| Full name: eomesodermin | Alias Symbol: TBR2 | ||
| Type: protein-coding gene | Cytoband: 3p24.1 | ||
| Entrez ID: 8320 | HGNC ID: HGNC:3372 | Ensembl Gene: ENSG00000163508 | OMIM ID: 604615 |
| Drug and gene relationship at DGIdb | |||
Expression of EOMES:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EOMES | 8320 | 231776_at | 0.4973 | 0.5935 | |
| GSE26886 | EOMES | 8320 | 231776_at | 0.0646 | 0.6865 | |
| GSE45670 | EOMES | 8320 | 231776_at | 0.0379 | 0.8976 | |
| GSE53622 | EOMES | 8320 | 33361 | 0.5509 | 0.0166 | |
| GSE53624 | EOMES | 8320 | 33361 | 0.7461 | 0.0001 | |
| GSE63941 | EOMES | 8320 | 231776_at | 0.6658 | 0.2894 | |
| GSE77861 | EOMES | 8320 | 231776_at | 0.0910 | 0.4897 | |
| SRP133303 | EOMES | 8320 | RNAseq | -0.2371 | 0.5149 | |
| SRP159526 | EOMES | 8320 | RNAseq | -0.2488 | 0.6136 | |
| SRP219564 | EOMES | 8320 | RNAseq | 1.3069 | 0.0299 | |
| TCGA | EOMES | 8320 | RNAseq | 0.6036 | 0.0507 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by EOMES expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EOMES:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EOMES | 8320 | 0 | 18 | 12 | |
| GSE20123 | EOMES | 8320 | 0 | 18 | 12 | |
| GSE43470 | EOMES | 8320 | 0 | 20 | 23 | |
| GSE46452 | EOMES | 8320 | 2 | 17 | 40 | |
| GSE47630 | EOMES | 8320 | 1 | 24 | 15 | |
| GSE54993 | EOMES | 8320 | 6 | 2 | 62 | |
| GSE54994 | EOMES | 8320 | 1 | 32 | 20 | |
| GSE60625 | EOMES | 8320 | 5 | 0 | 6 | |
| GSE74703 | EOMES | 8320 | 0 | 17 | 19 | |
| GSE74704 | EOMES | 8320 | 0 | 12 | 8 | |
| TCGA | EOMES | 8320 | 2 | 68 | 26 |
Total number of gains: 17; Total number of losses: 228; Total Number of normals: 243.
Somatic mutations of EOMES:
Generating mutation plots.
Highly correlated genes for EOMES:
Showing top 20/137 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EOMES | GZMA | 0.6817 | 3 | 0 | 3 |
| EOMES | HLA-F | 0.663038 | 3 | 0 | 3 |
| EOMES | CYFIP2 | 0.656623 | 3 | 0 | 3 |
| EOMES | JAK3 | 0.650765 | 3 | 0 | 3 |
| EOMES | LILRB4 | 0.649446 | 3 | 0 | 3 |
| EOMES | PSMB8-AS1 | 0.648883 | 4 | 0 | 3 |
| EOMES | SNX20 | 0.648346 | 4 | 0 | 4 |
| EOMES | SH2D1A | 0.647267 | 4 | 0 | 3 |
| EOMES | KIF21B | 0.64687 | 3 | 0 | 3 |
| EOMES | CXorf21 | 0.642939 | 4 | 0 | 3 |
| EOMES | BTN2A2 | 0.639923 | 3 | 0 | 3 |
| EOMES | SIGLEC10 | 0.638684 | 4 | 0 | 3 |
| EOMES | PCED1B | 0.637946 | 3 | 0 | 3 |
| EOMES | PRF1 | 0.637817 | 3 | 0 | 3 |
| EOMES | TIGIT | 0.633965 | 4 | 0 | 3 |
| EOMES | C2 | 0.633844 | 3 | 0 | 3 |
| EOMES | TRAT1 | 0.630421 | 4 | 0 | 3 |
| EOMES | SAMD3 | 0.62971 | 5 | 0 | 3 |
| EOMES | PDE7A | 0.627504 | 3 | 0 | 3 |
| EOMES | BTN3A2 | 0.627267 | 3 | 0 | 3 |
For details and further investigation, click here
