| Full name: epithelial membrane protein 3 | Alias Symbol: YMP | ||
| Type: protein-coding gene | Cytoband: 19q13.33 | ||
| Entrez ID: 2014 | HGNC ID: HGNC:3335 | Ensembl Gene: ENSG00000142227 | OMIM ID: 602335 |
| Drug and gene relationship at DGIdb | |||
Expression of EMP3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EMP3 | 2014 | 203729_at | 0.3088 | 0.7538 | |
| GSE20347 | EMP3 | 2014 | 203729_at | 0.9265 | 0.0060 | |
| GSE23400 | EMP3 | 2014 | 203729_at | 0.3033 | 0.1058 | |
| GSE26886 | EMP3 | 2014 | 203729_at | 1.2814 | 0.0045 | |
| GSE29001 | EMP3 | 2014 | 203729_at | 0.9178 | 0.1308 | |
| GSE38129 | EMP3 | 2014 | 203729_at | 0.3785 | 0.3837 | |
| GSE45670 | EMP3 | 2014 | 203729_at | -0.3929 | 0.3764 | |
| GSE53622 | EMP3 | 2014 | 60619 | 0.3130 | 0.0325 | |
| GSE53624 | EMP3 | 2014 | 60619 | 0.7485 | 0.0000 | |
| GSE63941 | EMP3 | 2014 | 203729_at | -2.0876 | 0.1187 | |
| GSE77861 | EMP3 | 2014 | 203729_at | 0.9863 | 0.1120 | |
| GSE97050 | EMP3 | 2014 | A_23_P119362 | -0.0286 | 0.9261 | |
| SRP007169 | EMP3 | 2014 | RNAseq | 2.3012 | 0.0033 | |
| SRP008496 | EMP3 | 2014 | RNAseq | 2.3654 | 0.0000 | |
| SRP064894 | EMP3 | 2014 | RNAseq | 1.1372 | 0.0114 | |
| SRP133303 | EMP3 | 2014 | RNAseq | 0.8995 | 0.0103 | |
| SRP159526 | EMP3 | 2014 | RNAseq | 0.1439 | 0.5387 | |
| SRP193095 | EMP3 | 2014 | RNAseq | 1.5351 | 0.0000 | |
| SRP219564 | EMP3 | 2014 | RNAseq | 0.7778 | 0.2368 | |
| TCGA | EMP3 | 2014 | RNAseq | 0.0501 | 0.6671 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by EMP3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EMP3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EMP3 | 2014 | 4 | 4 | 22 | |
| GSE20123 | EMP3 | 2014 | 4 | 3 | 23 | |
| GSE43470 | EMP3 | 2014 | 4 | 11 | 28 | |
| GSE46452 | EMP3 | 2014 | 45 | 1 | 13 | |
| GSE47630 | EMP3 | 2014 | 9 | 6 | 25 | |
| GSE54993 | EMP3 | 2014 | 17 | 4 | 49 | |
| GSE54994 | EMP3 | 2014 | 4 | 14 | 35 | |
| GSE60625 | EMP3 | 2014 | 9 | 0 | 2 | |
| GSE74703 | EMP3 | 2014 | 4 | 7 | 25 | |
| GSE74704 | EMP3 | 2014 | 4 | 1 | 15 | |
| TCGA | EMP3 | 2014 | 15 | 19 | 62 |
Total number of gains: 119; Total number of losses: 70; Total Number of normals: 299.
Somatic mutations of EMP3:
Generating mutation plots.
Highly correlated genes for EMP3:
Showing top 20/1184 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EMP3 | LGALS1 | 0.759494 | 13 | 0 | 13 |
| EMP3 | MICAL2 | 0.759027 | 10 | 0 | 10 |
| EMP3 | RFTN2 | 0.74979 | 3 | 0 | 3 |
| EMP3 | RNF19A | 0.728234 | 3 | 0 | 3 |
| EMP3 | COL6A2 | 0.721141 | 13 | 0 | 13 |
| EMP3 | AQP9 | 0.711993 | 3 | 0 | 3 |
| EMP3 | FSTL1 | 0.704985 | 12 | 0 | 10 |
| EMP3 | FBN1 | 0.704876 | 10 | 0 | 9 |
| EMP3 | COL6A1 | 0.702768 | 13 | 0 | 12 |
| EMP3 | VIM | 0.69605 | 12 | 0 | 12 |
| EMP3 | TPCN2 | 0.695351 | 4 | 0 | 4 |
| EMP3 | ITGA5 | 0.694323 | 12 | 0 | 11 |
| EMP3 | RHOBTB1 | 0.693959 | 11 | 0 | 11 |
| EMP3 | KRTCAP2 | 0.693111 | 3 | 0 | 3 |
| EMP3 | AEBP1 | 0.69201 | 12 | 0 | 10 |
| EMP3 | BICC1 | 0.690832 | 10 | 0 | 8 |
| EMP3 | LAMC1 | 0.690704 | 11 | 0 | 10 |
| EMP3 | EFEMP2 | 0.688688 | 13 | 0 | 12 |
| EMP3 | CAV1 | 0.687509 | 12 | 0 | 12 |
| EMP3 | CLMP | 0.687502 | 7 | 0 | 6 |
For details and further investigation, click here
