| Full name: fat storage inducing transmembrane protein 2 | Alias Symbol: dJ881L22.2|FIT2 | ||
| Type: protein-coding gene | Cytoband: 20q13.12 | ||
| Entrez ID: 128486 | HGNC ID: HGNC:16135 | Ensembl Gene: ENSG00000197296 | OMIM ID: 612029 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of FITM2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FITM2 | 128486 | 226805_at | 0.3817 | 0.5444 | |
| GSE26886 | FITM2 | 128486 | 226805_at | -0.4146 | 0.0469 | |
| GSE45670 | FITM2 | 128486 | 226805_at | 0.0538 | 0.8426 | |
| GSE53622 | FITM2 | 128486 | 33045 | 0.1222 | 0.2995 | |
| GSE53624 | FITM2 | 128486 | 33045 | 0.5675 | 0.0000 | |
| GSE63941 | FITM2 | 128486 | 226805_at | -0.5582 | 0.4962 | |
| GSE77861 | FITM2 | 128486 | 233061_at | -0.1040 | 0.4512 | |
| GSE97050 | FITM2 | 128486 | A_24_P203407 | 0.1545 | 0.6706 | |
| SRP007169 | FITM2 | 128486 | RNAseq | 0.5988 | 0.2794 | |
| SRP008496 | FITM2 | 128486 | RNAseq | 0.6886 | 0.0791 | |
| SRP064894 | FITM2 | 128486 | RNAseq | 0.1729 | 0.2515 | |
| SRP133303 | FITM2 | 128486 | RNAseq | 0.1085 | 0.4863 | |
| SRP159526 | FITM2 | 128486 | RNAseq | 0.1570 | 0.5695 | |
| SRP193095 | FITM2 | 128486 | RNAseq | 0.1375 | 0.1954 | |
| SRP219564 | FITM2 | 128486 | RNAseq | -0.2373 | 0.5465 | |
| TCGA | FITM2 | 128486 | RNAseq | -0.3094 | 0.0039 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FITM2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FITM2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FITM2 | 128486 | 13 | 1 | 16 | |
| GSE20123 | FITM2 | 128486 | 13 | 1 | 16 | |
| GSE43470 | FITM2 | 128486 | 12 | 1 | 30 | |
| GSE46452 | FITM2 | 128486 | 29 | 0 | 30 | |
| GSE47630 | FITM2 | 128486 | 25 | 0 | 15 | |
| GSE54993 | FITM2 | 128486 | 0 | 17 | 53 | |
| GSE54994 | FITM2 | 128486 | 25 | 0 | 28 | |
| GSE60625 | FITM2 | 128486 | 0 | 0 | 11 | |
| GSE74703 | FITM2 | 128486 | 10 | 1 | 25 | |
| GSE74704 | FITM2 | 128486 | 9 | 0 | 11 | |
| TCGA | FITM2 | 128486 | 45 | 3 | 48 |
Total number of gains: 181; Total number of losses: 24; Total Number of normals: 283.
Somatic mutations of FITM2:
Generating mutation plots.
Highly correlated genes for FITM2:
Showing top 20/207 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FITM2 | NECAP2 | 0.74982 | 3 | 0 | 3 |
| FITM2 | RBM22 | 0.730145 | 3 | 0 | 3 |
| FITM2 | UFSP2 | 0.721487 | 3 | 0 | 3 |
| FITM2 | C7orf50 | 0.719798 | 4 | 0 | 3 |
| FITM2 | PIGK | 0.712428 | 4 | 0 | 3 |
| FITM2 | TERF2IP | 0.712197 | 3 | 0 | 3 |
| FITM2 | FYTTD1 | 0.705899 | 4 | 0 | 3 |
| FITM2 | DHRS3 | 0.70509 | 3 | 0 | 3 |
| FITM2 | ERCC6 | 0.704562 | 3 | 0 | 3 |
| FITM2 | TYW3 | 0.703655 | 3 | 0 | 3 |
| FITM2 | COMMD3 | 0.697965 | 3 | 0 | 3 |
| FITM2 | ADAT1 | 0.696869 | 3 | 0 | 3 |
| FITM2 | ZFYVE1 | 0.693499 | 3 | 0 | 3 |
| FITM2 | MTF1 | 0.692087 | 3 | 0 | 3 |
| FITM2 | METAP2 | 0.691583 | 4 | 0 | 4 |
| FITM2 | TACO1 | 0.691381 | 4 | 0 | 3 |
| FITM2 | ABHD6 | 0.68965 | 3 | 0 | 3 |
| FITM2 | PTPN1 | 0.688238 | 4 | 0 | 3 |
| FITM2 | TIMM9 | 0.686349 | 3 | 0 | 3 |
| FITM2 | DEK | 0.685957 | 3 | 0 | 3 |
For details and further investigation, click here
