ELMSAN1

 

Full name: ELM2 and Myb/SANT domain containing 1 Alias Symbol: LSR68
Type: protein-coding gene Cytoband: 14q24.3
Entrez ID: 91748 HGNC ID: HGNC:19853 Ensembl Gene: ENSG00000156030 OMIM ID: 
Drug and gene relationship at DGIdb
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of ELMSAN1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ELMSAN1 91748 225980_at 0.0928 0.8348
GSE26886 ELMSAN1 91748 225980_at 0.4905 0.0006
GSE45670 ELMSAN1 91748 225980_at 0.0273 0.8927
GSE53622 ELMSAN1 91748 16500 -0.1297 0.1226
GSE53624 ELMSAN1 91748 16500 -0.0670 0.3484
GSE63941 ELMSAN1 91748 225980_at 0.3438 0.2821
GSE77861 ELMSAN1 91748 225980_at 0.3539 0.3283
SRP007169 ELMSAN1 91748 RNAseq 0.8574 0.0687
SRP008496 ELMSAN1 91748 RNAseq 1.0681 0.0002
SRP064894 ELMSAN1 91748 RNAseq -0.2437 0.4684
SRP133303 ELMSAN1 91748 RNAseq 0.0214 0.9041
SRP159526 ELMSAN1 91748 RNAseq -0.2357 0.2505
SRP193095 ELMSAN1 91748 RNAseq 0.3953 0.0035
SRP219564 ELMSAN1 91748 RNAseq -0.0323 0.9273

Upregulated datasets: 1; Downregulated datasets: 0.  


 

Survival by ELMSAN1 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  


Copy number change of ELMSAN1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ELMSAN1 91748 8 2 20
GSE20123 ELMSAN1 91748 8 2 20
GSE43470 ELMSAN1 91748 8 3 32
GSE46452 ELMSAN1 91748 16 3 40
GSE47630 ELMSAN1 91748 11 8 21
GSE54993 ELMSAN1 91748 3 8 59
GSE54994 ELMSAN1 91748 18 4 31
GSE60625 ELMSAN1 91748 0 2 9
GSE74703 ELMSAN1 91748 7 3 26
GSE74704 ELMSAN1 91748 3 2 15
TCGA ELMSAN1 91748 31 16 49

Total number of gains: 113; Total number of losses: 53; Total Number of normals: 322.  


 

Somatic mutations of ELMSAN1:

 

Generating mutation plots.

 

Highly correlated genes for ELMSAN1:

 

Showing top 20/86 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ELMSAN1TNFRSF12A0.664039404
ELMSAN1ITPK10.658072403
ELMSAN1AUP10.655457303
ELMSAN1CARD100.649622404
ELMSAN1FKBP140.631958303
ELMSAN1FAF20.631333303
ELMSAN1FSTL30.629501403
ELMSAN1CBLB0.614912303
ELMSAN1ZNF5580.613943303
ELMSAN1ZNF1140.609832505
ELMSAN1KLF100.602148403
ELMSAN1TTLL50.601708504
ELMSAN1TTC80.600829605
ELMSAN1CPT1A0.598221303
ELMSAN1FTO0.594432403
ELMSAN1TECPR20.593411404
ELMSAN1ZNF354A0.592903303
ELMSAN1EGFR0.590183403
ELMSAN1LPAR30.589954403
ELMSAN1PTPN120.589508403

For details and further investigation, click here