| Full name: ELL associated factor 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3p25.1 | ||
| Entrez ID: 85403 | HGNC ID: HGNC:20907 | Ensembl Gene: ENSG00000144597 | OMIM ID: 608315 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of EAF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EAF1 | 85403 | 226952_at | 0.1285 | 0.7886 | |
| GSE26886 | EAF1 | 85403 | 226952_at | -1.3304 | 0.0000 | |
| GSE45670 | EAF1 | 85403 | 226952_at | 0.1180 | 0.4853 | |
| GSE53622 | EAF1 | 85403 | 44011 | -0.1930 | 0.0073 | |
| GSE53624 | EAF1 | 85403 | 44011 | -0.1997 | 0.0383 | |
| GSE63941 | EAF1 | 85403 | 226952_at | -0.4385 | 0.4522 | |
| GSE77861 | EAF1 | 85403 | 226952_at | -0.1231 | 0.4338 | |
| GSE97050 | EAF1 | 85403 | A_24_P941930 | 0.1727 | 0.4822 | |
| SRP007169 | EAF1 | 85403 | RNAseq | -0.8328 | 0.0101 | |
| SRP008496 | EAF1 | 85403 | RNAseq | -0.4324 | 0.0802 | |
| SRP064894 | EAF1 | 85403 | RNAseq | -0.1882 | 0.4062 | |
| SRP133303 | EAF1 | 85403 | RNAseq | -0.1557 | 0.1137 | |
| SRP159526 | EAF1 | 85403 | RNAseq | -0.3556 | 0.2307 | |
| SRP193095 | EAF1 | 85403 | RNAseq | -0.3631 | 0.0003 | |
| SRP219564 | EAF1 | 85403 | RNAseq | -0.3478 | 0.1980 | |
| TCGA | EAF1 | 85403 | RNAseq | -0.1874 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by EAF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EAF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EAF1 | 85403 | 2 | 19 | 9 | |
| GSE20123 | EAF1 | 85403 | 2 | 19 | 9 | |
| GSE43470 | EAF1 | 85403 | 0 | 21 | 22 | |
| GSE46452 | EAF1 | 85403 | 2 | 17 | 40 | |
| GSE47630 | EAF1 | 85403 | 2 | 23 | 15 | |
| GSE54993 | EAF1 | 85403 | 6 | 1 | 63 | |
| GSE54994 | EAF1 | 85403 | 1 | 32 | 20 | |
| GSE60625 | EAF1 | 85403 | 5 | 0 | 6 | |
| GSE74703 | EAF1 | 85403 | 0 | 17 | 19 | |
| GSE74704 | EAF1 | 85403 | 1 | 13 | 6 | |
| TCGA | EAF1 | 85403 | 2 | 68 | 26 |
Total number of gains: 23; Total number of losses: 230; Total Number of normals: 235.
Somatic mutations of EAF1:
Generating mutation plots.
Highly correlated genes for EAF1:
Showing top 20/508 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EAF1 | SPTLC3 | 0.818238 | 3 | 0 | 3 |
| EAF1 | RNGTT | 0.794461 | 3 | 0 | 3 |
| EAF1 | POLE3 | 0.789014 | 3 | 0 | 3 |
| EAF1 | DNAJC7 | 0.782693 | 3 | 0 | 3 |
| EAF1 | PJA2 | 0.780959 | 3 | 0 | 3 |
| EAF1 | TPD52L2 | 0.77758 | 3 | 0 | 3 |
| EAF1 | PPP1R3D | 0.769823 | 3 | 0 | 3 |
| EAF1 | SNAP29 | 0.758598 | 3 | 0 | 3 |
| EAF1 | GPD2 | 0.758532 | 3 | 0 | 3 |
| EAF1 | KCMF1 | 0.756198 | 3 | 0 | 3 |
| EAF1 | HIPK1 | 0.754927 | 3 | 0 | 3 |
| EAF1 | LTN1 | 0.745201 | 4 | 0 | 4 |
| EAF1 | ADCY7 | 0.734692 | 4 | 0 | 4 |
| EAF1 | RNFT1 | 0.732744 | 3 | 0 | 3 |
| EAF1 | YES1 | 0.730157 | 3 | 0 | 3 |
| EAF1 | MED7 | 0.72952 | 3 | 0 | 3 |
| EAF1 | SLC2A9 | 0.72811 | 3 | 0 | 3 |
| EAF1 | ZNF92 | 0.728084 | 3 | 0 | 3 |
| EAF1 | UNC5B | 0.724145 | 3 | 0 | 3 |
| EAF1 | PPHLN1 | 0.72098 | 3 | 0 | 3 |
For details and further investigation, click here
