CORO2A

 

Full name: coronin 2A Alias Symbol: IR10|WDR2
Type: protein-coding gene Cytoband: 9q22.33
Entrez ID: 7464 HGNC ID: HGNC:2255 Ensembl Gene: ENSG00000106789 OMIM ID: 602159
Drug and gene relationship at DGIdb

 

Expression of CORO2A:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CORO2A 7464 227177_at 0.2449 0.8149
GSE20347 CORO2A 7464 205538_at -0.0432 0.8607
GSE23400 CORO2A 7464 205538_at 0.1536 0.0679
GSE26886 CORO2A 7464 227177_at -0.0305 0.9200
GSE29001 CORO2A 7464 205538_at 0.2314 0.3354
GSE38129 CORO2A 7464 205538_at 0.3345 0.1501
GSE45670 CORO2A 7464 227177_at 0.3614 0.0756
GSE53622 CORO2A 7464 48602 -0.0958 0.6545
GSE53624 CORO2A 7464 48602 -0.0748 0.6058
GSE63941 CORO2A 7464 227177_at 3.9071 0.0000
GSE77861 CORO2A 7464 227177_at 0.2163 0.6087
GSE97050 CORO2A 7464 A_23_P135061 0.5279 0.2017
SRP007169 CORO2A 7464 RNAseq 0.6837 0.1239
SRP008496 CORO2A 7464 RNAseq 0.3387 0.2841
SRP064894 CORO2A 7464 RNAseq 0.0561 0.8350
SRP133303 CORO2A 7464 RNAseq 0.1147 0.6720
SRP159526 CORO2A 7464 RNAseq -0.0338 0.9451
SRP193095 CORO2A 7464 RNAseq -0.3241 0.0937
SRP219564 CORO2A 7464 RNAseq -0.1886 0.8066
TCGA CORO2A 7464 RNAseq 0.2083 0.0215

Upregulated datasets: 1; Downregulated datasets: 0.  


 

Survival by CORO2A expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of CORO2A:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CORO2A 7464 4 9 17
GSE20123 CORO2A 7464 5 8 17
GSE43470 CORO2A 7464 6 3 34
GSE46452 CORO2A 7464 6 14 39
GSE47630 CORO2A 7464 1 17 22
GSE54993 CORO2A 7464 3 3 64
GSE54994 CORO2A 7464 8 11 34
GSE60625 CORO2A 7464 0 0 11
GSE74703 CORO2A 7464 5 3 28
GSE74704 CORO2A 7464 3 5 12
TCGA CORO2A 7464 27 22 47

Total number of gains: 68; Total number of losses: 95; Total Number of normals: 325.  


 

Somatic mutations of CORO2A:

 

Generating mutation plots.

 

Highly correlated genes for CORO2A:

 

Showing top 20/217 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CORO2ADNAJC140.704509303
CORO2ASLC25A390.697659303
CORO2ASYTL10.694198303
CORO2AMAL20.691107404
CORO2ACBX80.690838403
CORO2AACTR3B0.68565303
CORO2ATOR2A0.664864303
CORO2AASF1B0.654876504
CORO2ASFN0.653836303
CORO2AMREG0.647363404
CORO2ATRIM290.64716505
CORO2ARNF440.63994403
CORO2ARARG0.638392403
CORO2AACAT20.632911403
CORO2AAP1S30.632604303
CORO2AFARP20.631669303
CORO2AZWINT0.631401504
CORO2AKIAA15220.62947605
CORO2AMAP3K90.625066504
CORO2AEBP0.624334603

For details and further investigation, click here