| Full name: zinc finger protein 543 | Alias Symbol: DKFZp434H055 | ||
| Type: protein-coding gene | Cytoband: 19q13.43 | ||
| Entrez ID: 125919 | HGNC ID: HGNC:25281 | Ensembl Gene: ENSG00000178229 | OMIM ID: 616847 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF543:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF543 | 125919 | 240191_at | -0.0432 | 0.8934 | |
| GSE26886 | ZNF543 | 125919 | 240191_at | 0.1098 | 0.4688 | |
| GSE45670 | ZNF543 | 125919 | 240191_at | -0.1424 | 0.0720 | |
| GSE53622 | ZNF543 | 125919 | 6238 | -0.2346 | 0.0059 | |
| GSE53624 | ZNF543 | 125919 | 6238 | -0.1691 | 0.0991 | |
| GSE63941 | ZNF543 | 125919 | 240191_at | 0.3099 | 0.0919 | |
| GSE77861 | ZNF543 | 125919 | 240191_at | -0.0554 | 0.5527 | |
| GSE97050 | ZNF543 | 125919 | A_32_P139229 | 0.1221 | 0.7032 | |
| SRP007169 | ZNF543 | 125919 | RNAseq | -0.3896 | 0.2802 | |
| SRP008496 | ZNF543 | 125919 | RNAseq | -0.2773 | 0.3942 | |
| SRP064894 | ZNF543 | 125919 | RNAseq | -0.6770 | 0.0016 | |
| SRP133303 | ZNF543 | 125919 | RNAseq | 0.0072 | 0.9670 | |
| SRP159526 | ZNF543 | 125919 | RNAseq | 0.2192 | 0.4787 | |
| SRP193095 | ZNF543 | 125919 | RNAseq | -0.1565 | 0.1905 | |
| SRP219564 | ZNF543 | 125919 | RNAseq | -0.2299 | 0.4944 | |
| TCGA | ZNF543 | 125919 | RNAseq | -0.0201 | 0.8101 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZNF543 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF543:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF543 | 125919 | 2 | 4 | 24 | |
| GSE20123 | ZNF543 | 125919 | 2 | 3 | 25 | |
| GSE43470 | ZNF543 | 125919 | 2 | 9 | 32 | |
| GSE46452 | ZNF543 | 125919 | 45 | 1 | 13 | |
| GSE47630 | ZNF543 | 125919 | 8 | 6 | 26 | |
| GSE54993 | ZNF543 | 125919 | 18 | 4 | 48 | |
| GSE54994 | ZNF543 | 125919 | 5 | 12 | 36 | |
| GSE60625 | ZNF543 | 125919 | 9 | 0 | 2 | |
| GSE74703 | ZNF543 | 125919 | 2 | 6 | 28 | |
| GSE74704 | ZNF543 | 125919 | 2 | 1 | 17 | |
| TCGA | ZNF543 | 125919 | 21 | 16 | 59 |
Total number of gains: 116; Total number of losses: 62; Total Number of normals: 310.
Somatic mutations of ZNF543:
Generating mutation plots.
Highly correlated genes for ZNF543:
Showing top 20/141 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF543 | ECHDC1 | 0.760759 | 3 | 0 | 3 |
| ZNF543 | PSEN1 | 0.747401 | 3 | 0 | 3 |
| ZNF543 | E2F8 | 0.743299 | 3 | 0 | 3 |
| ZNF543 | EXOC2 | 0.733636 | 3 | 0 | 3 |
| ZNF543 | PIK3R5 | 0.730772 | 3 | 0 | 3 |
| ZNF543 | VPS26A | 0.728217 | 3 | 0 | 3 |
| ZNF543 | BNIP1 | 0.727575 | 3 | 0 | 3 |
| ZNF543 | IMP3 | 0.725227 | 3 | 0 | 3 |
| ZNF543 | DNPEP | 0.7226 | 3 | 0 | 3 |
| ZNF543 | SLC25A40 | 0.712654 | 3 | 0 | 3 |
| ZNF543 | ASL | 0.710009 | 3 | 0 | 3 |
| ZNF543 | SDHB | 0.709457 | 4 | 0 | 4 |
| ZNF543 | ZNF304 | 0.704417 | 5 | 0 | 4 |
| ZNF543 | MRPS18B | 0.702536 | 4 | 0 | 3 |
| ZNF543 | CNOT10 | 0.699264 | 3 | 0 | 3 |
| ZNF543 | ZNF394 | 0.697263 | 3 | 0 | 3 |
| ZNF543 | MTO1 | 0.696757 | 3 | 0 | 3 |
| ZNF543 | LIPT1 | 0.696211 | 3 | 0 | 3 |
| ZNF543 | ZNF12 | 0.693727 | 3 | 0 | 3 |
| ZNF543 | ZW10 | 0.693604 | 4 | 0 | 3 |
For details and further investigation, click here
