| Full name: ADP ribosylation factor like GTPase 5A | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2q23.3 | ||
| Entrez ID: 26225 | HGNC ID: HGNC:696 | Ensembl Gene: ENSG00000162980 | OMIM ID: 608960 |
| Drug and gene relationship at DGIdb | |||
Expression of ARL5A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | ARL5A | 26225 | 16848 | -0.4733 | 0.0000 | |
| GSE53624 | ARL5A | 26225 | 16848 | -0.5194 | 0.0000 | |
| GSE97050 | ARL5A | 26225 | A_24_P165595 | -0.3027 | 0.4441 | |
| SRP007169 | ARL5A | 26225 | RNAseq | -0.8606 | 0.0223 | |
| SRP008496 | ARL5A | 26225 | RNAseq | -0.6969 | 0.0038 | |
| SRP064894 | ARL5A | 26225 | RNAseq | -0.4351 | 0.0173 | |
| SRP133303 | ARL5A | 26225 | RNAseq | 0.0817 | 0.6066 | |
| SRP159526 | ARL5A | 26225 | RNAseq | -0.2213 | 0.5582 | |
| SRP193095 | ARL5A | 26225 | RNAseq | -0.5263 | 0.0008 | |
| SRP219564 | ARL5A | 26225 | RNAseq | -0.5846 | 0.0254 | |
| TCGA | ARL5A | 26225 | RNAseq | -0.0408 | 0.3888 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ARL5A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARL5A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARL5A | 26225 | 3 | 2 | 25 | |
| GSE20123 | ARL5A | 26225 | 3 | 2 | 25 | |
| GSE43470 | ARL5A | 26225 | 3 | 1 | 39 | |
| GSE46452 | ARL5A | 26225 | 1 | 4 | 54 | |
| GSE47630 | ARL5A | 26225 | 5 | 3 | 32 | |
| GSE54993 | ARL5A | 26225 | 0 | 5 | 65 | |
| GSE54994 | ARL5A | 26225 | 11 | 2 | 40 | |
| GSE60625 | ARL5A | 26225 | 0 | 3 | 8 | |
| GSE74703 | ARL5A | 26225 | 2 | 1 | 33 | |
| GSE74704 | ARL5A | 26225 | 2 | 0 | 18 | |
| TCGA | ARL5A | 26225 | 22 | 8 | 66 |
Total number of gains: 52; Total number of losses: 31; Total Number of normals: 405.
Somatic mutations of ARL5A:
Generating mutation plots.
Highly correlated genes for ARL5A:
Showing top 20/73 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARL5A | UBR3 | 0.732662 | 3 | 0 | 3 |
| ARL5A | FYCO1 | 0.726601 | 3 | 0 | 3 |
| ARL5A | HIPK3 | 0.724509 | 3 | 0 | 3 |
| ARL5A | TDRD3 | 0.724431 | 3 | 0 | 3 |
| ARL5A | GAB1 | 0.723046 | 3 | 0 | 3 |
| ARL5A | RNF103 | 0.716048 | 3 | 0 | 3 |
| ARL5A | SENP6 | 0.715389 | 3 | 0 | 3 |
| ARL5A | PPP2CA | 0.713937 | 3 | 0 | 3 |
| ARL5A | SLC25A46 | 0.711946 | 3 | 0 | 3 |
| ARL5A | DMXL1 | 0.707961 | 3 | 0 | 3 |
| ARL5A | DYNC1I2 | 0.70638 | 3 | 0 | 3 |
| ARL5A | TOP2B | 0.705001 | 3 | 0 | 3 |
| ARL5A | CLIP1 | 0.70216 | 3 | 0 | 3 |
| ARL5A | CPEB4 | 0.696346 | 3 | 0 | 3 |
| ARL5A | STAM2 | 0.696036 | 3 | 0 | 3 |
| ARL5A | CPEB2 | 0.693519 | 3 | 0 | 3 |
| ARL5A | RAB11A | 0.692181 | 3 | 0 | 3 |
| ARL5A | LYSMD3 | 0.690084 | 3 | 0 | 3 |
| ARL5A | RC3H1 | 0.689211 | 3 | 0 | 3 |
| ARL5A | PIK3C2A | 0.688816 | 3 | 0 | 3 |
For details and further investigation, click here
