| Full name: NADH:ubiquinone oxidoreductase complex assembly factor 4 | Alias Symbol: HSPC125|bA22L21.1|My013|HRPAP20 | ||
| Type: protein-coding gene | Cytoband: 6q16.1 | ||
| Entrez ID: 29078 | HGNC ID: HGNC:21034 | Ensembl Gene: ENSG00000123545 | OMIM ID: 611776 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NDUFAF4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NDUFAF4 | 29078 | 219006_at | 0.0790 | 0.8889 | |
| GSE20347 | NDUFAF4 | 29078 | 219006_at | 0.5447 | 0.0179 | |
| GSE23400 | NDUFAF4 | 29078 | 219006_at | 0.1979 | 0.0000 | |
| GSE26886 | NDUFAF4 | 29078 | 219006_at | 0.7103 | 0.0085 | |
| GSE29001 | NDUFAF4 | 29078 | 219006_at | 0.4583 | 0.1429 | |
| GSE38129 | NDUFAF4 | 29078 | 219006_at | 0.5444 | 0.0016 | |
| GSE45670 | NDUFAF4 | 29078 | 219006_at | 0.4434 | 0.0096 | |
| GSE53622 | NDUFAF4 | 29078 | 105 | 0.0323 | 0.7525 | |
| GSE53624 | NDUFAF4 | 29078 | 105 | 0.4801 | 0.0000 | |
| GSE63941 | NDUFAF4 | 29078 | 219006_at | 0.0845 | 0.8986 | |
| GSE77861 | NDUFAF4 | 29078 | 219006_at | 0.5455 | 0.1970 | |
| GSE97050 | NDUFAF4 | 29078 | A_24_P171983 | -0.2507 | 0.4073 | |
| SRP007169 | NDUFAF4 | 29078 | RNAseq | 0.8306 | 0.1157 | |
| SRP008496 | NDUFAF4 | 29078 | RNAseq | 1.0645 | 0.0029 | |
| SRP064894 | NDUFAF4 | 29078 | RNAseq | -0.1891 | 0.3488 | |
| SRP133303 | NDUFAF4 | 29078 | RNAseq | 0.0796 | 0.6488 | |
| SRP159526 | NDUFAF4 | 29078 | RNAseq | 0.3798 | 0.2971 | |
| SRP193095 | NDUFAF4 | 29078 | RNAseq | -0.0733 | 0.6490 | |
| SRP219564 | NDUFAF4 | 29078 | RNAseq | -0.0397 | 0.9150 | |
| TCGA | NDUFAF4 | 29078 | RNAseq | -0.0226 | 0.7793 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by NDUFAF4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NDUFAF4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NDUFAF4 | 29078 | 1 | 3 | 26 | |
| GSE20123 | NDUFAF4 | 29078 | 1 | 2 | 27 | |
| GSE43470 | NDUFAF4 | 29078 | 3 | 2 | 38 | |
| GSE46452 | NDUFAF4 | 29078 | 2 | 11 | 46 | |
| GSE47630 | NDUFAF4 | 29078 | 8 | 6 | 26 | |
| GSE54993 | NDUFAF4 | 29078 | 3 | 2 | 65 | |
| GSE54994 | NDUFAF4 | 29078 | 8 | 8 | 37 | |
| GSE60625 | NDUFAF4 | 29078 | 0 | 1 | 10 | |
| GSE74703 | NDUFAF4 | 29078 | 2 | 2 | 32 | |
| GSE74704 | NDUFAF4 | 29078 | 0 | 0 | 20 | |
| TCGA | NDUFAF4 | 29078 | 4 | 25 | 67 |
Total number of gains: 32; Total number of losses: 62; Total Number of normals: 394.
Somatic mutations of NDUFAF4:
Generating mutation plots.
Highly correlated genes for NDUFAF4:
Showing top 20/815 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NDUFAF4 | RAMP1 | 0.738632 | 3 | 0 | 3 |
| NDUFAF4 | KLF11 | 0.730565 | 3 | 0 | 3 |
| NDUFAF4 | ZNF251 | 0.720728 | 3 | 0 | 3 |
| NDUFAF4 | DDIAS | 0.701646 | 3 | 0 | 3 |
| NDUFAF4 | MRPL51 | 0.701615 | 4 | 0 | 4 |
| NDUFAF4 | PDE9A | 0.693668 | 3 | 0 | 3 |
| NDUFAF4 | SLIT2 | 0.681618 | 3 | 0 | 3 |
| NDUFAF4 | PTPMT1 | 0.677937 | 3 | 0 | 3 |
| NDUFAF4 | C11orf58 | 0.67608 | 5 | 0 | 4 |
| NDUFAF4 | HSD17B11 | 0.673462 | 4 | 0 | 4 |
| NDUFAF4 | DNAJC19 | 0.672465 | 3 | 0 | 3 |
| NDUFAF4 | COX7B | 0.667089 | 4 | 0 | 3 |
| NDUFAF4 | GMPR | 0.664825 | 3 | 0 | 3 |
| NDUFAF4 | TMTC1 | 0.664283 | 3 | 0 | 3 |
| NDUFAF4 | SLC19A2 | 0.66366 | 3 | 0 | 3 |
| NDUFAF4 | CCDC138 | 0.663602 | 4 | 0 | 4 |
| NDUFAF4 | NUFIP2 | 0.661007 | 3 | 0 | 3 |
| NDUFAF4 | CCDC86 | 0.660799 | 8 | 0 | 8 |
| NDUFAF4 | IDH3A | 0.658302 | 6 | 0 | 6 |
| NDUFAF4 | ATAD5 | 0.65809 | 3 | 0 | 3 |
For details and further investigation, click here
