| Full name: forkhead box D3 | Alias Symbol: Genesis|HFH2 | ||
| Type: protein-coding gene | Cytoband: 1p31.3 | ||
| Entrez ID: 27022 | HGNC ID: HGNC:3804 | Ensembl Gene: ENSG00000187140 | OMIM ID: 611539 |
| Drug and gene relationship at DGIdb | |||
Expression of FOXD3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FOXD3 | 27022 | 241609_at | 0.0358 | 0.9174 | |
| GSE20347 | FOXD3 | 27022 | 208500_x_at | -0.0599 | 0.2193 | |
| GSE23400 | FOXD3 | 27022 | 208500_x_at | -0.1097 | 0.0002 | |
| GSE26886 | FOXD3 | 27022 | 241609_at | 0.5006 | 0.0004 | |
| GSE29001 | FOXD3 | 27022 | 208500_x_at | -0.1649 | 0.0563 | |
| GSE38129 | FOXD3 | 27022 | 208500_x_at | -0.0357 | 0.4248 | |
| GSE45670 | FOXD3 | 27022 | 241609_at | 0.0830 | 0.4602 | |
| GSE53622 | FOXD3 | 27022 | 122444 | -0.4630 | 0.1284 | |
| GSE53624 | FOXD3 | 27022 | 122444 | -0.0655 | 0.7845 | |
| GSE63941 | FOXD3 | 27022 | 241612_at | 0.3286 | 0.3155 | |
| GSE77861 | FOXD3 | 27022 | 241609_at | -0.0025 | 0.9887 | |
| SRP159526 | FOXD3 | 27022 | RNAseq | 3.0677 | 0.0001 | |
| SRP219564 | FOXD3 | 27022 | RNAseq | 0.6573 | 0.5281 | |
| TCGA | FOXD3 | 27022 | RNAseq | 0.5546 | 0.1703 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by FOXD3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FOXD3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FOXD3 | 27022 | 3 | 6 | 21 | |
| GSE20123 | FOXD3 | 27022 | 3 | 5 | 22 | |
| GSE43470 | FOXD3 | 27022 | 5 | 4 | 34 | |
| GSE46452 | FOXD3 | 27022 | 1 | 1 | 57 | |
| GSE47630 | FOXD3 | 27022 | 8 | 5 | 27 | |
| GSE54993 | FOXD3 | 27022 | 0 | 0 | 70 | |
| GSE54994 | FOXD3 | 27022 | 6 | 4 | 43 | |
| GSE60625 | FOXD3 | 27022 | 0 | 0 | 11 | |
| GSE74703 | FOXD3 | 27022 | 4 | 3 | 29 | |
| GSE74704 | FOXD3 | 27022 | 2 | 2 | 16 | |
| TCGA | FOXD3 | 27022 | 10 | 20 | 66 |
Total number of gains: 42; Total number of losses: 50; Total Number of normals: 396.
Somatic mutations of FOXD3:
Generating mutation plots.
Highly correlated genes for FOXD3:
Showing top 20/241 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FOXD3 | S1PR2 | 0.676281 | 3 | 0 | 3 |
| FOXD3 | C20orf141 | 0.649819 | 3 | 0 | 3 |
| FOXD3 | TP53TG5 | 0.644862 | 4 | 0 | 4 |
| FOXD3 | ART1 | 0.644586 | 3 | 0 | 3 |
| FOXD3 | GTPBP10 | 0.643209 | 3 | 0 | 3 |
| FOXD3 | IL17F | 0.641702 | 3 | 0 | 3 |
| FOXD3 | DPEP1 | 0.640559 | 3 | 0 | 3 |
| FOXD3 | GRAP | 0.637371 | 3 | 0 | 3 |
| FOXD3 | CHD5 | 0.63564 | 4 | 0 | 3 |
| FOXD3 | CHST13 | 0.634078 | 4 | 0 | 3 |
| FOXD3 | NSMF | 0.633443 | 4 | 0 | 4 |
| FOXD3 | EXTL1 | 0.631446 | 4 | 0 | 4 |
| FOXD3 | KCNG2 | 0.63039 | 3 | 0 | 3 |
| FOXD3 | DZIP1L | 0.627508 | 3 | 0 | 3 |
| FOXD3 | PGK2 | 0.627264 | 3 | 0 | 3 |
| FOXD3 | HDAC10 | 0.626263 | 4 | 0 | 3 |
| FOXD3 | CCL7 | 0.623515 | 3 | 0 | 3 |
| FOXD3 | C9orf116 | 0.621713 | 5 | 0 | 5 |
| FOXD3 | JSRP1 | 0.620832 | 4 | 0 | 3 |
| FOXD3 | TFEB | 0.615264 | 4 | 0 | 3 |
For details and further investigation, click here
