SMIM3

 

Full name: small integral membrane protein 3 Alias Symbol: MSTP150|NID67
Type: protein-coding gene Cytoband: 5q33.1
Entrez ID: 85027 HGNC ID: HGNC:30248 Ensembl Gene: ENSG00000256235 OMIM ID: 608324
Drug and gene relationship at DGIdb

 

Expression of SMIM3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SMIM3 85027 223276_at -0.0009 0.9994
GSE26886 SMIM3 85027 223276_at 1.5419 0.0003
GSE45670 SMIM3 85027 223276_at 0.3129 0.5068
GSE53622 SMIM3 85027 96268 0.7262 0.0000
GSE53624 SMIM3 85027 96268 0.9029 0.0000
GSE63941 SMIM3 85027 223276_at -1.9608 0.0133
GSE77861 SMIM3 85027 223276_at 0.5384 0.2815
SRP007169 SMIM3 85027 RNAseq 1.7440 0.0057
SRP008496 SMIM3 85027 RNAseq 1.6019 0.0002
SRP064894 SMIM3 85027 RNAseq 0.9954 0.0005
SRP133303 SMIM3 85027 RNAseq 1.2983 0.0044
SRP159526 SMIM3 85027 RNAseq -0.1635 0.6167
SRP193095 SMIM3 85027 RNAseq 0.7419 0.0013
SRP219564 SMIM3 85027 RNAseq 0.6545 0.0981

Upregulated datasets: 4; Downregulated datasets: 1.  


 

Survival by SMIM3 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  


Copy number change of SMIM3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SMIM3 85027 1 12 17
GSE20123 SMIM3 85027 1 12 17
GSE43470 SMIM3 85027 1 10 32
GSE46452 SMIM3 85027 0 27 32
GSE47630 SMIM3 85027 0 20 20
GSE54993 SMIM3 85027 9 2 59
GSE54994 SMIM3 85027 4 14 35
GSE60625 SMIM3 85027 0 0 11
GSE74703 SMIM3 85027 1 7 28
GSE74704 SMIM3 85027 1 7 12
TCGA SMIM3 85027 5 37 54

Total number of gains: 23; Total number of losses: 148; Total Number of normals: 317.  


 

Somatic mutations of SMIM3:

 

Generating mutation plots.

 

Highly correlated genes for SMIM3:

 

Showing top 20/450 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SMIM3HSD17B20.740383303
SMIM3HCFC1R10.72447303
SMIM3KLF100.71595404
SMIM3CSGALNACT20.712495707
SMIM3PLA2G150.699627303
SMIM3NID20.699153404
SMIM3LHFPL20.692965707
SMIM3COL6A30.677878606
SMIM3SERPINE10.674924706
SMIM3TBX20.674455303
SMIM3PDGFRB0.673183505
SMIM3PPP1R180.671539605
SMIM3AP5S10.667301303
SMIM3PMEPA10.664955605
SMIM3OLFML2B0.661385606
SMIM3FBLIM10.660783505
SMIM3MSN0.659074606
SMIM3KLF70.657623707
SMIM3DSE0.657604505
SMIM3STX1A0.656164303

For details and further investigation, click here