| Full name: eukaryotic translation initiation factor 4A3 | Alias Symbol: KIAA0111|EIF4AIII|Fal1 | ||
| Type: protein-coding gene | Cytoband: 17q25.3 | ||
| Entrez ID: 9775 | HGNC ID: HGNC:18683 | Ensembl Gene: ENSG00000141543 | OMIM ID: 608546 |
| Drug and gene relationship at DGIdb | |||
Expression of EIF4A3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EIF4A3 | 9775 | 201303_at | 0.4030 | 0.3211 | |
| GSE20347 | EIF4A3 | 9775 | 201303_at | 0.2345 | 0.1049 | |
| GSE23400 | EIF4A3 | 9775 | 201303_at | 0.3356 | 0.0000 | |
| GSE26886 | EIF4A3 | 9775 | 201303_at | -0.3582 | 0.0321 | |
| GSE29001 | EIF4A3 | 9775 | 201303_at | 0.1894 | 0.5169 | |
| GSE38129 | EIF4A3 | 9775 | 201303_at | 0.4487 | 0.0009 | |
| GSE45670 | EIF4A3 | 9775 | 201303_at | 0.4214 | 0.0085 | |
| GSE53622 | EIF4A3 | 9775 | 53322 | 0.3191 | 0.0000 | |
| GSE53624 | EIF4A3 | 9775 | 53322 | 0.3220 | 0.0000 | |
| GSE63941 | EIF4A3 | 9775 | 201303_at | 0.8026 | 0.0114 | |
| GSE77861 | EIF4A3 | 9775 | 201303_at | 0.1819 | 0.4945 | |
| GSE97050 | EIF4A3 | 9775 | A_23_P141636 | 0.2582 | 0.3646 | |
| SRP007169 | EIF4A3 | 9775 | RNAseq | -0.3453 | 0.3815 | |
| SRP008496 | EIF4A3 | 9775 | RNAseq | -0.4580 | 0.0468 | |
| SRP064894 | EIF4A3 | 9775 | RNAseq | 0.2980 | 0.1451 | |
| SRP133303 | EIF4A3 | 9775 | RNAseq | 0.3095 | 0.0141 | |
| SRP159526 | EIF4A3 | 9775 | RNAseq | 0.2291 | 0.4346 | |
| SRP193095 | EIF4A3 | 9775 | RNAseq | 0.2286 | 0.2089 | |
| SRP219564 | EIF4A3 | 9775 | RNAseq | 0.0214 | 0.9448 | |
| TCGA | EIF4A3 | 9775 | RNAseq | 0.2897 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by EIF4A3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EIF4A3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EIF4A3 | 9775 | 4 | 3 | 23 | |
| GSE20123 | EIF4A3 | 9775 | 4 | 3 | 23 | |
| GSE43470 | EIF4A3 | 9775 | 2 | 6 | 35 | |
| GSE46452 | EIF4A3 | 9775 | 34 | 0 | 25 | |
| GSE47630 | EIF4A3 | 9775 | 9 | 1 | 30 | |
| GSE54993 | EIF4A3 | 9775 | 2 | 5 | 63 | |
| GSE54994 | EIF4A3 | 9775 | 10 | 6 | 37 | |
| GSE60625 | EIF4A3 | 9775 | 6 | 0 | 5 | |
| GSE74703 | EIF4A3 | 9775 | 2 | 4 | 30 | |
| GSE74704 | EIF4A3 | 9775 | 4 | 3 | 13 | |
| TCGA | EIF4A3 | 9775 | 29 | 9 | 58 |
Total number of gains: 106; Total number of losses: 40; Total Number of normals: 342.
Somatic mutations of EIF4A3:
Generating mutation plots.
Highly correlated genes for EIF4A3:
Showing top 20/827 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EIF4A3 | CIB1 | 0.765081 | 4 | 0 | 4 |
| EIF4A3 | CTDSPL2 | 0.758068 | 3 | 0 | 3 |
| EIF4A3 | IRF2BPL | 0.746656 | 3 | 0 | 3 |
| EIF4A3 | MRPL38 | 0.731003 | 5 | 0 | 5 |
| EIF4A3 | C12orf45 | 0.722047 | 4 | 0 | 4 |
| EIF4A3 | MCU | 0.720643 | 3 | 0 | 3 |
| EIF4A3 | FBXO16 | 0.713309 | 3 | 0 | 3 |
| EIF4A3 | INTS9 | 0.710687 | 4 | 0 | 3 |
| EIF4A3 | LRRC59 | 0.707447 | 8 | 0 | 6 |
| EIF4A3 | MKNK1 | 0.706606 | 4 | 0 | 4 |
| EIF4A3 | CDYL | 0.700258 | 4 | 0 | 3 |
| EIF4A3 | UNK | 0.699757 | 3 | 0 | 3 |
| EIF4A3 | PACS1 | 0.699318 | 3 | 0 | 3 |
| EIF4A3 | RIMKLA | 0.697343 | 3 | 0 | 3 |
| EIF4A3 | MOB3C | 0.695746 | 3 | 0 | 3 |
| EIF4A3 | UQCR10 | 0.693409 | 4 | 0 | 3 |
| EIF4A3 | HIGD2A | 0.692124 | 3 | 0 | 3 |
| EIF4A3 | MBOAT1 | 0.691431 | 3 | 0 | 3 |
| EIF4A3 | TACO1 | 0.6862 | 9 | 0 | 9 |
| EIF4A3 | EME1 | 0.685378 | 4 | 0 | 4 |
For details and further investigation, click here
