FKBP14

 

Full name: FKBP prolyl isomerase 14 Alias Symbol: FLJ20731|FKBP22
Type: protein-coding gene Cytoband: 7p14.3
Entrez ID: 55033 HGNC ID: HGNC:18625 Ensembl Gene: ENSG00000106080 OMIM ID: 614505
Drug and gene relationship at DGIdb

 

Expression of FKBP14:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 FKBP14 55033 230728_at 0.2502 0.7731
GSE20347 FKBP14 55033 219390_at 0.7800 0.0004
GSE23400 FKBP14 55033 219390_at 0.2882 0.0000
GSE26886 FKBP14 55033 230728_at 1.6007 0.0000
GSE29001 FKBP14 55033 219390_at 0.4360 0.1888
GSE38129 FKBP14 55033 219390_at 0.8176 0.0000
GSE45670 FKBP14 55033 230728_at 0.0820 0.7608
GSE53622 FKBP14 55033 18476 0.8310 0.0000
GSE53624 FKBP14 55033 156437 0.7721 0.0000
GSE63941 FKBP14 55033 219390_at -1.4242 0.1216
GSE77861 FKBP14 55033 230728_at 0.3096 0.1618
GSE97050 FKBP14 55033 A_23_P215341 0.5478 0.2481
SRP007169 FKBP14 55033 RNAseq 1.1773 0.0055
SRP008496 FKBP14 55033 RNAseq 1.7585 0.0000
SRP064894 FKBP14 55033 RNAseq 0.7718 0.0013
SRP133303 FKBP14 55033 RNAseq 0.9398 0.0000
SRP159526 FKBP14 55033 RNAseq 0.4056 0.0095
SRP193095 FKBP14 55033 RNAseq 0.7270 0.0000
SRP219564 FKBP14 55033 RNAseq 0.7465 0.1815
TCGA FKBP14 55033 RNAseq 0.1624 0.0935

Upregulated datasets: 3; Downregulated datasets: 0.  

 

Survival by FKBP14 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of FKBP14:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 FKBP14 55033 16 0 14
GSE20123 FKBP14 55033 16 0 14
GSE43470 FKBP14 55033 4 0 39
GSE46452 FKBP14 55033 11 1 47
GSE47630 FKBP14 55033 8 1 31
GSE54993 FKBP14 55033 0 6 64
GSE54994 FKBP14 55033 19 3 31
GSE60625 FKBP14 55033 0 0 11
GSE74703 FKBP14 55033 4 0 32
GSE74704 FKBP14 55033 10 0 10
TCGA FKBP14 55033 55 6 35

Total number of gains: 143; Total number of losses: 17; Total Number of normals: 328.  

 

Somatic mutations of FKBP14:

 

Generating mutation plots.

 

Highly correlated genes for FKBP14:

 

Showing top 20/464 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
FKBP14SPRY4-IT10.691406303
FKBP14EID2B0.673857404
FKBP14SLC20A20.665983303
FKBP14AHR0.66479911010
FKBP14FCGR3A0.658923303
FKBP14SLC20A10.653812706
FKBP14CTHRC10.651323706
FKBP14LAMC20.65081311010
FKBP14ZNF2810.647795808
FKBP14CHRNA50.645981705
FKBP14BMP8B0.639565303
FKBP14KANK40.638709505
FKBP14CHSY10.6385971008
FKBP14PLEKHA80.635462604
FKBP14PROC0.634077504
FKBP14IKBIP0.632243706
FKBP14ELMSAN10.631958303
FKBP14BEND60.626893605
FKBP14TMEM2630.624463606
FKBP14TGFBI0.623771109

For details and further investigation, click here