| Full name: FERM, ARH/RhoGEF and pleckstrin domain protein 2 | Alias Symbol: KIAA0793|FIR|PLEKHC3|FRG | ||
| Type: protein-coding gene | Cytoband: 2q37.3 | ||
| Entrez ID: 9855 | HGNC ID: HGNC:16460 | Ensembl Gene: ENSG00000006607 | OMIM ID: 617586 |
| Drug and gene relationship at DGIdb | |||
FARP2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04015 | Rap1 signaling pathway | |
| hsa04520 | Adherens junction |
Expression of FARP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FARP2 | 9855 | 225652_at | 0.1661 | 0.7796 | |
| GSE20347 | FARP2 | 9855 | 204511_at | -0.3004 | 0.0164 | |
| GSE23400 | FARP2 | 9855 | 204511_at | -0.1890 | 0.0000 | |
| GSE26886 | FARP2 | 9855 | 225652_at | -0.2004 | 0.2845 | |
| GSE29001 | FARP2 | 9855 | 204511_at | -0.3882 | 0.0978 | |
| GSE38129 | FARP2 | 9855 | 204511_at | -0.3240 | 0.0009 | |
| GSE45670 | FARP2 | 9855 | 225652_at | 0.4851 | 0.0002 | |
| GSE53622 | FARP2 | 9855 | 20358 | -0.6774 | 0.0000 | |
| GSE53624 | FARP2 | 9855 | 20358 | -0.6966 | 0.0000 | |
| GSE63941 | FARP2 | 9855 | 225652_at | -0.3009 | 0.5402 | |
| GSE77861 | FARP2 | 9855 | 225652_at | 0.4643 | 0.0057 | |
| GSE97050 | FARP2 | 9855 | A_33_P3350728 | -0.1465 | 0.4438 | |
| SRP007169 | FARP2 | 9855 | RNAseq | -0.3003 | 0.3580 | |
| SRP008496 | FARP2 | 9855 | RNAseq | -0.2361 | 0.3405 | |
| SRP064894 | FARP2 | 9855 | RNAseq | -0.6915 | 0.0046 | |
| SRP133303 | FARP2 | 9855 | RNAseq | -0.0456 | 0.7135 | |
| SRP159526 | FARP2 | 9855 | RNAseq | -0.3791 | 0.1993 | |
| SRP193095 | FARP2 | 9855 | RNAseq | -0.2861 | 0.0860 | |
| SRP219564 | FARP2 | 9855 | RNAseq | -0.5141 | 0.2014 | |
| TCGA | FARP2 | 9855 | RNAseq | -0.3139 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FARP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FARP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FARP2 | 9855 | 1 | 12 | 17 | |
| GSE20123 | FARP2 | 9855 | 1 | 12 | 17 | |
| GSE43470 | FARP2 | 9855 | 1 | 9 | 33 | |
| GSE46452 | FARP2 | 9855 | 0 | 5 | 54 | |
| GSE47630 | FARP2 | 9855 | 4 | 5 | 31 | |
| GSE54993 | FARP2 | 9855 | 4 | 3 | 63 | |
| GSE54994 | FARP2 | 9855 | 8 | 9 | 36 | |
| GSE60625 | FARP2 | 9855 | 0 | 3 | 8 | |
| GSE74703 | FARP2 | 9855 | 1 | 7 | 28 | |
| GSE74704 | FARP2 | 9855 | 1 | 5 | 14 | |
| TCGA | FARP2 | 9855 | 12 | 29 | 55 |
Total number of gains: 33; Total number of losses: 99; Total Number of normals: 356.
Somatic mutations of FARP2:
Generating mutation plots.
Highly correlated genes for FARP2:
Showing top 20/51 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FARP2 | FBRSL1 | 0.739364 | 3 | 0 | 3 |
| FARP2 | HOXC9 | 0.658654 | 3 | 0 | 3 |
| FARP2 | MAGEA8 | 0.654759 | 3 | 0 | 3 |
| FARP2 | FAM163B | 0.65323 | 3 | 0 | 3 |
| FARP2 | GCH1 | 0.648192 | 3 | 0 | 3 |
| FARP2 | SDCBP2 | 0.63982 | 3 | 0 | 3 |
| FARP2 | CORO2A | 0.631669 | 3 | 0 | 3 |
| FARP2 | MUC22 | 0.630969 | 3 | 0 | 3 |
| FARP2 | DMC1 | 0.629927 | 3 | 0 | 3 |
| FARP2 | STK25 | 0.628473 | 4 | 0 | 3 |
| FARP2 | MTFP1 | 0.624299 | 3 | 0 | 3 |
| FARP2 | PTCRA | 0.613709 | 4 | 0 | 4 |
| FARP2 | EIF1AD | 0.610865 | 4 | 0 | 3 |
| FARP2 | ACR | 0.607564 | 5 | 0 | 4 |
| FARP2 | UPK3A | 0.597637 | 4 | 0 | 3 |
| FARP2 | EVX1 | 0.590771 | 5 | 0 | 4 |
| FARP2 | ZNF264 | 0.588764 | 7 | 0 | 6 |
| FARP2 | LRIT1 | 0.586443 | 4 | 0 | 3 |
| FARP2 | HES5 | 0.584271 | 5 | 0 | 4 |
| FARP2 | GRIN1 | 0.574068 | 5 | 0 | 4 |
For details and further investigation, click here
