| Full name: syntaxin 12 | Alias Symbol: STX13|STX14 | ||
| Type: protein-coding gene | Cytoband: 1p35.3 | ||
| Entrez ID: 23673 | HGNC ID: HGNC:11430 | Ensembl Gene: ENSG00000117758 | OMIM ID: 606892 |
| Drug and gene relationship at DGIdb | |||
Expression of STX12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STX12 | 23673 | 212112_s_at | -0.7541 | 0.0872 | |
| GSE20347 | STX12 | 23673 | 212112_s_at | -1.4534 | 0.0000 | |
| GSE23400 | STX12 | 23673 | 212112_s_at | -0.6911 | 0.0000 | |
| GSE26886 | STX12 | 23673 | 212112_s_at | -1.6580 | 0.0000 | |
| GSE29001 | STX12 | 23673 | 212112_s_at | -1.2141 | 0.0001 | |
| GSE38129 | STX12 | 23673 | 212112_s_at | -1.2027 | 0.0000 | |
| GSE45670 | STX12 | 23673 | 212112_s_at | -0.5794 | 0.0082 | |
| GSE53622 | STX12 | 23673 | 68947 | -0.5994 | 0.0000 | |
| GSE53624 | STX12 | 23673 | 68947 | -0.5903 | 0.0000 | |
| GSE63941 | STX12 | 23673 | 212112_s_at | -1.6772 | 0.0009 | |
| GSE77861 | STX12 | 23673 | 212112_s_at | -1.2557 | 0.0002 | |
| GSE97050 | STX12 | 23673 | A_23_P385206 | -0.1945 | 0.4577 | |
| SRP007169 | STX12 | 23673 | RNAseq | -1.6621 | 0.0000 | |
| SRP008496 | STX12 | 23673 | RNAseq | -1.5965 | 0.0000 | |
| SRP064894 | STX12 | 23673 | RNAseq | -0.8205 | 0.0000 | |
| SRP133303 | STX12 | 23673 | RNAseq | -0.5966 | 0.0009 | |
| SRP159526 | STX12 | 23673 | RNAseq | -1.2548 | 0.0000 | |
| SRP193095 | STX12 | 23673 | RNAseq | -1.1203 | 0.0000 | |
| SRP219564 | STX12 | 23673 | RNAseq | -0.9452 | 0.0044 | |
| TCGA | STX12 | 23673 | RNAseq | -0.5263 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 10.
Survival by STX12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of STX12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STX12 | 23673 | 0 | 6 | 24 | |
| GSE20123 | STX12 | 23673 | 0 | 5 | 25 | |
| GSE43470 | STX12 | 23673 | 3 | 6 | 34 | |
| GSE46452 | STX12 | 23673 | 5 | 1 | 53 | |
| GSE47630 | STX12 | 23673 | 8 | 3 | 29 | |
| GSE54993 | STX12 | 23673 | 2 | 1 | 67 | |
| GSE54994 | STX12 | 23673 | 10 | 4 | 39 | |
| GSE60625 | STX12 | 23673 | 0 | 0 | 11 | |
| GSE74703 | STX12 | 23673 | 2 | 4 | 30 | |
| GSE74704 | STX12 | 23673 | 0 | 0 | 20 | |
| TCGA | STX12 | 23673 | 11 | 23 | 62 |
Total number of gains: 41; Total number of losses: 53; Total Number of normals: 394.
Somatic mutations of STX12:
Generating mutation plots.
Highly correlated genes for STX12:
Showing top 20/1608 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STX12 | SFTA2 | 0.839215 | 4 | 0 | 4 |
| STX12 | CLIC3 | 0.832947 | 8 | 0 | 8 |
| STX12 | SNORA68 | 0.805007 | 4 | 0 | 4 |
| STX12 | KAT2B | 0.795033 | 12 | 0 | 11 |
| STX12 | SPAG17 | 0.794553 | 4 | 0 | 4 |
| STX12 | ACOX1 | 0.794144 | 10 | 0 | 10 |
| STX12 | CXCR2 | 0.792244 | 11 | 0 | 11 |
| STX12 | ECM1 | 0.782149 | 11 | 0 | 10 |
| STX12 | CPPED1 | 0.77431 | 11 | 0 | 10 |
| STX12 | PSCA | 0.772809 | 8 | 0 | 8 |
| STX12 | CWH43 | 0.768989 | 10 | 0 | 9 |
| STX12 | PPP1R3C | 0.768788 | 12 | 0 | 12 |
| STX12 | HPGD | 0.767268 | 11 | 0 | 10 |
| STX12 | GDPD3 | 0.764668 | 10 | 0 | 9 |
| STX12 | RANBP9 | 0.764432 | 10 | 0 | 9 |
| STX12 | ACAA1 | 0.762013 | 10 | 0 | 10 |
| STX12 | ALDH9A1 | 0.761099 | 11 | 0 | 11 |
| STX12 | LRRFIP2 | 0.757512 | 12 | 0 | 12 |
| STX12 | SMDT1 | 0.756508 | 4 | 0 | 4 |
| STX12 | TP53I3 | 0.75608 | 11 | 0 | 11 |
For details and further investigation, click here
