| Full name: ephrin B1 | Alias Symbol: LERK2|Elk-L | ||
| Type: protein-coding gene | Cytoband: Xq13.1 | ||
| Entrez ID: 1947 | HGNC ID: HGNC:3226 | Ensembl Gene: ENSG00000090776 | OMIM ID: 300035 |
| Drug and gene relationship at DGIdb | |||
EFNB1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04360 | Axon guidance |
Expression of EFNB1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EFNB1 | 1947 | 202711_at | 1.0414 | 0.0466 | |
| GSE20347 | EFNB1 | 1947 | 202711_at | 0.5576 | 0.0000 | |
| GSE23400 | EFNB1 | 1947 | 202711_at | 0.4685 | 0.0000 | |
| GSE26886 | EFNB1 | 1947 | 202711_at | 0.4707 | 0.0011 | |
| GSE29001 | EFNB1 | 1947 | 202711_at | 0.1220 | 0.4084 | |
| GSE38129 | EFNB1 | 1947 | 202711_at | 0.5672 | 0.0000 | |
| GSE45670 | EFNB1 | 1947 | 202711_at | 0.1964 | 0.1001 | |
| GSE53622 | EFNB1 | 1947 | 1552 | 1.1994 | 0.0000 | |
| GSE53624 | EFNB1 | 1947 | 129506 | 1.1685 | 0.0000 | |
| GSE63941 | EFNB1 | 1947 | 202711_at | 0.4054 | 0.2429 | |
| GSE77861 | EFNB1 | 1947 | 202711_at | 0.4056 | 0.0514 | |
| GSE97050 | EFNB1 | 1947 | A_24_P365807 | 0.5980 | 0.1939 | |
| SRP007169 | EFNB1 | 1947 | RNAseq | 1.5498 | 0.0023 | |
| SRP008496 | EFNB1 | 1947 | RNAseq | 1.9103 | 0.0000 | |
| SRP064894 | EFNB1 | 1947 | RNAseq | 1.6075 | 0.0000 | |
| SRP133303 | EFNB1 | 1947 | RNAseq | 1.6227 | 0.0000 | |
| SRP159526 | EFNB1 | 1947 | RNAseq | 0.7095 | 0.0862 | |
| SRP193095 | EFNB1 | 1947 | RNAseq | 1.5075 | 0.0000 | |
| SRP219564 | EFNB1 | 1947 | RNAseq | 1.0046 | 0.0613 | |
| TCGA | EFNB1 | 1947 | RNAseq | 0.5656 | 0.0000 |
Upregulated datasets: 8; Downregulated datasets: 0.
Survival by EFNB1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EFNB1:
No record found for this gene.
Somatic mutations of EFNB1:
Generating mutation plots.
Highly correlated genes for EFNB1:
Showing top 20/742 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EFNB1 | ADAP1 | 0.762403 | 3 | 0 | 3 |
| EFNB1 | C16orf74 | 0.761617 | 5 | 0 | 5 |
| EFNB1 | CD276 | 0.744681 | 4 | 0 | 4 |
| EFNB1 | POLE4 | 0.739727 | 5 | 0 | 5 |
| EFNB1 | ATAD3C | 0.725901 | 3 | 0 | 3 |
| EFNB1 | GPRIN1 | 0.722961 | 7 | 0 | 6 |
| EFNB1 | SLC34A1 | 0.720985 | 3 | 0 | 3 |
| EFNB1 | RASL11B | 0.705006 | 5 | 0 | 5 |
| EFNB1 | BOP1 | 0.704638 | 3 | 0 | 3 |
| EFNB1 | CCDC142 | 0.699666 | 3 | 0 | 3 |
| EFNB1 | AIFM3 | 0.696277 | 4 | 0 | 3 |
| EFNB1 | SCAMP5 | 0.689415 | 4 | 0 | 4 |
| EFNB1 | ADRA1B | 0.688784 | 3 | 0 | 3 |
| EFNB1 | ZFPM1 | 0.688014 | 4 | 0 | 3 |
| EFNB1 | USB1 | 0.679861 | 10 | 0 | 8 |
| EFNB1 | NTMT1 | 0.67387 | 5 | 0 | 4 |
| EFNB1 | CENPW | 0.673564 | 4 | 0 | 4 |
| EFNB1 | CKAP2L | 0.672785 | 3 | 0 | 3 |
| EFNB1 | CDCA5 | 0.671216 | 6 | 0 | 6 |
| EFNB1 | RFX8 | 0.668848 | 3 | 0 | 3 |
For details and further investigation, click here
