| Full name: decaprenyl diphosphate synthase subunit 2 | Alias Symbol: bA59I9.3|COQ1B | ||
| Type: protein-coding gene | Cytoband: 6q21 | ||
| Entrez ID: 57107 | HGNC ID: HGNC:23041 | Ensembl Gene: ENSG00000164494 | OMIM ID: 610564 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of PDSS2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PDSS2 | 57107 | 219307_at | -0.2891 | 0.3526 | |
| GSE20347 | PDSS2 | 57107 | 219307_at | -0.1573 | 0.2447 | |
| GSE23400 | PDSS2 | 57107 | 219307_at | -0.0551 | 0.3961 | |
| GSE26886 | PDSS2 | 57107 | 219307_at | -0.5807 | 0.0018 | |
| GSE29001 | PDSS2 | 57107 | 219307_at | -0.2690 | 0.2192 | |
| GSE38129 | PDSS2 | 57107 | 219307_at | -0.1826 | 0.1365 | |
| GSE45670 | PDSS2 | 57107 | 219307_at | -0.0967 | 0.4999 | |
| GSE53622 | PDSS2 | 57107 | 12406 | -0.1785 | 0.0190 | |
| GSE53624 | PDSS2 | 57107 | 67799 | -0.4896 | 0.0000 | |
| GSE63941 | PDSS2 | 57107 | 219307_at | -0.7676 | 0.1529 | |
| GSE77861 | PDSS2 | 57107 | 219307_at | -0.0885 | 0.6858 | |
| GSE97050 | PDSS2 | 57107 | A_33_P3214456 | 0.3303 | 0.2151 | |
| SRP007169 | PDSS2 | 57107 | RNAseq | -0.9452 | 0.0161 | |
| SRP008496 | PDSS2 | 57107 | RNAseq | -1.1520 | 0.0000 | |
| SRP064894 | PDSS2 | 57107 | RNAseq | -0.2431 | 0.0669 | |
| SRP133303 | PDSS2 | 57107 | RNAseq | -0.1295 | 0.2807 | |
| SRP159526 | PDSS2 | 57107 | RNAseq | -0.4707 | 0.0157 | |
| SRP193095 | PDSS2 | 57107 | RNAseq | -0.5096 | 0.0000 | |
| SRP219564 | PDSS2 | 57107 | RNAseq | -0.1687 | 0.5867 | |
| TCGA | PDSS2 | 57107 | RNAseq | -0.2125 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PDSS2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PDSS2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PDSS2 | 57107 | 2 | 3 | 25 | |
| GSE20123 | PDSS2 | 57107 | 2 | 2 | 26 | |
| GSE43470 | PDSS2 | 57107 | 3 | 1 | 39 | |
| GSE46452 | PDSS2 | 57107 | 2 | 11 | 46 | |
| GSE47630 | PDSS2 | 57107 | 9 | 4 | 27 | |
| GSE54993 | PDSS2 | 57107 | 3 | 2 | 65 | |
| GSE54994 | PDSS2 | 57107 | 8 | 12 | 33 | |
| GSE60625 | PDSS2 | 57107 | 0 | 2 | 9 | |
| GSE74703 | PDSS2 | 57107 | 2 | 1 | 33 | |
| GSE74704 | PDSS2 | 57107 | 0 | 0 | 20 | |
| TCGA | PDSS2 | 57107 | 5 | 23 | 68 |
Total number of gains: 36; Total number of losses: 61; Total Number of normals: 391.
Somatic mutations of PDSS2:
Generating mutation plots.
Highly correlated genes for PDSS2:
Showing top 20/522 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PDSS2 | TMED10 | 0.797959 | 3 | 0 | 3 |
| PDSS2 | VAMP5 | 0.742583 | 3 | 0 | 3 |
| PDSS2 | HOOK3 | 0.733784 | 3 | 0 | 3 |
| PDSS2 | SLC12A6 | 0.732262 | 3 | 0 | 3 |
| PDSS2 | SERPINB9 | 0.731492 | 3 | 0 | 3 |
| PDSS2 | RPL41 | 0.710925 | 3 | 0 | 3 |
| PDSS2 | ENDOD1 | 0.703944 | 4 | 0 | 4 |
| PDSS2 | QRICH1 | 0.702681 | 3 | 0 | 3 |
| PDSS2 | CHMP5 | 0.691901 | 4 | 0 | 4 |
| PDSS2 | SYTL5 | 0.689754 | 3 | 0 | 3 |
| PDSS2 | PPP2CB | 0.689133 | 4 | 0 | 3 |
| PDSS2 | ACTR1A | 0.687411 | 3 | 0 | 3 |
| PDSS2 | TSPAN31 | 0.680816 | 3 | 0 | 3 |
| PDSS2 | LYSMD3 | 0.677611 | 4 | 0 | 4 |
| PDSS2 | ZRANB1 | 0.671144 | 3 | 0 | 3 |
| PDSS2 | ARPC5 | 0.67062 | 3 | 0 | 3 |
| PDSS2 | NDUFS2 | 0.66992 | 3 | 0 | 3 |
| PDSS2 | TBCK | 0.666909 | 4 | 0 | 3 |
| PDSS2 | GBE1 | 0.665905 | 3 | 0 | 3 |
| PDSS2 | ALDH1A3 | 0.662572 | 4 | 0 | 4 |
For details and further investigation, click here
