| Full name: family with sequence similarity 114 member A2 | Alias Symbol: 133K02 | ||
| Type: protein-coding gene | Cytoband: 5q33.2 | ||
| Entrez ID: 10827 | HGNC ID: HGNC:1333 | Ensembl Gene: ENSG00000055147 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of FAM114A2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM114A2 | 10827 | 222682_s_at | -0.7008 | 0.1301 | |
| GSE20347 | FAM114A2 | 10827 | 218588_s_at | -0.6068 | 0.0000 | |
| GSE23400 | FAM114A2 | 10827 | 218588_s_at | -0.2228 | 0.0000 | |
| GSE26886 | FAM114A2 | 10827 | 218588_s_at | -1.2691 | 0.0000 | |
| GSE29001 | FAM114A2 | 10827 | 218588_s_at | -0.6004 | 0.0042 | |
| GSE38129 | FAM114A2 | 10827 | 218588_s_at | -0.6699 | 0.0000 | |
| GSE45670 | FAM114A2 | 10827 | 218588_s_at | -0.3150 | 0.0518 | |
| GSE53622 | FAM114A2 | 10827 | 126950 | -0.5819 | 0.0000 | |
| GSE53624 | FAM114A2 | 10827 | 126950 | -0.7440 | 0.0000 | |
| GSE63941 | FAM114A2 | 10827 | 222682_s_at | -0.6396 | 0.4885 | |
| GSE77861 | FAM114A2 | 10827 | 222682_s_at | -0.7573 | 0.0173 | |
| GSE97050 | FAM114A2 | 10827 | A_23_P41908 | 0.2030 | 0.3907 | |
| SRP007169 | FAM114A2 | 10827 | RNAseq | -1.2352 | 0.0023 | |
| SRP008496 | FAM114A2 | 10827 | RNAseq | -1.1227 | 0.0000 | |
| SRP064894 | FAM114A2 | 10827 | RNAseq | -0.2957 | 0.0248 | |
| SRP133303 | FAM114A2 | 10827 | RNAseq | -0.4455 | 0.0084 | |
| SRP159526 | FAM114A2 | 10827 | RNAseq | -0.7097 | 0.0154 | |
| SRP193095 | FAM114A2 | 10827 | RNAseq | -0.8202 | 0.0000 | |
| SRP219564 | FAM114A2 | 10827 | RNAseq | -0.3621 | 0.1071 | |
| TCGA | FAM114A2 | 10827 | RNAseq | -0.2905 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by FAM114A2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM114A2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM114A2 | 10827 | 0 | 12 | 18 | |
| GSE20123 | FAM114A2 | 10827 | 0 | 12 | 18 | |
| GSE43470 | FAM114A2 | 10827 | 2 | 10 | 31 | |
| GSE46452 | FAM114A2 | 10827 | 0 | 27 | 32 | |
| GSE47630 | FAM114A2 | 10827 | 0 | 20 | 20 | |
| GSE54993 | FAM114A2 | 10827 | 9 | 1 | 60 | |
| GSE54994 | FAM114A2 | 10827 | 1 | 16 | 36 | |
| GSE60625 | FAM114A2 | 10827 | 0 | 0 | 11 | |
| GSE74703 | FAM114A2 | 10827 | 2 | 8 | 26 | |
| GSE74704 | FAM114A2 | 10827 | 0 | 7 | 13 | |
| TCGA | FAM114A2 | 10827 | 5 | 37 | 54 |
Total number of gains: 19; Total number of losses: 150; Total Number of normals: 319.
Somatic mutations of FAM114A2:
Generating mutation plots.
Highly correlated genes for FAM114A2:
Showing top 20/1417 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM114A2 | EXOC6B | 0.812767 | 3 | 0 | 3 |
| FAM114A2 | ZNF844 | 0.784934 | 4 | 0 | 4 |
| FAM114A2 | SRP68 | 0.779937 | 3 | 0 | 3 |
| FAM114A2 | PPIL3 | 0.76933 | 3 | 0 | 3 |
| FAM114A2 | UBQLN1 | 0.758489 | 3 | 0 | 3 |
| FAM114A2 | GOLGA4 | 0.738886 | 8 | 0 | 8 |
| FAM114A2 | FBXO8 | 0.732484 | 7 | 0 | 7 |
| FAM114A2 | MTMR9 | 0.731012 | 3 | 0 | 3 |
| FAM114A2 | STX12 | 0.721627 | 11 | 0 | 10 |
| FAM114A2 | DLL1 | 0.718191 | 3 | 0 | 3 |
| FAM114A2 | NCKAP1 | 0.71807 | 4 | 0 | 3 |
| FAM114A2 | RHBDF1 | 0.71785 | 6 | 0 | 5 |
| FAM114A2 | CRK | 0.71195 | 3 | 0 | 3 |
| FAM114A2 | MAML2 | 0.711643 | 3 | 0 | 3 |
| FAM114A2 | TOM1L1 | 0.70915 | 4 | 0 | 3 |
| FAM114A2 | CPEB4 | 0.708921 | 7 | 0 | 7 |
| FAM114A2 | KAT2B | 0.708801 | 11 | 0 | 11 |
| FAM114A2 | MFAP3 | 0.708375 | 10 | 0 | 10 |
| FAM114A2 | RBM20 | 0.706418 | 4 | 0 | 4 |
| FAM114A2 | TMEM234 | 0.705917 | 3 | 0 | 3 |
For details and further investigation, click here
