| Full name: endonuclease domain containing 1 | Alias Symbol: KIAA0830 | ||
| Type: protein-coding gene | Cytoband: 11q21 | ||
| Entrez ID: 23052 | HGNC ID: HGNC:29129 | Ensembl Gene: ENSG00000149218 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ENDOD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ENDOD1 | 23052 | 212573_at | -0.8317 | 0.0895 | |
| GSE20347 | ENDOD1 | 23052 | 212573_at | -0.8537 | 0.0036 | |
| GSE23400 | ENDOD1 | 23052 | 212573_at | -0.3754 | 0.0005 | |
| GSE26886 | ENDOD1 | 23052 | 212573_at | -1.2173 | 0.0001 | |
| GSE29001 | ENDOD1 | 23052 | 212573_at | -0.9195 | 0.0045 | |
| GSE38129 | ENDOD1 | 23052 | 212573_at | -0.6875 | 0.0014 | |
| GSE45670 | ENDOD1 | 23052 | 212573_at | -0.3087 | 0.1657 | |
| GSE53622 | ENDOD1 | 23052 | 59155 | -0.6162 | 0.0000 | |
| GSE53624 | ENDOD1 | 23052 | 59155 | -0.8226 | 0.0000 | |
| GSE63941 | ENDOD1 | 23052 | 212573_at | -1.7322 | 0.0185 | |
| GSE77861 | ENDOD1 | 23052 | 212573_at | -0.4265 | 0.3129 | |
| GSE97050 | ENDOD1 | 23052 | A_24_P189533 | -0.2331 | 0.5788 | |
| SRP007169 | ENDOD1 | 23052 | RNAseq | -1.3807 | 0.0001 | |
| SRP008496 | ENDOD1 | 23052 | RNAseq | -0.3618 | 0.3451 | |
| SRP064894 | ENDOD1 | 23052 | RNAseq | -0.4718 | 0.0024 | |
| SRP133303 | ENDOD1 | 23052 | RNAseq | -0.7345 | 0.0000 | |
| SRP159526 | ENDOD1 | 23052 | RNAseq | -0.5238 | 0.2577 | |
| SRP193095 | ENDOD1 | 23052 | RNAseq | -1.0599 | 0.0000 | |
| SRP219564 | ENDOD1 | 23052 | RNAseq | -0.3562 | 0.4169 | |
| TCGA | ENDOD1 | 23052 | RNAseq | 0.0731 | 0.3747 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by ENDOD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ENDOD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ENDOD1 | 23052 | 3 | 8 | 19 | |
| GSE20123 | ENDOD1 | 23052 | 3 | 8 | 19 | |
| GSE43470 | ENDOD1 | 23052 | 2 | 5 | 36 | |
| GSE46452 | ENDOD1 | 23052 | 5 | 24 | 30 | |
| GSE47630 | ENDOD1 | 23052 | 2 | 19 | 19 | |
| GSE54993 | ENDOD1 | 23052 | 8 | 2 | 60 | |
| GSE54994 | ENDOD1 | 23052 | 6 | 18 | 29 | |
| GSE60625 | ENDOD1 | 23052 | 0 | 3 | 8 | |
| GSE74703 | ENDOD1 | 23052 | 1 | 4 | 31 | |
| GSE74704 | ENDOD1 | 23052 | 3 | 4 | 13 | |
| TCGA | ENDOD1 | 23052 | 11 | 43 | 42 |
Total number of gains: 44; Total number of losses: 138; Total Number of normals: 306.
Somatic mutations of ENDOD1:
Generating mutation plots.
Highly correlated genes for ENDOD1:
Showing top 20/1153 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ENDOD1 | PPM1D | 0.76772 | 3 | 0 | 3 |
| ENDOD1 | SLC16A14 | 0.739253 | 5 | 0 | 4 |
| ENDOD1 | SBF2 | 0.738605 | 3 | 0 | 3 |
| ENDOD1 | WDR20 | 0.72801 | 3 | 0 | 3 |
| ENDOD1 | COG5 | 0.723611 | 3 | 0 | 3 |
| ENDOD1 | VPS29 | 0.722898 | 4 | 0 | 4 |
| ENDOD1 | ZFC3H1 | 0.722132 | 4 | 0 | 3 |
| ENDOD1 | LYSMD3 | 0.721962 | 6 | 0 | 6 |
| ENDOD1 | FAR1 | 0.717954 | 4 | 0 | 3 |
| ENDOD1 | FAM122A | 0.709301 | 4 | 0 | 3 |
| ENDOD1 | PDSS2 | 0.703944 | 4 | 0 | 4 |
| ENDOD1 | PCNT | 0.701197 | 3 | 0 | 3 |
| ENDOD1 | MBOAT1 | 0.701096 | 3 | 0 | 3 |
| ENDOD1 | ANKRA2 | 0.699899 | 3 | 0 | 3 |
| ENDOD1 | FYTTD1 | 0.69878 | 3 | 0 | 3 |
| ENDOD1 | ZNF717 | 0.698309 | 4 | 0 | 3 |
| ENDOD1 | LMAN1 | 0.696536 | 3 | 0 | 3 |
| ENDOD1 | PTGR1 | 0.69627 | 6 | 0 | 4 |
| ENDOD1 | COMTD1 | 0.693126 | 3 | 0 | 3 |
| ENDOD1 | CA5B | 0.692501 | 4 | 0 | 3 |
For details and further investigation, click here
