| Full name: phospholipase A2 group VII | Alias Symbol: PAFAH|LDL-PLA2 | ||
| Type: protein-coding gene | Cytoband: 6p12.3 | ||
| Entrez ID: 7941 | HGNC ID: HGNC:9040 | Ensembl Gene: ENSG00000146070 | OMIM ID: 601690 |
| Drug and gene relationship at DGIdb | |||
Expression of PLA2G7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PLA2G7 | 7941 | 206214_at | 1.7136 | 0.0925 | |
| GSE20347 | PLA2G7 | 7941 | 206214_at | 1.1548 | 0.0000 | |
| GSE23400 | PLA2G7 | 7941 | 206214_at | 0.5402 | 0.0000 | |
| GSE26886 | PLA2G7 | 7941 | 206214_at | 1.1258 | 0.0012 | |
| GSE29001 | PLA2G7 | 7941 | 206214_at | 1.6604 | 0.0010 | |
| GSE38129 | PLA2G7 | 7941 | 206214_at | 1.6793 | 0.0000 | |
| GSE45670 | PLA2G7 | 7941 | 206214_at | 1.5941 | 0.0010 | |
| GSE53622 | PLA2G7 | 7941 | 92968 | 3.0200 | 0.0000 | |
| GSE53624 | PLA2G7 | 7941 | 92968 | 3.1804 | 0.0000 | |
| GSE63941 | PLA2G7 | 7941 | 206214_at | 0.3678 | 0.6589 | |
| GSE77861 | PLA2G7 | 7941 | 206214_at | 0.3332 | 0.0113 | |
| GSE97050 | PLA2G7 | 7941 | A_23_P145096 | 1.6455 | 0.1072 | |
| SRP007169 | PLA2G7 | 7941 | RNAseq | 5.7165 | 0.0000 | |
| SRP008496 | PLA2G7 | 7941 | RNAseq | 3.8804 | 0.0000 | |
| SRP064894 | PLA2G7 | 7941 | RNAseq | 3.3075 | 0.0000 | |
| SRP133303 | PLA2G7 | 7941 | RNAseq | 2.8359 | 0.0000 | |
| SRP159526 | PLA2G7 | 7941 | RNAseq | 2.5661 | 0.0008 | |
| SRP193095 | PLA2G7 | 7941 | RNAseq | 2.1512 | 0.0000 | |
| SRP219564 | PLA2G7 | 7941 | RNAseq | 4.1678 | 0.0000 | |
| TCGA | PLA2G7 | 7941 | RNAseq | 1.6561 | 0.0000 |
Upregulated datasets: 15; Downregulated datasets: 0.
Survival by PLA2G7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PLA2G7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PLA2G7 | 7941 | 6 | 2 | 22 | |
| GSE20123 | PLA2G7 | 7941 | 6 | 2 | 22 | |
| GSE43470 | PLA2G7 | 7941 | 5 | 0 | 38 | |
| GSE46452 | PLA2G7 | 7941 | 2 | 10 | 47 | |
| GSE47630 | PLA2G7 | 7941 | 7 | 5 | 28 | |
| GSE54993 | PLA2G7 | 7941 | 3 | 1 | 66 | |
| GSE54994 | PLA2G7 | 7941 | 8 | 3 | 42 | |
| GSE60625 | PLA2G7 | 7941 | 0 | 3 | 8 | |
| GSE74703 | PLA2G7 | 7941 | 5 | 0 | 31 | |
| GSE74704 | PLA2G7 | 7941 | 2 | 1 | 17 | |
| TCGA | PLA2G7 | 7941 | 18 | 14 | 64 |
Total number of gains: 62; Total number of losses: 41; Total Number of normals: 385.
Somatic mutations of PLA2G7:
Generating mutation plots.
Highly correlated genes for PLA2G7:
Showing top 20/1849 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PLA2G7 | FCGR3A | 0.801785 | 3 | 0 | 3 |
| PLA2G7 | TFEC | 0.798152 | 10 | 0 | 10 |
| PLA2G7 | FCER1G | 0.77585 | 11 | 0 | 11 |
| PLA2G7 | MMP12 | 0.774365 | 12 | 0 | 11 |
| PLA2G7 | SLC7A7 | 0.767662 | 12 | 0 | 12 |
| PLA2G7 | SNX10 | 0.76374 | 12 | 0 | 11 |
| PLA2G7 | FAM89A | 0.756242 | 3 | 0 | 3 |
| PLA2G7 | USP41 | 0.755372 | 3 | 0 | 3 |
| PLA2G7 | APOC1 | 0.754227 | 12 | 0 | 11 |
| PLA2G7 | CAPN12 | 0.750503 | 4 | 0 | 4 |
| PLA2G7 | PDIA5 | 0.746975 | 3 | 0 | 3 |
| PLA2G7 | ZAP70 | 0.742941 | 3 | 0 | 3 |
| PLA2G7 | APOE | 0.74168 | 12 | 0 | 12 |
| PLA2G7 | IGSF6 | 0.740475 | 11 | 0 | 10 |
| PLA2G7 | TTYH3 | 0.739915 | 7 | 0 | 7 |
| PLA2G7 | ARPC1B | 0.738309 | 11 | 0 | 11 |
| PLA2G7 | PARP12 | 0.73791 | 11 | 0 | 11 |
| PLA2G7 | DDX60L | 0.735685 | 5 | 0 | 5 |
| PLA2G7 | C1QB | 0.731071 | 12 | 0 | 12 |
| PLA2G7 | IL4I1 | 0.729014 | 8 | 0 | 7 |
For details and further investigation, click here
