| Full name: ALS2 C-terminal like | Alias Symbol: FLJ36525|RN49018|DKFZp686I0110 | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 259173 | HGNC ID: HGNC:20605 | Ensembl Gene: ENSG00000178038 | OMIM ID: 612402 |
| Drug and gene relationship at DGIdb | |||
Expression of ALS2CL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ALS2CL | 259173 | 222333_at | -1.0788 | 0.1474 | |
| GSE20347 | ALS2CL | 259173 | 222333_at | -1.4657 | 0.0000 | |
| GSE23400 | ALS2CL | 259173 | 222333_at | -0.7829 | 0.0000 | |
| GSE26886 | ALS2CL | 259173 | 222333_at | -1.0180 | 0.0000 | |
| GSE29001 | ALS2CL | 259173 | 222333_at | -1.3975 | 0.0000 | |
| GSE38129 | ALS2CL | 259173 | 222333_at | -1.2605 | 0.0000 | |
| GSE45670 | ALS2CL | 259173 | 222333_at | -0.4113 | 0.1043 | |
| GSE53622 | ALS2CL | 259173 | 93012 | -1.6271 | 0.0000 | |
| GSE53624 | ALS2CL | 259173 | 93012 | -1.7256 | 0.0000 | |
| GSE63941 | ALS2CL | 259173 | 229887_at | 0.8407 | 0.0160 | |
| GSE77861 | ALS2CL | 259173 | 222333_at | -0.7247 | 0.0029 | |
| GSE97050 | ALS2CL | 259173 | A_32_P420009 | -0.3108 | 0.4863 | |
| SRP007169 | ALS2CL | 259173 | RNAseq | -3.6293 | 0.0000 | |
| SRP008496 | ALS2CL | 259173 | RNAseq | -3.1207 | 0.0000 | |
| SRP064894 | ALS2CL | 259173 | RNAseq | -1.9947 | 0.0000 | |
| SRP133303 | ALS2CL | 259173 | RNAseq | -2.2527 | 0.0000 | |
| SRP159526 | ALS2CL | 259173 | RNAseq | -2.9742 | 0.0000 | |
| SRP193095 | ALS2CL | 259173 | RNAseq | -1.7987 | 0.0000 | |
| SRP219564 | ALS2CL | 259173 | RNAseq | -1.6590 | 0.0561 | |
| TCGA | ALS2CL | 259173 | RNAseq | 0.0301 | 0.8314 |
Upregulated datasets: 0; Downregulated datasets: 12.
Survival by ALS2CL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ALS2CL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ALS2CL | 259173 | 0 | 18 | 12 | |
| GSE20123 | ALS2CL | 259173 | 0 | 19 | 11 | |
| GSE43470 | ALS2CL | 259173 | 0 | 19 | 24 | |
| GSE46452 | ALS2CL | 259173 | 2 | 17 | 40 | |
| GSE47630 | ALS2CL | 259173 | 2 | 23 | 15 | |
| GSE54993 | ALS2CL | 259173 | 7 | 2 | 61 | |
| GSE54994 | ALS2CL | 259173 | 0 | 36 | 17 | |
| GSE60625 | ALS2CL | 259173 | 5 | 0 | 6 | |
| GSE74703 | ALS2CL | 259173 | 0 | 15 | 21 | |
| GSE74704 | ALS2CL | 259173 | 0 | 12 | 8 | |
| TCGA | ALS2CL | 259173 | 1 | 75 | 20 |
Total number of gains: 17; Total number of losses: 236; Total Number of normals: 235.
Somatic mutations of ALS2CL:
Generating mutation plots.
Highly correlated genes for ALS2CL:
Showing top 20/1504 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ALS2CL | CWH43 | 0.844951 | 10 | 0 | 10 |
| ALS2CL | PPDPF | 0.839704 | 9 | 0 | 9 |
| ALS2CL | SH3GL1 | 0.839037 | 10 | 0 | 10 |
| ALS2CL | PADI1 | 0.835796 | 9 | 0 | 9 |
| ALS2CL | TMOD3 | 0.827864 | 10 | 0 | 10 |
| ALS2CL | PIM1 | 0.826636 | 10 | 0 | 10 |
| ALS2CL | MXD1 | 0.820956 | 11 | 0 | 10 |
| ALS2CL | SCNN1B | 0.817288 | 11 | 0 | 11 |
| ALS2CL | DHRS1 | 0.816204 | 12 | 0 | 12 |
| ALS2CL | GYS2 | 0.815565 | 10 | 0 | 10 |
| ALS2CL | GDPD3 | 0.81412 | 12 | 0 | 12 |
| ALS2CL | RNF222 | 0.810955 | 3 | 0 | 3 |
| ALS2CL | CXCR2 | 0.810907 | 10 | 0 | 10 |
| ALS2CL | EPS8L2 | 0.810473 | 12 | 0 | 11 |
| ALS2CL | VSIG10L | 0.808453 | 7 | 0 | 7 |
| ALS2CL | PTK6 | 0.807765 | 13 | 0 | 12 |
| ALS2CL | EVPL | 0.80564 | 13 | 0 | 13 |
| ALS2CL | TOM1 | 0.804117 | 11 | 0 | 11 |
| ALS2CL | TTC9 | 0.797732 | 10 | 0 | 10 |
| ALS2CL | TMEM40 | 0.797725 | 12 | 0 | 12 |
For details and further investigation, click here
