| Full name: phosphatidylinositol glycan anchor biosynthesis class K | Alias Symbol: hGPI8|GPI8 | ||
| Type: protein-coding gene | Cytoband: 1p31.1 | ||
| Entrez ID: 10026 | HGNC ID: HGNC:8965 | Ensembl Gene: ENSG00000142892 | OMIM ID: 605087 |
| Drug and gene relationship at DGIdb | |||
Expression of PIGK:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PIGK | 10026 | 209707_at | 0.2299 | 0.7231 | |
| GSE20347 | PIGK | 10026 | 209707_at | 0.3210 | 0.0492 | |
| GSE23400 | PIGK | 10026 | 209707_at | 0.4148 | 0.0000 | |
| GSE26886 | PIGK | 10026 | 209707_at | 0.7663 | 0.0120 | |
| GSE29001 | PIGK | 10026 | 209707_at | 0.6753 | 0.0987 | |
| GSE38129 | PIGK | 10026 | 209707_at | 0.2264 | 0.1682 | |
| GSE45670 | PIGK | 10026 | 209707_at | 0.0974 | 0.7202 | |
| GSE53622 | PIGK | 10026 | 55457 | 0.1471 | 0.1222 | |
| GSE53624 | PIGK | 10026 | 55457 | 0.4582 | 0.0000 | |
| GSE63941 | PIGK | 10026 | 209707_at | -0.8437 | 0.0716 | |
| GSE77861 | PIGK | 10026 | 209707_at | -0.0504 | 0.8378 | |
| GSE97050 | PIGK | 10026 | A_23_P34307 | 0.0941 | 0.8100 | |
| SRP007169 | PIGK | 10026 | RNAseq | 0.5866 | 0.1393 | |
| SRP008496 | PIGK | 10026 | RNAseq | 0.5713 | 0.0259 | |
| SRP064894 | PIGK | 10026 | RNAseq | 0.4915 | 0.0054 | |
| SRP133303 | PIGK | 10026 | RNAseq | 0.6495 | 0.0000 | |
| SRP159526 | PIGK | 10026 | RNAseq | -0.0376 | 0.8544 | |
| SRP193095 | PIGK | 10026 | RNAseq | 0.0965 | 0.5080 | |
| SRP219564 | PIGK | 10026 | RNAseq | 0.5609 | 0.2305 | |
| TCGA | PIGK | 10026 | RNAseq | -0.1186 | 0.0312 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PIGK expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PIGK:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PIGK | 10026 | 0 | 7 | 23 | |
| GSE20123 | PIGK | 10026 | 0 | 7 | 23 | |
| GSE43470 | PIGK | 10026 | 3 | 4 | 36 | |
| GSE46452 | PIGK | 10026 | 0 | 1 | 58 | |
| GSE47630 | PIGK | 10026 | 8 | 6 | 26 | |
| GSE54993 | PIGK | 10026 | 0 | 0 | 70 | |
| GSE54994 | PIGK | 10026 | 6 | 3 | 44 | |
| GSE60625 | PIGK | 10026 | 0 | 0 | 11 | |
| GSE74703 | PIGK | 10026 | 2 | 3 | 31 | |
| GSE74704 | PIGK | 10026 | 0 | 4 | 16 | |
| TCGA | PIGK | 10026 | 8 | 24 | 64 |
Total number of gains: 27; Total number of losses: 59; Total Number of normals: 402.
Somatic mutations of PIGK:
Generating mutation plots.
Highly correlated genes for PIGK:
Showing top 20/1007 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PIGK | SEC22A | 0.77055 | 4 | 0 | 4 |
| PIGK | YY1 | 0.731414 | 4 | 0 | 3 |
| PIGK | FITM2 | 0.712428 | 4 | 0 | 3 |
| PIGK | AGL | 0.710832 | 4 | 0 | 3 |
| PIGK | VPS33A | 0.710318 | 3 | 0 | 3 |
| PIGK | THAP2 | 0.709193 | 3 | 0 | 3 |
| PIGK | TM4SF18 | 0.705503 | 4 | 0 | 4 |
| PIGK | ZNF322 | 0.696051 | 3 | 0 | 3 |
| PIGK | MAGOHB | 0.694329 | 4 | 0 | 3 |
| PIGK | SCO1 | 0.692329 | 4 | 0 | 3 |
| PIGK | APH1B | 0.691747 | 5 | 0 | 5 |
| PIGK | CNTLN | 0.690182 | 3 | 0 | 3 |
| PIGK | ZDHHC16 | 0.684503 | 4 | 0 | 4 |
| PIGK | TEX261 | 0.683543 | 4 | 0 | 4 |
| PIGK | L3MBTL3 | 0.679808 | 3 | 0 | 3 |
| PIGK | FARSA | 0.679652 | 3 | 0 | 3 |
| PIGK | TGFBR1 | 0.679217 | 5 | 0 | 4 |
| PIGK | SLC30A7 | 0.678287 | 4 | 0 | 3 |
| PIGK | ERCC8 | 0.675511 | 5 | 0 | 3 |
| PIGK | CMPK2 | 0.674419 | 4 | 0 | 3 |
For details and further investigation, click here
