| Full name: FAM20A golgi associated secretory pathway pseudokinase | Alias Symbol: DKFZp434F2322 | ||
| Type: protein-coding gene | Cytoband: 17q24.2 | ||
| Entrez ID: 54757 | HGNC ID: HGNC:23015 | Ensembl Gene: ENSG00000108950 | OMIM ID: 611062 |
| Drug and gene relationship at DGIdb | |||
Expression of FAM20A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM20A | 54757 | 226804_at | 1.3540 | 0.3182 | |
| GSE26886 | FAM20A | 54757 | 242945_at | -0.2750 | 0.3067 | |
| GSE45670 | FAM20A | 54757 | 226804_at | 0.7667 | 0.0310 | |
| GSE53622 | FAM20A | 54757 | 46488 | 0.6657 | 0.0000 | |
| GSE53624 | FAM20A | 54757 | 46488 | 0.5885 | 0.0000 | |
| GSE63941 | FAM20A | 54757 | 226804_at | -0.3199 | 0.1220 | |
| GSE77861 | FAM20A | 54757 | 242945_at | -0.0443 | 0.7573 | |
| GSE97050 | FAM20A | 54757 | A_32_P108254 | 0.2559 | 0.6443 | |
| SRP007169 | FAM20A | 54757 | RNAseq | 0.5064 | 0.4613 | |
| SRP064894 | FAM20A | 54757 | RNAseq | 1.6641 | 0.0000 | |
| SRP133303 | FAM20A | 54757 | RNAseq | 0.4147 | 0.0230 | |
| SRP159526 | FAM20A | 54757 | RNAseq | 0.1918 | 0.4992 | |
| SRP193095 | FAM20A | 54757 | RNAseq | 0.3383 | 0.1263 | |
| SRP219564 | FAM20A | 54757 | RNAseq | 1.7632 | 0.0011 | |
| TCGA | FAM20A | 54757 | RNAseq | -0.4783 | 0.0051 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by FAM20A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM20A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM20A | 54757 | 3 | 2 | 25 | |
| GSE20123 | FAM20A | 54757 | 3 | 2 | 25 | |
| GSE43470 | FAM20A | 54757 | 5 | 0 | 38 | |
| GSE46452 | FAM20A | 54757 | 31 | 1 | 27 | |
| GSE47630 | FAM20A | 54757 | 7 | 1 | 32 | |
| GSE54993 | FAM20A | 54757 | 2 | 5 | 63 | |
| GSE54994 | FAM20A | 54757 | 9 | 4 | 40 | |
| GSE60625 | FAM20A | 54757 | 4 | 3 | 4 | |
| GSE74703 | FAM20A | 54757 | 5 | 0 | 31 | |
| GSE74704 | FAM20A | 54757 | 3 | 1 | 16 | |
| TCGA | FAM20A | 54757 | 28 | 9 | 59 |
Total number of gains: 100; Total number of losses: 28; Total Number of normals: 360.
Somatic mutations of FAM20A:
Generating mutation plots.
Highly correlated genes for FAM20A:
Showing top 20/59 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM20A | TCIRG1 | 0.745797 | 3 | 0 | 3 |
| FAM20A | FCER1G | 0.663188 | 3 | 0 | 3 |
| FAM20A | NDFIP1 | 0.649703 | 3 | 0 | 3 |
| FAM20A | PLXND1 | 0.618206 | 4 | 0 | 3 |
| FAM20A | TPP2 | 0.618025 | 3 | 0 | 3 |
| FAM20A | SHISA5 | 0.613935 | 4 | 0 | 3 |
| FAM20A | UFM1 | 0.608463 | 3 | 0 | 3 |
| FAM20A | TGFB1 | 0.607482 | 3 | 0 | 3 |
| FAM20A | GPX8 | 0.593042 | 4 | 0 | 3 |
| FAM20A | LRRC15 | 0.591028 | 4 | 0 | 3 |
| FAM20A | APOE | 0.588909 | 5 | 0 | 3 |
| FAM20A | DUSP23 | 0.586407 | 3 | 0 | 3 |
| FAM20A | RBM26 | 0.584867 | 3 | 0 | 3 |
| FAM20A | SLC41A2 | 0.579151 | 5 | 0 | 4 |
| FAM20A | BASP1 | 0.577957 | 4 | 0 | 3 |
| FAM20A | ADAP2 | 0.574231 | 5 | 0 | 3 |
| FAM20A | PSMB10 | 0.567839 | 4 | 0 | 3 |
| FAM20A | CLEC11A | 0.567543 | 4 | 0 | 3 |
| FAM20A | PLA2G7 | 0.563342 | 4 | 0 | 3 |
| FAM20A | ARHGAP22-IT1 | 0.561076 | 3 | 0 | 3 |
For details and further investigation, click here
