| Full name: cyclin I | Alias Symbol: CCNI1 | ||
| Type: protein-coding gene | Cytoband: 4q21.1 | ||
| Entrez ID: 10983 | HGNC ID: HGNC:1595 | Ensembl Gene: ENSG00000118816 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CCNI:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCNI | 10983 | 208656_s_at | -0.3790 | 0.2966 | |
| GSE20347 | CCNI | 10983 | 208656_s_at | -0.6142 | 0.0002 | |
| GSE23400 | CCNI | 10983 | 208656_s_at | -0.4818 | 0.0000 | |
| GSE26886 | CCNI | 10983 | 208655_at | -0.9598 | 0.0002 | |
| GSE29001 | CCNI | 10983 | 208655_at | -0.9792 | 0.0187 | |
| GSE38129 | CCNI | 10983 | 208656_s_at | -0.6864 | 0.0000 | |
| GSE45670 | CCNI | 10983 | 208656_s_at | -0.7725 | 0.0000 | |
| GSE53622 | CCNI | 10983 | 64054 | -0.7912 | 0.0000 | |
| GSE53624 | CCNI | 10983 | 64054 | -0.7565 | 0.0000 | |
| GSE63941 | CCNI | 10983 | 208656_s_at | 0.0058 | 0.9862 | |
| GSE77861 | CCNI | 10983 | 208656_s_at | -0.4969 | 0.0605 | |
| GSE97050 | CCNI | 10983 | A_23_P69521 | -0.6839 | 0.0631 | |
| SRP007169 | CCNI | 10983 | RNAseq | -1.9110 | 0.0000 | |
| SRP008496 | CCNI | 10983 | RNAseq | -1.9076 | 0.0000 | |
| SRP064894 | CCNI | 10983 | RNAseq | -0.9543 | 0.0000 | |
| SRP133303 | CCNI | 10983 | RNAseq | -0.5353 | 0.0010 | |
| SRP159526 | CCNI | 10983 | RNAseq | -0.6500 | 0.0534 | |
| SRP193095 | CCNI | 10983 | RNAseq | -0.9981 | 0.0000 | |
| SRP219564 | CCNI | 10983 | RNAseq | -0.9895 | 0.0054 | |
| TCGA | CCNI | 10983 | RNAseq | -0.2425 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by CCNI expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCNI:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCNI | 10983 | 2 | 9 | 19 | |
| GSE20123 | CCNI | 10983 | 2 | 9 | 19 | |
| GSE43470 | CCNI | 10983 | 0 | 13 | 30 | |
| GSE46452 | CCNI | 10983 | 1 | 36 | 22 | |
| GSE47630 | CCNI | 10983 | 1 | 19 | 20 | |
| GSE54993 | CCNI | 10983 | 7 | 0 | 63 | |
| GSE54994 | CCNI | 10983 | 0 | 9 | 44 | |
| GSE60625 | CCNI | 10983 | 0 | 0 | 11 | |
| GSE74703 | CCNI | 10983 | 0 | 11 | 25 | |
| GSE74704 | CCNI | 10983 | 2 | 5 | 13 | |
| TCGA | CCNI | 10983 | 16 | 31 | 49 |
Total number of gains: 31; Total number of losses: 142; Total Number of normals: 315.
Somatic mutations of CCNI:
Generating mutation plots.
Highly correlated genes for CCNI:
Showing top 20/1546 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCNI | PSMD8 | 0.770487 | 3 | 0 | 3 |
| CCNI | ANGPTL1 | 0.766426 | 5 | 0 | 5 |
| CCNI | CYP4V2 | 0.759638 | 3 | 0 | 3 |
| CCNI | LIFR | 0.752351 | 5 | 0 | 5 |
| CCNI | USO1 | 0.735947 | 12 | 0 | 11 |
| CCNI | MTMR10 | 0.723732 | 7 | 0 | 7 |
| CCNI | MPP7 | 0.716386 | 6 | 0 | 6 |
| CCNI | MACROD2 | 0.711994 | 4 | 0 | 3 |
| CCNI | MAMDC2 | 0.711515 | 6 | 0 | 5 |
| CCNI | SPAG8 | 0.708653 | 4 | 0 | 4 |
| CCNI | LRRK2 | 0.707538 | 7 | 0 | 7 |
| CCNI | FBXL3 | 0.704983 | 4 | 0 | 4 |
| CCNI | LMBRD1 | 0.704677 | 12 | 0 | 11 |
| CCNI | SH3BGRL2 | 0.704137 | 7 | 0 | 6 |
| CCNI | ZNF608 | 0.70339 | 4 | 0 | 4 |
| CCNI | CTTNBP2 | 0.703302 | 6 | 0 | 6 |
| CCNI | HPGD | 0.702953 | 11 | 0 | 11 |
| CCNI | CGNL1 | 0.70181 | 8 | 0 | 7 |
| CCNI | GUF1 | 0.701761 | 4 | 0 | 4 |
| CCNI | ANO5 | 0.701605 | 5 | 0 | 5 |
For details and further investigation, click here
