| Full name: G-rich RNA sequence binding factor 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 4q13.3 | ||
| Entrez ID: 2926 | HGNC ID: HGNC:4610 | Ensembl Gene: ENSG00000132463 | OMIM ID: 604851 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of GRSF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GRSF1 | 2926 | 201520_s_at | 0.2817 | 0.5100 | |
| GSE20347 | GRSF1 | 2926 | 201520_s_at | 0.0277 | 0.8741 | |
| GSE23400 | GRSF1 | 2926 | 201520_s_at | 0.4471 | 0.0000 | |
| GSE26886 | GRSF1 | 2926 | 201501_s_at | -0.2006 | 0.3689 | |
| GSE29001 | GRSF1 | 2926 | 201501_s_at | -0.0297 | 0.8858 | |
| GSE38129 | GRSF1 | 2926 | 201520_s_at | 0.2003 | 0.1727 | |
| GSE45670 | GRSF1 | 2926 | 201520_s_at | 0.0709 | 0.6234 | |
| GSE63941 | GRSF1 | 2926 | 201520_s_at | -0.0576 | 0.9108 | |
| GSE77861 | GRSF1 | 2926 | 201520_s_at | 0.0029 | 0.9953 | |
| SRP007169 | GRSF1 | 2926 | RNAseq | -0.3456 | 0.3991 | |
| SRP008496 | GRSF1 | 2926 | RNAseq | -0.3520 | 0.1447 | |
| SRP064894 | GRSF1 | 2926 | RNAseq | 0.0170 | 0.9047 | |
| SRP133303 | GRSF1 | 2926 | RNAseq | 0.2711 | 0.0924 | |
| SRP159526 | GRSF1 | 2926 | RNAseq | 0.0336 | 0.8587 | |
| SRP193095 | GRSF1 | 2926 | RNAseq | -0.1080 | 0.2656 | |
| SRP219564 | GRSF1 | 2926 | RNAseq | -0.4421 | 0.0643 | |
| TCGA | GRSF1 | 2926 | RNAseq | -0.0680 | 0.1153 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GRSF1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of GRSF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GRSF1 | 2926 | 0 | 11 | 19 | |
| GSE20123 | GRSF1 | 2926 | 0 | 11 | 19 | |
| GSE43470 | GRSF1 | 2926 | 0 | 13 | 30 | |
| GSE46452 | GRSF1 | 2926 | 2 | 35 | 22 | |
| GSE47630 | GRSF1 | 2926 | 1 | 19 | 20 | |
| GSE54993 | GRSF1 | 2926 | 7 | 0 | 63 | |
| GSE54994 | GRSF1 | 2926 | 1 | 9 | 43 | |
| GSE60625 | GRSF1 | 2926 | 0 | 0 | 11 | |
| GSE74703 | GRSF1 | 2926 | 0 | 11 | 25 | |
| GSE74704 | GRSF1 | 2926 | 0 | 6 | 14 | |
| TCGA | GRSF1 | 2926 | 16 | 28 | 52 |
Total number of gains: 27; Total number of losses: 143; Total Number of normals: 318.
Somatic mutations of GRSF1:
Generating mutation plots.
Highly correlated genes for GRSF1:
Showing top 20/73 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GRSF1 | ERLIN2 | 0.691726 | 3 | 0 | 3 |
| GRSF1 | TUFM | 0.64742 | 4 | 0 | 3 |
| GRSF1 | FRS2 | 0.63173 | 3 | 0 | 3 |
| GRSF1 | SBNO1 | 0.630545 | 3 | 0 | 3 |
| GRSF1 | MRPL42 | 0.620922 | 5 | 0 | 4 |
| GRSF1 | GEMIN2 | 0.620242 | 3 | 0 | 3 |
| GRSF1 | TM2D2 | 0.610495 | 3 | 0 | 3 |
| GRSF1 | GLO1 | 0.606989 | 4 | 0 | 3 |
| GRSF1 | AP5M1 | 0.606447 | 3 | 0 | 3 |
| GRSF1 | GTF2E2 | 0.603737 | 3 | 0 | 3 |
| GRSF1 | USP1 | 0.599952 | 5 | 0 | 4 |
| GRSF1 | EIF2B1 | 0.598486 | 5 | 0 | 4 |
| GRSF1 | POP5 | 0.594669 | 4 | 0 | 3 |
| GRSF1 | B3GNTL1 | 0.592282 | 3 | 0 | 3 |
| GRSF1 | EIF4A3 | 0.582523 | 5 | 0 | 4 |
| GRSF1 | SLC25A3 | 0.581557 | 5 | 0 | 4 |
| GRSF1 | NUP54 | 0.581055 | 7 | 0 | 6 |
| GRSF1 | SYPL1 | 0.57367 | 4 | 0 | 3 |
| GRSF1 | ATXN10 | 0.559468 | 5 | 0 | 4 |
| GRSF1 | MPHOSPH9 | 0.559056 | 5 | 0 | 3 |
For details and further investigation, click here
