| Full name: ethanolamine kinase 1 | Alias Symbol: EKI1|EKI | ||
| Type: protein-coding gene | Cytoband: 12p12.1 | ||
| Entrez ID: 55500 | HGNC ID: HGNC:24649 | Ensembl Gene: ENSG00000139163 | OMIM ID: 609858 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ETNK1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ETNK1 | 55500 | 219017_at | 0.6243 | 0.1185 | |
| GSE20347 | ETNK1 | 55500 | 219017_at | 0.4447 | 0.1192 | |
| GSE23400 | ETNK1 | 55500 | 219017_at | 0.2900 | 0.0505 | |
| GSE26886 | ETNK1 | 55500 | 219017_at | 0.5391 | 0.1004 | |
| GSE29001 | ETNK1 | 55500 | 219017_at | 0.0795 | 0.8700 | |
| GSE38129 | ETNK1 | 55500 | 219017_at | 0.6757 | 0.0083 | |
| GSE45670 | ETNK1 | 55500 | 219017_at | 0.5690 | 0.0105 | |
| GSE53622 | ETNK1 | 55500 | 44808 | 0.3380 | 0.0000 | |
| GSE53624 | ETNK1 | 55500 | 59138 | 0.0034 | 0.9689 | |
| GSE63941 | ETNK1 | 55500 | 219017_at | -0.3894 | 0.6371 | |
| GSE77861 | ETNK1 | 55500 | 225290_at | 0.6409 | 0.2768 | |
| GSE97050 | ETNK1 | 55500 | A_23_P419239 | 0.2649 | 0.3599 | |
| SRP007169 | ETNK1 | 55500 | RNAseq | 0.4698 | 0.1121 | |
| SRP008496 | ETNK1 | 55500 | RNAseq | 0.9490 | 0.0018 | |
| SRP064894 | ETNK1 | 55500 | RNAseq | -0.1732 | 0.4762 | |
| SRP133303 | ETNK1 | 55500 | RNAseq | 0.3419 | 0.1016 | |
| SRP159526 | ETNK1 | 55500 | RNAseq | -0.1059 | 0.6719 | |
| SRP193095 | ETNK1 | 55500 | RNAseq | -0.5509 | 0.0067 | |
| SRP219564 | ETNK1 | 55500 | RNAseq | -0.2256 | 0.4364 | |
| TCGA | ETNK1 | 55500 | RNAseq | -0.2197 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ETNK1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ETNK1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ETNK1 | 55500 | 10 | 1 | 19 | |
| GSE20123 | ETNK1 | 55500 | 10 | 1 | 19 | |
| GSE43470 | ETNK1 | 55500 | 9 | 4 | 30 | |
| GSE46452 | ETNK1 | 55500 | 10 | 1 | 48 | |
| GSE47630 | ETNK1 | 55500 | 14 | 1 | 25 | |
| GSE54993 | ETNK1 | 55500 | 1 | 9 | 60 | |
| GSE54994 | ETNK1 | 55500 | 11 | 2 | 40 | |
| GSE60625 | ETNK1 | 55500 | 0 | 1 | 10 | |
| GSE74703 | ETNK1 | 55500 | 9 | 3 | 24 | |
| GSE74704 | ETNK1 | 55500 | 6 | 1 | 13 | |
| TCGA | ETNK1 | 55500 | 43 | 5 | 48 |
Total number of gains: 123; Total number of losses: 29; Total Number of normals: 336.
Somatic mutations of ETNK1:
Generating mutation plots.
Highly correlated genes for ETNK1:
Showing top 20/453 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ETNK1 | TULP4 | 0.806037 | 3 | 0 | 3 |
| ETNK1 | TAP1 | 0.731511 | 3 | 0 | 3 |
| ETNK1 | BRI3BP | 0.724349 | 3 | 0 | 3 |
| ETNK1 | THADA | 0.723216 | 3 | 0 | 3 |
| ETNK1 | ALG2 | 0.720816 | 3 | 0 | 3 |
| ETNK1 | PPP1R14B | 0.718847 | 3 | 0 | 3 |
| ETNK1 | CLDN1 | 0.71034 | 3 | 0 | 3 |
| ETNK1 | NACC1 | 0.683747 | 3 | 0 | 3 |
| ETNK1 | ERCC6 | 0.680499 | 3 | 0 | 3 |
| ETNK1 | MTRR | 0.672043 | 3 | 0 | 3 |
| ETNK1 | HMGA1 | 0.669759 | 5 | 0 | 4 |
| ETNK1 | NUP43 | 0.664333 | 4 | 0 | 3 |
| ETNK1 | CCNK | 0.662131 | 3 | 0 | 3 |
| ETNK1 | RNF4 | 0.660122 | 3 | 0 | 3 |
| ETNK1 | NCBP2 | 0.656615 | 3 | 0 | 3 |
| ETNK1 | ANKIB1 | 0.655701 | 3 | 0 | 3 |
| ETNK1 | ZNF680 | 0.654714 | 3 | 0 | 3 |
| ETNK1 | KLHL8 | 0.65289 | 3 | 0 | 3 |
| ETNK1 | SLC25A19 | 0.652402 | 3 | 0 | 3 |
| ETNK1 | NADSYN1 | 0.638024 | 4 | 0 | 4 |
For details and further investigation, click here
