| Full name: FYVE, RhoGEF and PH domain containing 1 | Alias Symbol: ZFYVE3 | ||
| Type: protein-coding gene | Cytoband: Xp11.22 | ||
| Entrez ID: 2245 | HGNC ID: HGNC:3663 | Ensembl Gene: ENSG00000102302 | OMIM ID: 300546 |
| Drug and gene relationship at DGIdb | |||
FGD1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04810 | Regulation of actin cytoskeleton |
Expression of FGD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FGD1 | 2245 | 204819_at | 0.3936 | 0.5653 | |
| GSE20347 | FGD1 | 2245 | 204819_at | -0.1036 | 0.4744 | |
| GSE23400 | FGD1 | 2245 | 204819_at | -0.0953 | 0.0631 | |
| GSE26886 | FGD1 | 2245 | 204819_at | -0.3276 | 0.0414 | |
| GSE29001 | FGD1 | 2245 | 204819_at | -0.1966 | 0.4016 | |
| GSE38129 | FGD1 | 2245 | 204819_at | 0.0569 | 0.6979 | |
| GSE45670 | FGD1 | 2245 | 204819_at | 0.0001 | 0.9998 | |
| GSE53622 | FGD1 | 2245 | 38190 | -0.1138 | 0.1920 | |
| GSE53624 | FGD1 | 2245 | 38190 | -0.0233 | 0.7831 | |
| GSE63941 | FGD1 | 2245 | 204819_at | -0.3284 | 0.6416 | |
| GSE77861 | FGD1 | 2245 | 204819_at | -0.0523 | 0.7964 | |
| GSE97050 | FGD1 | 2245 | A_24_P143138 | -0.6361 | 0.0908 | |
| SRP007169 | FGD1 | 2245 | RNAseq | -0.3263 | 0.4725 | |
| SRP064894 | FGD1 | 2245 | RNAseq | 0.4441 | 0.1574 | |
| SRP133303 | FGD1 | 2245 | RNAseq | -0.0271 | 0.9271 | |
| SRP159526 | FGD1 | 2245 | RNAseq | 1.0396 | 0.0002 | |
| SRP193095 | FGD1 | 2245 | RNAseq | 0.5061 | 0.0448 | |
| SRP219564 | FGD1 | 2245 | RNAseq | 0.6516 | 0.2099 | |
| TCGA | FGD1 | 2245 | RNAseq | 0.1978 | 0.0184 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by FGD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FGD1:
No record found for this gene.
Somatic mutations of FGD1:
Generating mutation plots.
Highly correlated genes for FGD1:
Showing top 20/48 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FGD1 | PAQR6 | 0.63049 | 3 | 0 | 3 |
| FGD1 | OR52A1 | 0.628654 | 3 | 0 | 3 |
| FGD1 | SRCAP | 0.622241 | 5 | 0 | 4 |
| FGD1 | SLC17A4 | 0.619183 | 3 | 0 | 3 |
| FGD1 | ACBD4 | 0.617062 | 3 | 0 | 3 |
| FGD1 | MPZ | 0.616964 | 4 | 0 | 3 |
| FGD1 | DPP6 | 0.611518 | 4 | 0 | 4 |
| FGD1 | NR1I3 | 0.596379 | 4 | 0 | 3 |
| FGD1 | PPP1R3A | 0.591816 | 3 | 0 | 3 |
| FGD1 | HSD3B1 | 0.586795 | 4 | 0 | 3 |
| FGD1 | FASTK | 0.580774 | 5 | 0 | 4 |
| FGD1 | KCNJ3 | 0.580288 | 3 | 0 | 3 |
| FGD1 | IGFBPL1 | 0.571714 | 4 | 0 | 3 |
| FGD1 | GRIK5 | 0.5703 | 4 | 0 | 3 |
| FGD1 | NYNRIN | 0.570227 | 3 | 0 | 3 |
| FGD1 | KIF5A | 0.56726 | 4 | 0 | 3 |
| FGD1 | ZNF576 | 0.566669 | 5 | 0 | 5 |
| FGD1 | GRIN2A | 0.566588 | 3 | 0 | 3 |
| FGD1 | FA2H | 0.564787 | 3 | 0 | 3 |
| FGD1 | MYH14 | 0.564268 | 3 | 0 | 3 |
For details and further investigation, click here
