| Full name: NECAP endocytosis associated 2 | Alias Symbol: FLJ10420 | ||
| Type: protein-coding gene | Cytoband: 1p36.13 | ||
| Entrez ID: 55707 | HGNC ID: HGNC:25528 | Ensembl Gene: ENSG00000157191 | OMIM ID: 611624 |
| Drug and gene relationship at DGIdb | |||
Expression of NECAP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NECAP2 | 55707 | 220731_s_at | 0.3215 | 0.4941 | |
| GSE20347 | NECAP2 | 55707 | 220731_s_at | -0.3242 | 0.0096 | |
| GSE23400 | NECAP2 | 55707 | 220731_s_at | -0.0639 | 0.3790 | |
| GSE26886 | NECAP2 | 55707 | 220731_s_at | -0.1600 | 0.4081 | |
| GSE29001 | NECAP2 | 55707 | 220731_s_at | -0.0526 | 0.7255 | |
| GSE38129 | NECAP2 | 55707 | 220731_s_at | -0.0655 | 0.6287 | |
| GSE45670 | NECAP2 | 55707 | 220731_s_at | 0.1071 | 0.5005 | |
| GSE53622 | NECAP2 | 55707 | 15874 | -0.0858 | 0.3332 | |
| GSE53624 | NECAP2 | 55707 | 15874 | -0.1354 | 0.0538 | |
| GSE63941 | NECAP2 | 55707 | 220731_s_at | -0.9175 | 0.0116 | |
| GSE77861 | NECAP2 | 55707 | 220731_s_at | -0.5570 | 0.0070 | |
| GSE97050 | NECAP2 | 55707 | A_23_P97296 | 0.3333 | 0.3630 | |
| SRP007169 | NECAP2 | 55707 | RNAseq | -1.1839 | 0.0102 | |
| SRP008496 | NECAP2 | 55707 | RNAseq | -1.1159 | 0.0000 | |
| SRP064894 | NECAP2 | 55707 | RNAseq | 0.2979 | 0.1071 | |
| SRP133303 | NECAP2 | 55707 | RNAseq | 0.0098 | 0.9577 | |
| SRP159526 | NECAP2 | 55707 | RNAseq | -0.4006 | 0.0023 | |
| SRP193095 | NECAP2 | 55707 | RNAseq | -0.2756 | 0.0001 | |
| SRP219564 | NECAP2 | 55707 | RNAseq | -0.0219 | 0.9419 | |
| TCGA | NECAP2 | 55707 | RNAseq | 0.0743 | 0.1429 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by NECAP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NECAP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NECAP2 | 55707 | 1 | 5 | 24 | |
| GSE20123 | NECAP2 | 55707 | 1 | 4 | 25 | |
| GSE43470 | NECAP2 | 55707 | 1 | 8 | 34 | |
| GSE46452 | NECAP2 | 55707 | 5 | 1 | 53 | |
| GSE47630 | NECAP2 | 55707 | 8 | 3 | 29 | |
| GSE54993 | NECAP2 | 55707 | 3 | 1 | 66 | |
| GSE54994 | NECAP2 | 55707 | 11 | 4 | 38 | |
| GSE60625 | NECAP2 | 55707 | 0 | 0 | 11 | |
| GSE74703 | NECAP2 | 55707 | 1 | 5 | 30 | |
| GSE74704 | NECAP2 | 55707 | 1 | 0 | 19 | |
| TCGA | NECAP2 | 55707 | 10 | 23 | 63 |
Total number of gains: 42; Total number of losses: 54; Total Number of normals: 392.
Somatic mutations of NECAP2:
Generating mutation plots.
Highly correlated genes for NECAP2:
Showing top 20/506 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NECAP2 | ANKRD44 | 0.808779 | 3 | 0 | 3 |
| NECAP2 | TM2D2 | 0.784102 | 3 | 0 | 3 |
| NECAP2 | CHMP2A | 0.774856 | 3 | 0 | 3 |
| NECAP2 | FITM2 | 0.74982 | 3 | 0 | 3 |
| NECAP2 | ZNF578 | 0.745769 | 3 | 0 | 3 |
| NECAP2 | ERCC6 | 0.742669 | 3 | 0 | 3 |
| NECAP2 | KDM2A | 0.741557 | 3 | 0 | 3 |
| NECAP2 | UBE2L3 | 0.732052 | 3 | 0 | 3 |
| NECAP2 | PUSL1 | 0.714149 | 4 | 0 | 4 |
| NECAP2 | SEC24D | 0.709634 | 3 | 0 | 3 |
| NECAP2 | LRRK2 | 0.703726 | 3 | 0 | 3 |
| NECAP2 | SPTLC3 | 0.703653 | 3 | 0 | 3 |
| NECAP2 | SKI | 0.702291 | 3 | 0 | 3 |
| NECAP2 | SUMO3 | 0.69611 | 3 | 0 | 3 |
| NECAP2 | DOK1 | 0.694318 | 3 | 0 | 3 |
| NECAP2 | PTPN23 | 0.692438 | 4 | 0 | 3 |
| NECAP2 | PSEN2 | 0.692003 | 3 | 0 | 3 |
| NECAP2 | PTRHD1 | 0.690583 | 4 | 0 | 4 |
| NECAP2 | VPS29 | 0.690498 | 3 | 0 | 3 |
| NECAP2 | ZNF441 | 0.687697 | 3 | 0 | 3 |
For details and further investigation, click here
