FCER1G

 

Full name: Fc fragment of IgE receptor Ig Alias Symbol: 
Type: protein-coding gene Cytoband: 1q23.3
Entrez ID: 2207 HGNC ID: HGNC:3611 Ensembl Gene: ENSG00000158869 OMIM ID: 147139
Drug and gene relationship at DGIdb

 

FCER1G involved pathways:

KEGG pathway Description View
hsa04071Sphingolipid signaling pathway
hsa04072Phospholipase D signaling pathway
hsa04611Platelet activation
hsa04650Natural killer cell mediated cytotoxicity
hsa04664Fc epsilon RI signaling pathway
hsa05152Tuberculosis

 

Expression of FCER1G:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 FCER1G 2207 204232_at 1.0597 0.2910
GSE20347 FCER1G 2207 204232_at 0.8843 0.0005
GSE23400 FCER1G 2207 204232_at 0.7437 0.0000
GSE26886 FCER1G 2207 204232_at 0.4507 0.2464
GSE29001 FCER1G 2207 204232_at 0.6123 0.0553
GSE38129 FCER1G 2207 204232_at 0.8481 0.0032
GSE45670 FCER1G 2207 204232_at 0.1043 0.8169
GSE53622 FCER1G 2207 145312 1.1002 0.0000
GSE53624 FCER1G 2207 43213 -0.0504 0.7410
GSE63941 FCER1G 2207 204232_at -0.0502 0.7477
GSE77861 FCER1G 2207 204232_at 0.7756 0.0103
GSE97050 FCER1G 2207 A_23_P160849 0.7661 0.1219
SRP007169 FCER1G 2207 RNAseq 3.1785 0.0000
SRP008496 FCER1G 2207 RNAseq 2.4788 0.0000
SRP064894 FCER1G 2207 RNAseq 1.3210 0.0000
SRP133303 FCER1G 2207 RNAseq 1.2734 0.0000
SRP159526 FCER1G 2207 RNAseq 1.1059 0.0940
SRP193095 FCER1G 2207 RNAseq 1.5987 0.0000
SRP219564 FCER1G 2207 RNAseq 1.9546 0.0040
TCGA FCER1G 2207 RNAseq 0.6061 0.0000

Upregulated datasets: 7; Downregulated datasets: 0.  

 

Survival by FCER1G expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of FCER1G:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 FCER1G 2207 10 0 20
GSE20123 FCER1G 2207 10 0 20
GSE43470 FCER1G 2207 7 2 34
GSE46452 FCER1G 2207 2 1 56
GSE47630 FCER1G 2207 14 0 26
GSE54993 FCER1G 2207 0 6 64
GSE54994 FCER1G 2207 16 0 37
GSE60625 FCER1G 2207 0 0 11
GSE74703 FCER1G 2207 7 2 27
GSE74704 FCER1G 2207 4 0 16
TCGA FCER1G 2207 45 3 48

Total number of gains: 115; Total number of losses: 14; Total Number of normals: 359.  

 

Somatic mutations of FCER1G:

 

Generating mutation plots.

 

Highly correlated genes for FCER1G:

 

Showing top 20/964 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
FCER1GTYROBP0.89295911011
FCER1GC1QB0.88397111011
FCER1GC1QC0.833155707
FCER1GCD1630.82410111011
FCER1GC3AR10.81755410010
FCER1GITGB20.80562110010
FCER1GFCGR2A0.79440211011
FCER1GPLA2G70.7758511011
FCER1GTFEC0.7731911009
FCER1GSLC7A70.76759211010
FCER1GSRGN0.76313511011
FCER1GZNF4690.761128303
FCER1GIGSF60.7475861009
FCER1GWDR810.744159303
FCER1GC5AR10.7395521109
FCER1GCCR10.73921911010
FCER1GRASSF40.730171505
FCER1GSERPINA10.729743907
FCER1GAIF10.72168611010
FCER1GDRAM10.72136211011

For details and further investigation, click here