PAX9

 

Full name: paired box 9 Alias Symbol: 
Type: protein-coding gene Cytoband: 14q13.3
Entrez ID: 5083 HGNC ID: HGNC:8623 Ensembl Gene: ENSG00000198807 OMIM ID: 167416
Drug and gene relationship at DGIdb

 

Expression of PAX9:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PAX9 5083 231145_at -2.5183 0.2310
GSE20347 PAX9 5083 207059_at -1.7127 0.0000
GSE23400 PAX9 5083 207059_at -1.8667 0.0000
GSE26886 PAX9 5083 231145_at -4.2550 0.0000
GSE29001 PAX9 5083 207059_at -0.9367 0.0002
GSE38129 PAX9 5083 207059_at -1.2500 0.0002
GSE45670 PAX9 5083 231145_at -1.2326 0.0167
GSE53622 PAX9 5083 420 -2.2979 0.0000
GSE53624 PAX9 5083 12615 -2.9790 0.0000
GSE63941 PAX9 5083 207059_at 2.6953 0.0215
GSE77861 PAX9 5083 207059_at -0.9164 0.0545
GSE97050 PAX9 5083 A_23_P426944 -0.0033 0.9975
SRP007169 PAX9 5083 RNAseq -3.2972 0.0000
SRP008496 PAX9 5083 RNAseq -3.6956 0.0000
SRP064894 PAX9 5083 RNAseq -3.3658 0.0000
SRP133303 PAX9 5083 RNAseq -1.0398 0.0700
SRP159526 PAX9 5083 RNAseq -3.2379 0.0000
SRP219564 PAX9 5083 RNAseq -2.9619 0.0072
TCGA PAX9 5083 RNAseq 0.9253 0.0004

Upregulated datasets: 1; Downregulated datasets: 12.  


 

Survival by PAX9 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of PAX9:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PAX9 5083 11 4 15
GSE20123 PAX9 5083 12 4 14
GSE43470 PAX9 5083 8 2 33
GSE46452 PAX9 5083 18 2 39
GSE47630 PAX9 5083 11 10 19
GSE54993 PAX9 5083 3 11 56
GSE54994 PAX9 5083 19 5 29
GSE60625 PAX9 5083 0 2 9
GSE74703 PAX9 5083 7 2 27
GSE74704 PAX9 5083 6 3 11
TCGA PAX9 5083 35 14 47

Total number of gains: 130; Total number of losses: 59; Total Number of normals: 299.  


 

Somatic mutations of PAX9:

 

Generating mutation plots.

 

Highly correlated genes for PAX9:

 

Showing top 20/1161 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PAX9NCCRP10.875094303
PAX9PCBP1-AS10.82229303
PAX9CEACAM50.81681913013
PAX9IL36A0.8096511011
PAX9C18orf250.80950810010
PAX9EPS8L20.80778511011
PAX9RNF1410.80596410010
PAX9UPK3B0.80582303
PAX9IL1RN0.8045712012
PAX9FUT30.80214112012
PAX9CYSRT10.800911606
PAX9EVPL0.80031512011
PAX9SMIM50.799987606
PAX9OTOP30.798758303
PAX9CEACAM60.79701513012
PAX9PPL0.79661812012
PAX9GDPD30.79542411011
PAX9MALL0.79459411011
PAX9BLNK0.79060910010
PAX9ACPP0.79033412011

For details and further investigation, click here