| Full name: eukaryotic translation initiation factor 3 subunit D | Alias Symbol: eIF3-p66|eIF3-zeta|eIF3d | ||
| Type: protein-coding gene | Cytoband: 22q12.3 | ||
| Entrez ID: 8664 | HGNC ID: HGNC:3278 | Ensembl Gene: ENSG00000100353 | OMIM ID: 603915 |
| Drug and gene relationship at DGIdb | |||
Expression of EIF3D:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EIF3D | 8664 | 200005_at | -0.0746 | 0.8494 | |
| GSE20347 | EIF3D | 8664 | 200005_at | -0.1616 | 0.3064 | |
| GSE23400 | EIF3D | 8664 | 200005_at | 0.0416 | 0.5457 | |
| GSE26886 | EIF3D | 8664 | 200005_at | 0.4015 | 0.0346 | |
| GSE29001 | EIF3D | 8664 | 200005_at | -0.2990 | 0.5397 | |
| GSE38129 | EIF3D | 8664 | 200005_at | 0.0215 | 0.8651 | |
| GSE45670 | EIF3D | 8664 | 200005_at | -0.1541 | 0.2443 | |
| GSE53622 | EIF3D | 8664 | 104548 | -0.1548 | 0.0039 | |
| GSE53624 | EIF3D | 8664 | 104548 | -0.0761 | 0.0541 | |
| GSE63941 | EIF3D | 8664 | 200005_at | 0.6968 | 0.0078 | |
| GSE77861 | EIF3D | 8664 | 200005_at | 0.2559 | 0.3140 | |
| GSE97050 | EIF3D | 8664 | A_23_P91702 | 0.1577 | 0.4532 | |
| SRP007169 | EIF3D | 8664 | RNAseq | -0.7053 | 0.0135 | |
| SRP008496 | EIF3D | 8664 | RNAseq | -0.7326 | 0.0003 | |
| SRP064894 | EIF3D | 8664 | RNAseq | 0.1259 | 0.5205 | |
| SRP133303 | EIF3D | 8664 | RNAseq | -0.3119 | 0.0502 | |
| SRP159526 | EIF3D | 8664 | RNAseq | -0.2379 | 0.2678 | |
| SRP193095 | EIF3D | 8664 | RNAseq | -0.3411 | 0.0011 | |
| SRP219564 | EIF3D | 8664 | RNAseq | -0.0927 | 0.7417 | |
| TCGA | EIF3D | 8664 | RNAseq | 0.0352 | 0.3946 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by EIF3D expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EIF3D:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EIF3D | 8664 | 6 | 6 | 18 | |
| GSE20123 | EIF3D | 8664 | 6 | 5 | 19 | |
| GSE43470 | EIF3D | 8664 | 4 | 6 | 33 | |
| GSE46452 | EIF3D | 8664 | 31 | 1 | 27 | |
| GSE47630 | EIF3D | 8664 | 8 | 5 | 27 | |
| GSE54993 | EIF3D | 8664 | 3 | 6 | 61 | |
| GSE54994 | EIF3D | 8664 | 9 | 9 | 35 | |
| GSE60625 | EIF3D | 8664 | 5 | 0 | 6 | |
| GSE74703 | EIF3D | 8664 | 4 | 4 | 28 | |
| GSE74704 | EIF3D | 8664 | 3 | 2 | 15 | |
| TCGA | EIF3D | 8664 | 27 | 15 | 54 |
Total number of gains: 106; Total number of losses: 59; Total Number of normals: 323.
Somatic mutations of EIF3D:
Generating mutation plots.
Highly correlated genes for EIF3D:
Showing top 20/390 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EIF3D | TRIM28 | 0.769514 | 3 | 0 | 3 |
| EIF3D | VPS25 | 0.74273 | 3 | 0 | 3 |
| EIF3D | GMCL1 | 0.736483 | 3 | 0 | 3 |
| EIF3D | OTUD7B | 0.729201 | 3 | 0 | 3 |
| EIF3D | MYO1D | 0.718535 | 3 | 0 | 3 |
| EIF3D | TUBA1B | 0.716794 | 3 | 0 | 3 |
| EIF3D | MRPL21 | 0.712944 | 3 | 0 | 3 |
| EIF3D | CLTA | 0.701354 | 3 | 0 | 3 |
| EIF3D | ANKRD54 | 0.701168 | 3 | 0 | 3 |
| EIF3D | CHCHD2 | 0.700483 | 5 | 0 | 5 |
| EIF3D | NSUN5 | 0.694756 | 3 | 0 | 3 |
| EIF3D | TSTD1 | 0.694262 | 3 | 0 | 3 |
| EIF3D | ORMDL3 | 0.694046 | 3 | 0 | 3 |
| EIF3D | WDR20 | 0.692298 | 3 | 0 | 3 |
| EIF3D | ATP11B | 0.690172 | 3 | 0 | 3 |
| EIF3D | ARIH1 | 0.689705 | 3 | 0 | 3 |
| EIF3D | COPZ1 | 0.685192 | 4 | 0 | 4 |
| EIF3D | ASCC1 | 0.682354 | 5 | 0 | 4 |
| EIF3D | POLB | 0.681907 | 3 | 0 | 3 |
| EIF3D | ERP29 | 0.677946 | 5 | 0 | 4 |
For details and further investigation, click here
