.792871 | 10 | 0 | 10 |
| NBEAL2 | VSIG10L | 0.787655 | 7 | 0 | 7 |
| NBEAL2 | ARAP2 | 0.784933 | 3 | 0 | 3 |
| NBEAL2 | CEACAM7 | 0.78178 | 11 | 0 | 11 |
| NBEAL2 | ARHGAP40 | 0.779763 | 3 | 0 | 3 |
| NBEAL2 | TMEM79 | 0.779753 | 9 | 0 | 9 |
| NBEAL2 | RBM47 | 0.779197 | 12 | 0 | 12 |
For details and further investigation, click here
