| Full name: dynein light chain roadblock-type 1 | Alias Symbol: DNLC2A|ROBLD1 | ||
| Type: protein-coding gene | Cytoband: 20q11.22 | ||
| Entrez ID: 83658 | HGNC ID: HGNC:15468 | Ensembl Gene: ENSG00000125971 | OMIM ID: 607167 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of DYNLRB1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DYNLRB1 | 83658 | 217918_at | 0.1351 | 0.7559 | |
| GSE20347 | DYNLRB1 | 83658 | 217917_s_at | -0.0862 | 0.5264 | |
| GSE23400 | DYNLRB1 | 83658 | 217918_at | -0.0094 | 0.9167 | |
| GSE26886 | DYNLRB1 | 83658 | 217917_s_at | -0.1027 | 0.6068 | |
| GSE29001 | DYNLRB1 | 83658 | 217917_s_at | 0.0006 | 0.9986 | |
| GSE38129 | DYNLRB1 | 83658 | 217917_s_at | -0.0908 | 0.4747 | |
| GSE45670 | DYNLRB1 | 83658 | 217917_s_at | -0.1187 | 0.4086 | |
| GSE53622 | DYNLRB1 | 83658 | 106166 | 0.1983 | 0.0005 | |
| GSE53624 | DYNLRB1 | 83658 | 106166 | 0.2426 | 0.0000 | |
| GSE63941 | DYNLRB1 | 83658 | 217918_at | 0.0933 | 0.8422 | |
| GSE77861 | DYNLRB1 | 83658 | 217917_s_at | 0.3010 | 0.3666 | |
| GSE97050 | DYNLRB1 | 83658 | A_24_P143440 | 0.2754 | 0.4463 | |
| SRP007169 | DYNLRB1 | 83658 | RNAseq | -0.9107 | 0.0089 | |
| SRP008496 | DYNLRB1 | 83658 | RNAseq | -0.4245 | 0.0806 | |
| SRP064894 | DYNLRB1 | 83658 | RNAseq | 0.4666 | 0.1651 | |
| SRP133303 | DYNLRB1 | 83658 | RNAseq | 0.1464 | 0.0672 | |
| SRP159526 | DYNLRB1 | 83658 | RNAseq | -0.3080 | 0.2572 | |
| SRP193095 | DYNLRB1 | 83658 | RNAseq | -0.0915 | 0.4937 | |
| SRP219564 | DYNLRB1 | 83658 | RNAseq | -0.0773 | 0.8192 | |
| TCGA | DYNLRB1 | 83658 | RNAseq | 0.0673 | 0.1840 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DYNLRB1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DYNLRB1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DYNLRB1 | 83658 | 16 | 0 | 14 | |
| GSE20123 | DYNLRB1 | 83658 | 16 | 0 | 14 | |
| GSE43470 | DYNLRB1 | 83658 | 12 | 0 | 31 | |
| GSE46452 | DYNLRB1 | 83658 | 29 | 0 | 30 | |
| GSE47630 | DYNLRB1 | 83658 | 24 | 1 | 15 | |
| GSE54993 | DYNLRB1 | 83658 | 0 | 18 | 52 | |
| GSE54994 | DYNLRB1 | 83658 | 25 | 1 | 27 | |
| GSE60625 | DYNLRB1 | 83658 | 0 | 0 | 11 | |
| GSE74703 | DYNLRB1 | 83658 | 11 | 0 | 25 | |
| GSE74704 | DYNLRB1 | 83658 | 11 | 0 | 9 | |
| TCGA | DYNLRB1 | 83658 | 50 | 2 | 44 |
Total number of gains: 194; Total number of losses: 22; Total Number of normals: 272.
Somatic mutations of DYNLRB1:
Generating mutation plots.
Highly correlated genes for DYNLRB1:
Showing top 20/238 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DYNLRB1 | NOL9 | 0.78117 | 3 | 0 | 3 |
| DYNLRB1 | KIAA1324L | 0.776174 | 3 | 0 | 3 |
| DYNLRB1 | STK11IP | 0.770578 | 3 | 0 | 3 |
| DYNLRB1 | POMGNT1 | 0.762077 | 3 | 0 | 3 |
| DYNLRB1 | ZBTB25 | 0.758079 | 3 | 0 | 3 |
| DYNLRB1 | SWT1 | 0.747154 | 3 | 0 | 3 |
| DYNLRB1 | VPS37C | 0.741973 | 3 | 0 | 3 |
| DYNLRB1 | MKNK1 | 0.737055 | 3 | 0 | 3 |
| DYNLRB1 | MECP2 | 0.712074 | 3 | 0 | 3 |
| DYNLRB1 | NUCB1 | 0.709497 | 3 | 0 | 3 |
| DYNLRB1 | ZNF213 | 0.70728 | 3 | 0 | 3 |
| DYNLRB1 | HGS | 0.706936 | 4 | 0 | 3 |
| DYNLRB1 | MOB3C | 0.704965 | 3 | 0 | 3 |
| DYNLRB1 | GABRA3 | 0.702691 | 3 | 0 | 3 |
| DYNLRB1 | ROMO1 | 0.697737 | 4 | 0 | 4 |
| DYNLRB1 | ANKZF1 | 0.694976 | 3 | 0 | 3 |
| DYNLRB1 | RNF220 | 0.685495 | 4 | 0 | 3 |
| DYNLRB1 | CHST11 | 0.678211 | 3 | 0 | 3 |
| DYNLRB1 | FAM53B | 0.673674 | 3 | 0 | 3 |
| DYNLRB1 | TAPBP | 0.673413 | 3 | 0 | 3 |
For details and further investigation, click here
