| Full name: Nedd4 family interacting protein 1 | Alias Symbol: N4WBP5|MGC10924 | ||
| Type: protein-coding gene | Cytoband: 5q31.3 | ||
| Entrez ID: 80762 | HGNC ID: HGNC:17592 | Ensembl Gene: ENSG00000131507 | OMIM ID: 612050 |
| Drug and gene relationship at DGIdb | |||
Expression of NDFIP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NDFIP1 | 80762 | 217800_s_at | -0.0246 | 0.9600 | |
| GSE20347 | NDFIP1 | 80762 | 217800_s_at | -0.2975 | 0.1176 | |
| GSE23400 | NDFIP1 | 80762 | 217800_s_at | 0.0791 | 0.3997 | |
| GSE26886 | NDFIP1 | 80762 | 222423_at | 0.1011 | 0.6491 | |
| GSE29001 | NDFIP1 | 80762 | 217800_s_at | -0.1128 | 0.7652 | |
| GSE38129 | NDFIP1 | 80762 | 217800_s_at | -0.2436 | 0.0513 | |
| GSE45670 | NDFIP1 | 80762 | 217800_s_at | 0.0028 | 0.9869 | |
| GSE53622 | NDFIP1 | 80762 | 108453 | -0.3754 | 0.0000 | |
| GSE53624 | NDFIP1 | 80762 | 59074 | -0.1640 | 0.1067 | |
| GSE63941 | NDFIP1 | 80762 | 217800_s_at | -0.1608 | 0.6515 | |
| GSE77861 | NDFIP1 | 80762 | 217800_s_at | -0.0158 | 0.9719 | |
| GSE97050 | NDFIP1 | 80762 | A_24_P209113 | -0.0258 | 0.9263 | |
| SRP007169 | NDFIP1 | 80762 | RNAseq | -1.0039 | 0.0100 | |
| SRP008496 | NDFIP1 | 80762 | RNAseq | -0.7534 | 0.0007 | |
| SRP064894 | NDFIP1 | 80762 | RNAseq | -0.2237 | 0.0503 | |
| SRP133303 | NDFIP1 | 80762 | RNAseq | 0.0793 | 0.6558 | |
| SRP159526 | NDFIP1 | 80762 | RNAseq | 0.0574 | 0.8777 | |
| SRP193095 | NDFIP1 | 80762 | RNAseq | -0.2597 | 0.0210 | |
| SRP219564 | NDFIP1 | 80762 | RNAseq | 0.5486 | 0.2043 | |
| TCGA | NDFIP1 | 80762 | RNAseq | -0.1508 | 0.0003 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by NDFIP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NDFIP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NDFIP1 | 80762 | 1 | 12 | 17 | |
| GSE20123 | NDFIP1 | 80762 | 1 | 12 | 17 | |
| GSE43470 | NDFIP1 | 80762 | 2 | 10 | 31 | |
| GSE46452 | NDFIP1 | 80762 | 0 | 27 | 32 | |
| GSE47630 | NDFIP1 | 80762 | 0 | 20 | 20 | |
| GSE54993 | NDFIP1 | 80762 | 9 | 1 | 60 | |
| GSE54994 | NDFIP1 | 80762 | 2 | 14 | 37 | |
| GSE60625 | NDFIP1 | 80762 | 0 | 0 | 11 | |
| GSE74703 | NDFIP1 | 80762 | 2 | 7 | 27 | |
| GSE74704 | NDFIP1 | 80762 | 1 | 6 | 13 | |
| TCGA | NDFIP1 | 80762 | 3 | 38 | 55 |
Total number of gains: 21; Total number of losses: 147; Total Number of normals: 320.
Somatic mutations of NDFIP1:
Generating mutation plots.
Highly correlated genes for NDFIP1:
Showing top 20/119 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NDFIP1 | EAF1 | 0.720128 | 3 | 0 | 3 |
| NDFIP1 | JOSD2 | 0.705437 | 4 | 0 | 4 |
| NDFIP1 | ZNF567 | 0.703589 | 3 | 0 | 3 |
| NDFIP1 | DLC1 | 0.692472 | 3 | 0 | 3 |
| NDFIP1 | RAD23B | 0.680988 | 3 | 0 | 3 |
| NDFIP1 | EIF2S2 | 0.678129 | 3 | 0 | 3 |
| NDFIP1 | TMCC3 | 0.668073 | 3 | 0 | 3 |
| NDFIP1 | LACTB | 0.658497 | 3 | 0 | 3 |
| NDFIP1 | MYO1D | 0.657394 | 3 | 0 | 3 |
| NDFIP1 | STK17A | 0.655817 | 3 | 0 | 3 |
| NDFIP1 | PPP1R2 | 0.655075 | 5 | 0 | 3 |
| NDFIP1 | FAM20A | 0.649703 | 3 | 0 | 3 |
| NDFIP1 | CD44 | 0.644786 | 4 | 0 | 4 |
| NDFIP1 | CDNF | 0.63804 | 4 | 0 | 3 |
| NDFIP1 | KLHL21 | 0.632011 | 3 | 0 | 3 |
| NDFIP1 | ACAT1 | 0.628194 | 4 | 0 | 3 |
| NDFIP1 | LYST | 0.627678 | 6 | 0 | 4 |
| NDFIP1 | CAPN3 | 0.626872 | 4 | 0 | 3 |
| NDFIP1 | POLR3GL | 0.626278 | 4 | 0 | 3 |
| NDFIP1 | SLC46A3 | 0.625856 | 4 | 0 | 3 |
For details and further investigation, click here
