| Full name: lectin, mannose binding 1 | Alias Symbol: MR60|ERGIC-53|ERGIC53|gp58|MCFD1|FMFD1 | ||
| Type: protein-coding gene | Cytoband: 18q21.32 | ||
| Entrez ID: 3998 | HGNC ID: HGNC:6631 | Ensembl Gene: ENSG00000074695 | OMIM ID: 601567 |
| Drug and gene relationship at DGIdb | |||
Expression of LMAN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LMAN1 | 3998 | 224629_at | 0.0773 | 0.9124 | |
| GSE20347 | LMAN1 | 3998 | 203293_s_at | -0.0791 | 0.4742 | |
| GSE23400 | LMAN1 | 3998 | 203294_s_at | 0.0635 | 0.1556 | |
| GSE26886 | LMAN1 | 3998 | 224629_at | -1.0007 | 0.0001 | |
| GSE29001 | LMAN1 | 3998 | 203293_s_at | -0.2427 | 0.2785 | |
| GSE38129 | LMAN1 | 3998 | 203293_s_at | -0.0269 | 0.7842 | |
| GSE45670 | LMAN1 | 3998 | 224629_at | -0.0857 | 0.5121 | |
| GSE53622 | LMAN1 | 3998 | 45937 | 0.1518 | 0.0849 | |
| GSE53624 | LMAN1 | 3998 | 45937 | 0.0095 | 0.9188 | |
| GSE63941 | LMAN1 | 3998 | 224629_at | -0.9518 | 0.0056 | |
| GSE77861 | LMAN1 | 3998 | 224629_at | 0.0247 | 0.8957 | |
| GSE97050 | LMAN1 | 3998 | A_24_P159702 | 0.4609 | 0.2151 | |
| SRP007169 | LMAN1 | 3998 | RNAseq | -0.4317 | 0.1688 | |
| SRP008496 | LMAN1 | 3998 | RNAseq | -0.1870 | 0.3395 | |
| SRP064894 | LMAN1 | 3998 | RNAseq | 0.2108 | 0.3032 | |
| SRP133303 | LMAN1 | 3998 | RNAseq | 0.1711 | 0.4520 | |
| SRP159526 | LMAN1 | 3998 | RNAseq | 0.1121 | 0.6990 | |
| SRP193095 | LMAN1 | 3998 | RNAseq | -0.2800 | 0.0583 | |
| SRP219564 | LMAN1 | 3998 | RNAseq | -0.2953 | 0.4280 | |
| TCGA | LMAN1 | 3998 | RNAseq | -0.0930 | 0.0351 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by LMAN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LMAN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LMAN1 | 3998 | 1 | 9 | 20 | |
| GSE20123 | LMAN1 | 3998 | 1 | 9 | 20 | |
| GSE43470 | LMAN1 | 3998 | 0 | 5 | 38 | |
| GSE46452 | LMAN1 | 3998 | 1 | 26 | 32 | |
| GSE47630 | LMAN1 | 3998 | 5 | 20 | 15 | |
| GSE54993 | LMAN1 | 3998 | 10 | 0 | 60 | |
| GSE54994 | LMAN1 | 3998 | 0 | 18 | 35 | |
| GSE60625 | LMAN1 | 3998 | 0 | 4 | 7 | |
| GSE74703 | LMAN1 | 3998 | 0 | 5 | 31 | |
| GSE74704 | LMAN1 | 3998 | 1 | 6 | 13 | |
| TCGA | LMAN1 | 3998 | 9 | 44 | 43 |
Total number of gains: 28; Total number of losses: 146; Total Number of normals: 314.
Somatic mutations of LMAN1:
Generating mutation plots.
Highly correlated genes for LMAN1:
Showing top 20/250 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LMAN1 | LZTS1 | 0.855026 | 3 | 0 | 3 |
| LMAN1 | CPVL | 0.796773 | 3 | 0 | 3 |
| LMAN1 | ENC1 | 0.790939 | 3 | 0 | 3 |
| LMAN1 | CYSLTR2 | 0.769307 | 3 | 0 | 3 |
| LMAN1 | PI15 | 0.767441 | 3 | 0 | 3 |
| LMAN1 | ENTPD4 | 0.76557 | 3 | 0 | 3 |
| LMAN1 | IL13RA2 | 0.757775 | 3 | 0 | 3 |
| LMAN1 | EDEM1 | 0.755073 | 3 | 0 | 3 |
| LMAN1 | KCNN1 | 0.743125 | 3 | 0 | 3 |
| LMAN1 | SLFN11 | 0.739354 | 3 | 0 | 3 |
| LMAN1 | FAM162B | 0.73087 | 3 | 0 | 3 |
| LMAN1 | IRAK2 | 0.72936 | 3 | 0 | 3 |
| LMAN1 | GBE1 | 0.723724 | 3 | 0 | 3 |
| LMAN1 | ACVRL1 | 0.722171 | 4 | 0 | 3 |
| LMAN1 | ZNF215 | 0.718982 | 3 | 0 | 3 |
| LMAN1 | CHD2 | 0.71722 | 3 | 0 | 3 |
| LMAN1 | BMP6 | 0.71624 | 3 | 0 | 3 |
| LMAN1 | GPRIN3 | 0.716046 | 3 | 0 | 3 |
| LMAN1 | POU2F2 | 0.715526 | 3 | 0 | 3 |
| LMAN1 | KALRN | 0.711389 | 3 | 0 | 3 |
For details and further investigation, click here
