| Full name: inositol monophosphatase 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 18p11.21 | ||
| Entrez ID: 3613 | HGNC ID: HGNC:6051 | Ensembl Gene: ENSG00000141401 | OMIM ID: 605922 |
| Drug and gene relationship at DGIdb | |||
Expression of IMPA2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IMPA2 | 3613 | 203126_at | 0.2086 | 0.8664 | |
| GSE20347 | IMPA2 | 3613 | 203126_at | -0.8339 | 0.0040 | |
| GSE23400 | IMPA2 | 3613 | 203126_at | -0.4039 | 0.0118 | |
| GSE26886 | IMPA2 | 3613 | 203126_at | -2.1305 | 0.0000 | |
| GSE29001 | IMPA2 | 3613 | 203126_at | -0.9478 | 0.0082 | |
| GSE38129 | IMPA2 | 3613 | 203126_at | -0.2970 | 0.4158 | |
| GSE45670 | IMPA2 | 3613 | 203126_at | -0.4542 | 0.0600 | |
| GSE53622 | IMPA2 | 3613 | 42098 | -0.9286 | 0.0000 | |
| GSE53624 | IMPA2 | 3613 | 42098 | -0.8594 | 0.0000 | |
| GSE63941 | IMPA2 | 3613 | 203126_at | 0.6909 | 0.3107 | |
| GSE77861 | IMPA2 | 3613 | 203126_at | -0.6136 | 0.0541 | |
| GSE97050 | IMPA2 | 3613 | A_23_P50081 | -0.3359 | 0.3650 | |
| SRP007169 | IMPA2 | 3613 | RNAseq | -1.8470 | 0.0000 | |
| SRP008496 | IMPA2 | 3613 | RNAseq | -1.6548 | 0.0000 | |
| SRP064894 | IMPA2 | 3613 | RNAseq | -0.6830 | 0.0310 | |
| SRP133303 | IMPA2 | 3613 | RNAseq | -0.8316 | 0.0067 | |
| SRP159526 | IMPA2 | 3613 | RNAseq | -0.3483 | 0.3490 | |
| SRP193095 | IMPA2 | 3613 | RNAseq | -0.7635 | 0.0002 | |
| SRP219564 | IMPA2 | 3613 | RNAseq | -1.0909 | 0.0581 | |
| TCGA | IMPA2 | 3613 | RNAseq | 0.0150 | 0.8675 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by IMPA2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IMPA2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IMPA2 | 3613 | 5 | 3 | 22 | |
| GSE20123 | IMPA2 | 3613 | 5 | 3 | 22 | |
| GSE43470 | IMPA2 | 3613 | 0 | 6 | 37 | |
| GSE46452 | IMPA2 | 3613 | 3 | 21 | 35 | |
| GSE47630 | IMPA2 | 3613 | 7 | 17 | 16 | |
| GSE54993 | IMPA2 | 3613 | 6 | 2 | 62 | |
| GSE54994 | IMPA2 | 3613 | 8 | 8 | 37 | |
| GSE60625 | IMPA2 | 3613 | 0 | 4 | 7 | |
| GSE74703 | IMPA2 | 3613 | 0 | 4 | 32 | |
| GSE74704 | IMPA2 | 3613 | 3 | 2 | 15 | |
| TCGA | IMPA2 | 3613 | 29 | 23 | 44 |
Total number of gains: 66; Total number of losses: 93; Total Number of normals: 329.
Somatic mutations of IMPA2:
Generating mutation plots.
Highly correlated genes for IMPA2:
Showing top 20/927 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IMPA2 | MAB21L3 | 0.742549 | 3 | 0 | 3 |
| IMPA2 | TP53RK | 0.741039 | 3 | 0 | 3 |
| IMPA2 | DEGS2 | 0.734782 | 4 | 0 | 4 |
| IMPA2 | DPY30 | 0.7289 | 3 | 0 | 3 |
| IMPA2 | C6orf132 | 0.720185 | 4 | 0 | 4 |
| IMPA2 | UGP2 | 0.713297 | 4 | 0 | 4 |
| IMPA2 | CAPNS2 | 0.711757 | 3 | 0 | 3 |
| IMPA2 | PRSS27 | 0.707384 | 4 | 0 | 4 |
| IMPA2 | ZDHHC21 | 0.704948 | 3 | 0 | 3 |
| IMPA2 | PXMP2 | 0.696836 | 4 | 0 | 4 |
| IMPA2 | S100A16 | 0.695629 | 5 | 0 | 4 |
| IMPA2 | CAPN14 | 0.695421 | 4 | 0 | 4 |
| IMPA2 | FBXL16 | 0.694756 | 5 | 0 | 5 |
| IMPA2 | GSKIP | 0.692973 | 4 | 0 | 4 |
| IMPA2 | MOB3C | 0.692216 | 3 | 0 | 3 |
| IMPA2 | ARF6 | 0.691292 | 7 | 0 | 7 |
| IMPA2 | ORMDL2 | 0.686295 | 7 | 0 | 6 |
| IMPA2 | SPINK7 | 0.684773 | 4 | 0 | 4 |
| IMPA2 | MPZL3 | 0.684469 | 5 | 0 | 4 |
| IMPA2 | FYTTD1 | 0.684367 | 4 | 0 | 3 |
For details and further investigation, click here
