| Full name: rearranged L-myc fusion | Alias Symbol: ZNF292L|Zn-15L | ||
| Type: protein-coding gene | Cytoband: 1p34.2 | ||
| Entrez ID: 6018 | HGNC ID: HGNC:10025 | Ensembl Gene: ENSG00000117000 | OMIM ID: 180610 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RLF:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RLF | 6018 | 204243_at | -0.2436 | 0.6143 | |
| GSE20347 | RLF | 6018 | 204243_at | 0.0877 | 0.6203 | |
| GSE23400 | RLF | 6018 | 204243_at | 0.1811 | 0.0536 | |
| GSE26886 | RLF | 6018 | 204243_at | 0.0446 | 0.8749 | |
| GSE29001 | RLF | 6018 | 204243_at | 0.1588 | 0.5238 | |
| GSE38129 | RLF | 6018 | 204243_at | 0.0617 | 0.6619 | |
| GSE45670 | RLF | 6018 | 204243_at | 0.1197 | 0.4571 | |
| GSE53622 | RLF | 6018 | 41699 | -0.0285 | 0.7990 | |
| GSE53624 | RLF | 6018 | 41699 | 0.1006 | 0.2029 | |
| GSE63941 | RLF | 6018 | 204243_at | 0.4348 | 0.3564 | |
| GSE77861 | RLF | 6018 | 204243_at | 0.2705 | 0.4275 | |
| GSE97050 | RLF | 6018 | A_23_P126037 | -0.2459 | 0.3225 | |
| SRP007169 | RLF | 6018 | RNAseq | 0.8249 | 0.0931 | |
| SRP008496 | RLF | 6018 | RNAseq | 0.6883 | 0.0336 | |
| SRP064894 | RLF | 6018 | RNAseq | -0.3980 | 0.2039 | |
| SRP133303 | RLF | 6018 | RNAseq | 0.1648 | 0.3620 | |
| SRP193095 | RLF | 6018 | RNAseq | -0.0647 | 0.6276 | |
| SRP219564 | RLF | 6018 | RNAseq | -0.2530 | 0.5832 | |
| TCGA | RLF | 6018 | RNAseq | 0.0479 | 0.5002 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RLF expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RLF:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RLF | 6018 | 3 | 4 | 23 | |
| GSE20123 | RLF | 6018 | 2 | 3 | 25 | |
| GSE43470 | RLF | 6018 | 7 | 2 | 34 | |
| GSE46452 | RLF | 6018 | 4 | 1 | 54 | |
| GSE47630 | RLF | 6018 | 9 | 2 | 29 | |
| GSE54993 | RLF | 6018 | 0 | 1 | 69 | |
| GSE54994 | RLF | 6018 | 13 | 2 | 38 | |
| GSE60625 | RLF | 6018 | 0 | 0 | 11 | |
| GSE74703 | RLF | 6018 | 6 | 1 | 29 | |
| GSE74704 | RLF | 6018 | 1 | 0 | 19 | |
| TCGA | RLF | 6018 | 16 | 16 | 64 |
Total number of gains: 61; Total number of losses: 32; Total Number of normals: 395.
Somatic mutations of RLF:
Generating mutation plots.
Highly correlated genes for RLF:
Showing top 20/174 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RLF | CNOT2 | 0.764735 | 3 | 0 | 3 |
| RLF | XRCC5 | 0.738889 | 3 | 0 | 3 |
| RLF | ZRANB1 | 0.732219 | 3 | 0 | 3 |
| RLF | TMEM107 | 0.731867 | 3 | 0 | 3 |
| RLF | CLPX | 0.706506 | 3 | 0 | 3 |
| RLF | NFAT5 | 0.705552 | 3 | 0 | 3 |
| RLF | COMMD1 | 0.705385 | 3 | 0 | 3 |
| RLF | SOCS2 | 0.70447 | 3 | 0 | 3 |
| RLF | ALDOA | 0.702775 | 3 | 0 | 3 |
| RLF | MRPS18A | 0.699587 | 3 | 0 | 3 |
| RLF | SNAPC3 | 0.69424 | 3 | 0 | 3 |
| RLF | FUBP3 | 0.683215 | 3 | 0 | 3 |
| RLF | RNFT1 | 0.681558 | 3 | 0 | 3 |
| RLF | ZMYM2 | 0.68145 | 3 | 0 | 3 |
| RLF | SEC11A | 0.680892 | 3 | 0 | 3 |
| RLF | ZC3H14 | 0.679098 | 3 | 0 | 3 |
| RLF | GAPVD1 | 0.677675 | 3 | 0 | 3 |
| RLF | DDX19A | 0.669683 | 4 | 0 | 3 |
| RLF | ATXN2 | 0.668724 | 3 | 0 | 3 |
| RLF | ESYT2 | 0.667933 | 4 | 0 | 3 |
For details and further investigation, click here
