| Full name: EF-hand calcium binding domain 2 | Alias Symbol: MGC12458|DRC8|CFAP200 | ||
| Type: protein-coding gene | Cytoband: 1q44 | ||
| Entrez ID: 84288 | HGNC ID: HGNC:28166 | Ensembl Gene: ENSG00000203666 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of EFCAB2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EFCAB2 | 84288 | 211200_s_at | 0.1302 | 0.8691 | |
| GSE20347 | EFCAB2 | 84288 | 211200_s_at | 0.2432 | 0.0604 | |
| GSE23400 | EFCAB2 | 84288 | 207572_at | -0.1163 | 0.0000 | |
| GSE26886 | EFCAB2 | 84288 | 211200_s_at | 1.3287 | 0.0009 | |
| GSE29001 | EFCAB2 | 84288 | 211200_s_at | 0.4660 | 0.1736 | |
| GSE38129 | EFCAB2 | 84288 | 211200_s_at | 0.2080 | 0.3010 | |
| GSE45670 | EFCAB2 | 84288 | 211200_s_at | -0.0483 | 0.8416 | |
| GSE53622 | EFCAB2 | 84288 | 89927 | -0.0357 | 0.8514 | |
| GSE53624 | EFCAB2 | 84288 | 89927 | 0.4440 | 0.0040 | |
| GSE63941 | EFCAB2 | 84288 | 223608_at | -0.4504 | 0.4459 | |
| GSE77861 | EFCAB2 | 84288 | 207572_at | -0.0517 | 0.5693 | |
| GSE97050 | EFCAB2 | 84288 | A_23_P149476 | -0.4074 | 0.2363 | |
| SRP007169 | EFCAB2 | 84288 | RNAseq | -0.2332 | 0.7265 | |
| SRP064894 | EFCAB2 | 84288 | RNAseq | 0.2673 | 0.2591 | |
| SRP133303 | EFCAB2 | 84288 | RNAseq | 0.0589 | 0.7246 | |
| SRP159526 | EFCAB2 | 84288 | RNAseq | 0.3066 | 0.3328 | |
| SRP193095 | EFCAB2 | 84288 | RNAseq | 0.2991 | 0.0183 | |
| SRP219564 | EFCAB2 | 84288 | RNAseq | 0.3393 | 0.4558 | |
| TCGA | EFCAB2 | 84288 | RNAseq | -0.3772 | 0.0161 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by EFCAB2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EFCAB2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EFCAB2 | 84288 | 7 | 1 | 22 | |
| GSE20123 | EFCAB2 | 84288 | 7 | 1 | 22 | |
| GSE43470 | EFCAB2 | 84288 | 6 | 2 | 35 | |
| GSE46452 | EFCAB2 | 84288 | 4 | 2 | 53 | |
| GSE47630 | EFCAB2 | 84288 | 14 | 2 | 24 | |
| GSE54993 | EFCAB2 | 84288 | 0 | 6 | 64 | |
| GSE54994 | EFCAB2 | 84288 | 18 | 0 | 35 | |
| GSE60625 | EFCAB2 | 84288 | 0 | 0 | 11 | |
| GSE74703 | EFCAB2 | 84288 | 6 | 1 | 29 | |
| GSE74704 | EFCAB2 | 84288 | 2 | 0 | 18 | |
| TCGA | EFCAB2 | 84288 | 46 | 4 | 46 |
Total number of gains: 110; Total number of losses: 19; Total Number of normals: 359.
Somatic mutations of EFCAB2:
Generating mutation plots.
Highly correlated genes for EFCAB2:
Showing top 20/169 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EFCAB2 | ZNF584 | 0.723992 | 4 | 0 | 4 |
| EFCAB2 | RIMKLB | 0.710886 | 3 | 0 | 3 |
| EFCAB2 | TCEA2 | 0.703869 | 4 | 0 | 4 |
| EFCAB2 | XKR6 | 0.691022 | 3 | 0 | 3 |
| EFCAB2 | NTPCR | 0.690396 | 3 | 0 | 3 |
| EFCAB2 | C9orf64 | 0.688709 | 3 | 0 | 3 |
| EFCAB2 | RP9 | 0.683676 | 4 | 0 | 3 |
| EFCAB2 | TNRC18 | 0.676586 | 3 | 0 | 3 |
| EFCAB2 | ALKBH6 | 0.676022 | 3 | 0 | 3 |
| EFCAB2 | USP11 | 0.675826 | 4 | 0 | 4 |
| EFCAB2 | STAT5A | 0.663005 | 3 | 0 | 3 |
| EFCAB2 | PCOLCE2 | 0.661067 | 4 | 0 | 3 |
| EFCAB2 | AKAP8L | 0.659529 | 4 | 0 | 4 |
| EFCAB2 | PTOV1 | 0.656486 | 3 | 0 | 3 |
| EFCAB2 | INPP5E | 0.651514 | 4 | 0 | 3 |
| EFCAB2 | DCAF16 | 0.6504 | 4 | 0 | 3 |
| EFCAB2 | ETV6 | 0.647362 | 3 | 0 | 3 |
| EFCAB2 | NDUFAF4 | 0.643942 | 4 | 0 | 3 |
| EFCAB2 | DDX42 | 0.637793 | 3 | 0 | 3 |
| EFCAB2 | DYNC2LI1 | 0.637462 | 4 | 0 | 4 |
For details and further investigation, click here
