EML1

 

Full name: EMAP like 1 Alias Symbol: EMAP|HuEMAP|ELP79
Type: protein-coding gene Cytoband: 14q32.2
Entrez ID: 2009 HGNC ID: HGNC:3330 Ensembl Gene: ENSG00000066629 OMIM ID: 602033
Drug and gene relationship at DGIdb

 

Expression of EML1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 EML1 2009 204797_s_at -0.7120 0.5494
GSE20347 EML1 2009 204797_s_at 0.0039 0.9926
GSE23400 EML1 2009 204797_s_at -0.4197 0.0225
GSE26886 EML1 2009 204797_s_at 1.0274 0.0243
GSE29001 EML1 2009 204797_s_at -0.0618 0.8770
GSE38129 EML1 2009 204797_s_at -0.4795 0.2886
GSE45670 EML1 2009 204797_s_at -1.0541 0.0042
GSE53622 EML1 2009 30184 -0.2015 0.1784
GSE53624 EML1 2009 10210 -0.3887 0.0000
GSE63941 EML1 2009 204797_s_at -3.6614 0.0045
GSE77861 EML1 2009 204797_s_at 1.1502 0.0556
GSE97050 EML1 2009 A_33_P3219942 -1.0252 0.1729
SRP007169 EML1 2009 RNAseq 1.1408 0.1336
SRP008496 EML1 2009 RNAseq 1.2756 0.0082
SRP064894 EML1 2009 RNAseq -0.3262 0.2970
SRP133303 EML1 2009 RNAseq 0.3572 0.3139
SRP159526 EML1 2009 RNAseq 0.1578 0.7231
SRP193095 EML1 2009 RNAseq 0.4765 0.0107
SRP219564 EML1 2009 RNAseq -0.0381 0.9625
TCGA EML1 2009 RNAseq -0.3708 0.0027

Upregulated datasets: 2; Downregulated datasets: 2.  


 

Survival by EML1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of EML1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 EML1 2009 10 5 15
GSE20123 EML1 2009 10 4 16
GSE43470 EML1 2009 7 4 32
GSE46452 EML1 2009 17 3 39
GSE47630 EML1 2009 11 8 21
GSE54993 EML1 2009 3 8 59
GSE54994 EML1 2009 21 4 28
GSE60625 EML1 2009 0 2 9
GSE74703 EML1 2009 6 3 27
GSE74704 EML1 2009 6 3 11
TCGA EML1 2009 31 18 47

Total number of gains: 122; Total number of losses: 62; Total Number of normals: 304.  


 

Somatic mutations of EML1:

 

Generating mutation plots.

 

Highly correlated genes for EML1:

 

Showing top 20/1003 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
EML1SYNC0.771533707
EML1NCOR20.751738303
EML1JPH20.750035404
EML1FAM98B0.743174303
EML1MAP40.742693505
EML1ADAM230.742612404
EML1FERMT20.73637711011
EML1MGARP0.728253303
EML1BDNF0.722015303
EML1MRGPRF0.720447706
EML1FLNA0.717508807
EML1STARD90.716149505
EML1RAB33B0.713434303
EML1COX7A10.71176910010
EML1SGCA0.711446706
EML1MYOCD0.708845505
EML1DCHS10.708417807
EML1HOXA40.707215504
EML1ATP2B40.704453605
EML1SCN4B0.704231404

For details and further investigation, click here