| Full name: fibromodulin | Alias Symbol: SLRR2E | ||
| Type: protein-coding gene | Cytoband: 1q32.1 | ||
| Entrez ID: 2331 | HGNC ID: HGNC:3774 | Ensembl Gene: ENSG00000122176 | OMIM ID: 600245 |
| Drug and gene relationship at DGIdb | |||
Expression of FMOD:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FMOD | 2331 | 202709_at | -0.0346 | 0.9714 | |
| GSE20347 | FMOD | 2331 | 202709_at | 0.4004 | 0.0036 | |
| GSE23400 | FMOD | 2331 | 202709_at | 0.1346 | 0.1057 | |
| GSE26886 | FMOD | 2331 | 202709_at | 1.1340 | 0.0088 | |
| GSE29001 | FMOD | 2331 | 202709_at | 0.3586 | 0.1497 | |
| GSE38129 | FMOD | 2331 | 202709_at | 0.0438 | 0.8822 | |
| GSE45670 | FMOD | 2331 | 202709_at | -0.6690 | 0.0442 | |
| GSE53622 | FMOD | 2331 | 14586 | 0.2122 | 0.2067 | |
| GSE53624 | FMOD | 2331 | 14586 | 0.5045 | 0.0034 | |
| GSE63941 | FMOD | 2331 | 202709_at | -3.3364 | 0.0000 | |
| GSE77861 | FMOD | 2331 | 202709_at | 0.5118 | 0.0122 | |
| GSE97050 | FMOD | 2331 | A_23_P114883 | 0.5913 | 0.1845 | |
| SRP007169 | FMOD | 2331 | RNAseq | 3.2720 | 0.0000 | |
| SRP008496 | FMOD | 2331 | RNAseq | 3.9398 | 0.0000 | |
| SRP064894 | FMOD | 2331 | RNAseq | 1.0222 | 0.0125 | |
| SRP133303 | FMOD | 2331 | RNAseq | 0.0482 | 0.8951 | |
| SRP159526 | FMOD | 2331 | RNAseq | 0.6476 | 0.0591 | |
| SRP193095 | FMOD | 2331 | RNAseq | 0.3616 | 0.4748 | |
| SRP219564 | FMOD | 2331 | RNAseq | 1.3043 | 0.0432 | |
| TCGA | FMOD | 2331 | RNAseq | -0.6502 | 0.0000 |
Upregulated datasets: 5; Downregulated datasets: 1.
Survival by FMOD expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FMOD:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FMOD | 2331 | 11 | 0 | 19 | |
| GSE20123 | FMOD | 2331 | 11 | 0 | 19 | |
| GSE43470 | FMOD | 2331 | 6 | 0 | 37 | |
| GSE46452 | FMOD | 2331 | 3 | 1 | 55 | |
| GSE47630 | FMOD | 2331 | 14 | 0 | 26 | |
| GSE54993 | FMOD | 2331 | 0 | 6 | 64 | |
| GSE54994 | FMOD | 2331 | 15 | 0 | 38 | |
| GSE60625 | FMOD | 2331 | 0 | 0 | 11 | |
| GSE74703 | FMOD | 2331 | 6 | 0 | 30 | |
| GSE74704 | FMOD | 2331 | 5 | 0 | 15 | |
| TCGA | FMOD | 2331 | 44 | 4 | 48 |
Total number of gains: 115; Total number of losses: 11; Total Number of normals: 362.
Somatic mutations of FMOD:
Generating mutation plots.
Highly correlated genes for FMOD:
Showing top 20/1005 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FMOD | ANGPTL2 | 0.766881 | 11 | 0 | 11 |
| FMOD | PDGFRB | 0.748105 | 12 | 0 | 11 |
| FMOD | FBLIM1 | 0.740243 | 3 | 0 | 3 |
| FMOD | CXCL5 | 0.737801 | 5 | 0 | 5 |
| FMOD | PXK | 0.734914 | 4 | 0 | 4 |
| FMOD | TBL2 | 0.731758 | 3 | 0 | 3 |
| FMOD | RAB11FIP5 | 0.727193 | 3 | 0 | 3 |
| FMOD | CTSK | 0.723912 | 13 | 0 | 12 |
| FMOD | MMP2 | 0.72314 | 11 | 0 | 11 |
| FMOD | TP53I13 | 0.719476 | 3 | 0 | 3 |
| FMOD | RFTN2 | 0.713861 | 3 | 0 | 3 |
| FMOD | PCOLCE | 0.713721 | 13 | 0 | 12 |
| FMOD | ALPK2 | 0.712365 | 3 | 0 | 3 |
| FMOD | PIGS | 0.711484 | 3 | 0 | 3 |
| FMOD | DNM3OS | 0.711333 | 4 | 0 | 3 |
| FMOD | CREB3L1 | 0.711072 | 11 | 0 | 10 |
| FMOD | CERS5 | 0.708179 | 3 | 0 | 3 |
| FMOD | FBN1 | 0.701607 | 11 | 0 | 11 |
| FMOD | GNG2 | 0.696651 | 4 | 0 | 4 |
| FMOD | ELF4 | 0.69398 | 4 | 0 | 3 |
For details and further investigation, click here
