| Full name: fibronectin leucine rich transmembrane protein 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 20p12.1 | ||
| Entrez ID: 23767 | HGNC ID: HGNC:3762 | Ensembl Gene: ENSG00000125848 | OMIM ID: 604808 |
| Drug and gene relationship at DGIdb | |||
Expression of FLRT3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FLRT3 | 23767 | 222853_at | 0.1932 | 0.9478 | |
| GSE20347 | FLRT3 | 23767 | 219250_s_at | 0.4514 | 0.1673 | |
| GSE23400 | FLRT3 | 23767 | 219250_s_at | 0.4967 | 0.0001 | |
| GSE26886 | FLRT3 | 23767 | 222853_at | 1.9612 | 0.0092 | |
| GSE29001 | FLRT3 | 23767 | 219250_s_at | 0.4024 | 0.5788 | |
| GSE38129 | FLRT3 | 23767 | 219250_s_at | 0.3205 | 0.3226 | |
| GSE45670 | FLRT3 | 23767 | 222853_at | 1.0181 | 0.0920 | |
| GSE53622 | FLRT3 | 23767 | 61754 | -0.0970 | 0.7577 | |
| GSE53624 | FLRT3 | 23767 | 61754 | 0.1502 | 0.5606 | |
| GSE63941 | FLRT3 | 23767 | 222853_at | -1.9670 | 0.1725 | |
| GSE77861 | FLRT3 | 23767 | 219250_s_at | 0.5717 | 0.1012 | |
| GSE97050 | FLRT3 | 23767 | A_33_P3418833 | -0.8579 | 0.1417 | |
| SRP007169 | FLRT3 | 23767 | RNAseq | 0.0696 | 0.8707 | |
| SRP008496 | FLRT3 | 23767 | RNAseq | 0.2959 | 0.5352 | |
| SRP064894 | FLRT3 | 23767 | RNAseq | 1.7511 | 0.0006 | |
| SRP133303 | FLRT3 | 23767 | RNAseq | 1.0479 | 0.0460 | |
| SRP159526 | FLRT3 | 23767 | RNAseq | -0.2188 | 0.7438 | |
| SRP193095 | FLRT3 | 23767 | RNAseq | 0.2117 | 0.5317 | |
| SRP219564 | FLRT3 | 23767 | RNAseq | 1.1078 | 0.0855 | |
| TCGA | FLRT3 | 23767 | RNAseq | -0.5291 | 0.1047 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by FLRT3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FLRT3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FLRT3 | 23767 | 9 | 1 | 20 | |
| GSE20123 | FLRT3 | 23767 | 9 | 1 | 20 | |
| GSE43470 | FLRT3 | 23767 | 11 | 1 | 31 | |
| GSE46452 | FLRT3 | 23767 | 26 | 1 | 32 | |
| GSE47630 | FLRT3 | 23767 | 18 | 4 | 18 | |
| GSE54993 | FLRT3 | 23767 | 0 | 14 | 56 | |
| GSE54994 | FLRT3 | 23767 | 25 | 1 | 27 | |
| GSE60625 | FLRT3 | 23767 | 0 | 0 | 11 | |
| GSE74703 | FLRT3 | 23767 | 8 | 1 | 27 | |
| GSE74704 | FLRT3 | 23767 | 4 | 1 | 15 | |
| TCGA | FLRT3 | 23767 | 42 | 11 | 43 |
Total number of gains: 152; Total number of losses: 36; Total Number of normals: 300.
Somatic mutations of FLRT3:
Generating mutation plots.
Highly correlated genes for FLRT3:
Showing top 20/157 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FLRT3 | FAM126A | 0.747487 | 3 | 0 | 3 |
| FLRT3 | TTC8 | 0.726706 | 3 | 0 | 3 |
| FLRT3 | SMTN | 0.721969 | 3 | 0 | 3 |
| FLRT3 | USP40 | 0.704167 | 3 | 0 | 3 |
| FLRT3 | POU6F2-AS2 | 0.697647 | 3 | 0 | 3 |
| FLRT3 | TWIST2 | 0.682344 | 4 | 0 | 3 |
| FLRT3 | TENM2 | 0.673489 | 4 | 0 | 4 |
| FLRT3 | STIM2 | 0.66777 | 3 | 0 | 3 |
| FLRT3 | C14orf119 | 0.657032 | 3 | 0 | 3 |
| FLRT3 | PDE7A | 0.65505 | 3 | 0 | 3 |
| FLRT3 | LIN52 | 0.651281 | 4 | 0 | 3 |
| FLRT3 | GPX8 | 0.650204 | 4 | 0 | 3 |
| FLRT3 | SUMF2 | 0.648251 | 4 | 0 | 3 |
| FLRT3 | IL31RA | 0.646947 | 4 | 0 | 4 |
| FLRT3 | L3HYPDH | 0.640722 | 4 | 0 | 3 |
| FLRT3 | ZFP90 | 0.6392 | 3 | 0 | 3 |
| FLRT3 | SMIM3 | 0.638592 | 3 | 0 | 3 |
| FLRT3 | RDH11 | 0.623696 | 5 | 0 | 4 |
| FLRT3 | CDH13 | 0.62152 | 6 | 0 | 4 |
| FLRT3 | C6orf141 | 0.615706 | 5 | 0 | 3 |
For details and further investigation, click here
