| Full name: tRNA nucleotidyl transferase 1 | Alias Symbol: MtCCA|CGI-47|CCA1 | ||
| Type: protein-coding gene | Cytoband: 3p26.2 | ||
| Entrez ID: 51095 | HGNC ID: HGNC:17341 | Ensembl Gene: ENSG00000072756 | OMIM ID: 612907 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TRNT1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRNT1 | 51095 | 222754_at | -0.1789 | 0.6978 | |
| GSE26886 | TRNT1 | 51095 | 222754_at | -0.3680 | 0.0942 | |
| GSE45670 | TRNT1 | 51095 | 222754_at | 0.3423 | 0.0180 | |
| GSE53622 | TRNT1 | 51095 | 60121 | -0.0305 | 0.6617 | |
| GSE53624 | TRNT1 | 51095 | 60121 | 0.0742 | 0.2124 | |
| GSE63941 | TRNT1 | 51095 | 222754_at | -0.3891 | 0.4141 | |
| GSE77861 | TRNT1 | 51095 | 222754_at | -0.1144 | 0.8252 | |
| GSE97050 | TRNT1 | 51095 | A_23_P372331 | 0.2284 | 0.3044 | |
| SRP007169 | TRNT1 | 51095 | RNAseq | 0.2998 | 0.4058 | |
| SRP008496 | TRNT1 | 51095 | RNAseq | 0.0739 | 0.7917 | |
| SRP064894 | TRNT1 | 51095 | RNAseq | -0.1865 | 0.1791 | |
| SRP133303 | TRNT1 | 51095 | RNAseq | -0.2468 | 0.0666 | |
| SRP159526 | TRNT1 | 51095 | RNAseq | -0.4750 | 0.1214 | |
| SRP193095 | TRNT1 | 51095 | RNAseq | -0.2919 | 0.0101 | |
| SRP219564 | TRNT1 | 51095 | RNAseq | -0.2500 | 0.3813 | |
| TCGA | TRNT1 | 51095 | RNAseq | -0.1568 | 0.0176 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TRNT1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRNT1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRNT1 | 51095 | 1 | 18 | 11 | |
| GSE20123 | TRNT1 | 51095 | 1 | 18 | 11 | |
| GSE43470 | TRNT1 | 51095 | 0 | 21 | 22 | |
| GSE46452 | TRNT1 | 51095 | 2 | 18 | 39 | |
| GSE47630 | TRNT1 | 51095 | 2 | 23 | 15 | |
| GSE54993 | TRNT1 | 51095 | 6 | 1 | 63 | |
| GSE54994 | TRNT1 | 51095 | 1 | 32 | 20 | |
| GSE60625 | TRNT1 | 51095 | 5 | 0 | 6 | |
| GSE74703 | TRNT1 | 51095 | 0 | 18 | 18 | |
| GSE74704 | TRNT1 | 51095 | 1 | 11 | 8 | |
| TCGA | TRNT1 | 51095 | 3 | 67 | 26 |
Total number of gains: 22; Total number of losses: 227; Total Number of normals: 239.
Somatic mutations of TRNT1:
Generating mutation plots.
Highly correlated genes for TRNT1:
Showing top 20/71 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRNT1 | CCDC112 | 0.755692 | 3 | 0 | 3 |
| TRNT1 | PNO1 | 0.737946 | 3 | 0 | 3 |
| TRNT1 | EXOC5 | 0.730252 | 3 | 0 | 3 |
| TRNT1 | DYNC1I2 | 0.727852 | 3 | 0 | 3 |
| TRNT1 | ANKRD9 | 0.722561 | 3 | 0 | 3 |
| TRNT1 | MRPL39 | 0.721443 | 3 | 0 | 3 |
| TRNT1 | THBD | 0.7041 | 3 | 0 | 3 |
| TRNT1 | KIN | 0.702296 | 3 | 0 | 3 |
| TRNT1 | MED4 | 0.697214 | 3 | 0 | 3 |
| TRNT1 | TMEM161B | 0.697209 | 3 | 0 | 3 |
| TRNT1 | RUFY3 | 0.685962 | 3 | 0 | 3 |
| TRNT1 | RNF6 | 0.684379 | 3 | 0 | 3 |
| TRNT1 | EZH2 | 0.681304 | 3 | 0 | 3 |
| TRNT1 | MPHOSPH10 | 0.675774 | 3 | 0 | 3 |
| TRNT1 | STON2 | 0.673223 | 3 | 0 | 3 |
| TRNT1 | CTCF | 0.672602 | 3 | 0 | 3 |
| TRNT1 | ZNF165 | 0.671008 | 3 | 0 | 3 |
| TRNT1 | UCHL3 | 0.669172 | 3 | 0 | 3 |
| TRNT1 | BDP1 | 0.66555 | 3 | 0 | 3 |
| TRNT1 | ANKRD12 | 0.664257 | 3 | 0 | 3 |
For details and further investigation, click here
