| Full name: ATP binding cassette subfamily C member 5 | Alias Symbol: MRP5|SMRP|EST277145|MOAT-C | ||
| Type: protein-coding gene | Cytoband: 3q27.1 | ||
| Entrez ID: 10057 | HGNC ID: HGNC:56 | Ensembl Gene: ENSG00000114770 | OMIM ID: 605251 |
| Drug and gene relationship at DGIdb | |||
Expression of ABCC5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ABCC5 | 10057 | 209380_s_at | 0.6569 | 0.3020 | |
| GSE20347 | ABCC5 | 10057 | 209380_s_at | 1.5206 | 0.0000 | |
| GSE23400 | ABCC5 | 10057 | 209380_s_at | 0.9711 | 0.0000 | |
| GSE26886 | ABCC5 | 10057 | 209380_s_at | 0.5777 | 0.0749 | |
| GSE29001 | ABCC5 | 10057 | 209380_s_at | 0.7484 | 0.0647 | |
| GSE38129 | ABCC5 | 10057 | 209380_s_at | 1.3704 | 0.0000 | |
| GSE45670 | ABCC5 | 10057 | 209380_s_at | 1.4709 | 0.0004 | |
| GSE53622 | ABCC5 | 10057 | 7728 | 0.9479 | 0.0000 | |
| GSE53624 | ABCC5 | 10057 | 55917 | 1.0186 | 0.0000 | |
| GSE63941 | ABCC5 | 10057 | 209380_s_at | 1.2495 | 0.2195 | |
| GSE77861 | ABCC5 | 10057 | 209380_s_at | 1.5583 | 0.0070 | |
| GSE97050 | ABCC5 | 10057 | A_33_P3298057 | 0.6007 | 0.1897 | |
| SRP007169 | ABCC5 | 10057 | RNAseq | 3.1656 | 0.0000 | |
| SRP008496 | ABCC5 | 10057 | RNAseq | 2.7410 | 0.0000 | |
| SRP064894 | ABCC5 | 10057 | RNAseq | 0.9636 | 0.0002 | |
| SRP133303 | ABCC5 | 10057 | RNAseq | 1.0398 | 0.0002 | |
| SRP159526 | ABCC5 | 10057 | RNAseq | 2.2302 | 0.0001 | |
| SRP193095 | ABCC5 | 10057 | RNAseq | 1.1124 | 0.0000 | |
| SRP219564 | ABCC5 | 10057 | RNAseq | 0.7225 | 0.1316 | |
| TCGA | ABCC5 | 10057 | RNAseq | 0.0547 | 0.6062 |
Upregulated datasets: 10; Downregulated datasets: 0.
Survival by ABCC5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ABCC5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ABCC5 | 10057 | 25 | 0 | 5 | |
| GSE20123 | ABCC5 | 10057 | 25 | 0 | 5 | |
| GSE43470 | ABCC5 | 10057 | 24 | 0 | 19 | |
| GSE46452 | ABCC5 | 10057 | 19 | 1 | 39 | |
| GSE47630 | ABCC5 | 10057 | 27 | 2 | 11 | |
| GSE54993 | ABCC5 | 10057 | 1 | 19 | 50 | |
| GSE54994 | ABCC5 | 10057 | 41 | 0 | 12 | |
| GSE60625 | ABCC5 | 10057 | 0 | 6 | 5 | |
| GSE74703 | ABCC5 | 10057 | 20 | 0 | 16 | |
| GSE74704 | ABCC5 | 10057 | 17 | 0 | 3 | |
| TCGA | ABCC5 | 10057 | 77 | 0 | 19 |
Total number of gains: 276; Total number of losses: 28; Total Number of normals: 184.
Somatic mutations of ABCC5:
Generating mutation plots.
Highly correlated genes for ABCC5:
Showing top 20/747 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ABCC5 | RNF168 | 0.73165 | 7 | 0 | 7 |
| ABCC5 | COTL1 | 0.721844 | 3 | 0 | 3 |
| ABCC5 | LRRC58 | 0.699398 | 3 | 0 | 3 |
| ABCC5 | COMMD2 | 0.695718 | 3 | 0 | 3 |
| ABCC5 | EIF2B5 | 0.683691 | 10 | 0 | 9 |
| ABCC5 | KCNS3 | 0.678426 | 11 | 0 | 10 |
| ABCC5 | FOXQ1 | 0.674026 | 4 | 0 | 4 |
| ABCC5 | ECE2 | 0.668884 | 7 | 0 | 6 |
| ABCC5 | MAP4K1 | 0.667892 | 3 | 0 | 3 |
| ABCC5 | RASEF | 0.667299 | 4 | 0 | 4 |
| ABCC5 | PHTF1 | 0.662587 | 3 | 0 | 3 |
| ABCC5 | SOX2-OT | 0.661605 | 6 | 0 | 6 |
| ABCC5 | NIPA1 | 0.659722 | 4 | 0 | 3 |
| ABCC5 | C1orf131 | 0.655583 | 6 | 0 | 6 |
| ABCC5 | FOXE1 | 0.651387 | 13 | 0 | 12 |
| ABCC5 | PIGX | 0.650693 | 7 | 0 | 5 |
| ABCC5 | ABCA13 | 0.649807 | 7 | 0 | 5 |
| ABCC5 | RNF7 | 0.648988 | 10 | 0 | 9 |
| ABCC5 | TXNRD1 | 0.645248 | 11 | 0 | 9 |
| ABCC5 | ECT2 | 0.645096 | 10 | 0 | 8 |
For details and further investigation, click here
