| Full name: TNF superfamily member 15 | Alias Symbol: TL1|VEGI|TL1A|VEGI192A|MGC129934|MGC129935 | ||
| Type: protein-coding gene | Cytoband: 9q32 | ||
| Entrez ID: 9966 | HGNC ID: HGNC:11931 | Ensembl Gene: ENSG00000181634 | OMIM ID: 604052 |
| Drug and gene relationship at DGIdb | |||
Expression of TNFSF15:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TNFSF15 | 9966 | 229242_at | 0.4453 | 0.5102 | |
| GSE20347 | TNFSF15 | 9966 | 221085_at | -0.2110 | 0.4217 | |
| GSE23400 | TNFSF15 | 9966 | 221085_at | -0.0768 | 0.0235 | |
| GSE26886 | TNFSF15 | 9966 | 229242_at | -0.7221 | 0.1053 | |
| GSE29001 | TNFSF15 | 9966 | 221085_at | -0.2097 | 0.4643 | |
| GSE38129 | TNFSF15 | 9966 | 221085_at | -0.2032 | 0.3543 | |
| GSE45670 | TNFSF15 | 9966 | 229242_at | 0.0952 | 0.8030 | |
| GSE53622 | TNFSF15 | 9966 | 25685 | 0.1700 | 0.3301 | |
| GSE53624 | TNFSF15 | 9966 | 25685 | -0.3025 | 0.0608 | |
| GSE63941 | TNFSF15 | 9966 | 229242_at | 1.6244 | 0.1888 | |
| GSE77861 | TNFSF15 | 9966 | 229242_at | -0.2216 | 0.6128 | |
| GSE97050 | TNFSF15 | 9966 | A_23_P94754 | 0.4046 | 0.2074 | |
| SRP007169 | TNFSF15 | 9966 | RNAseq | -0.0864 | 0.8667 | |
| SRP064894 | TNFSF15 | 9966 | RNAseq | 0.0890 | 0.7482 | |
| SRP133303 | TNFSF15 | 9966 | RNAseq | -0.2174 | 0.3930 | |
| SRP159526 | TNFSF15 | 9966 | RNAseq | 0.0704 | 0.9189 | |
| SRP193095 | TNFSF15 | 9966 | RNAseq | -0.1864 | 0.2622 | |
| SRP219564 | TNFSF15 | 9966 | RNAseq | 0.7745 | 0.3176 | |
| TCGA | TNFSF15 | 9966 | RNAseq | -0.1616 | 0.5508 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TNFSF15 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TNFSF15:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TNFSF15 | 9966 | 5 | 10 | 15 | |
| GSE20123 | TNFSF15 | 9966 | 5 | 10 | 15 | |
| GSE43470 | TNFSF15 | 9966 | 4 | 3 | 36 | |
| GSE46452 | TNFSF15 | 9966 | 6 | 13 | 40 | |
| GSE47630 | TNFSF15 | 9966 | 3 | 16 | 21 | |
| GSE54993 | TNFSF15 | 9966 | 3 | 3 | 64 | |
| GSE54994 | TNFSF15 | 9966 | 9 | 10 | 34 | |
| GSE60625 | TNFSF15 | 9966 | 0 | 0 | 11 | |
| GSE74703 | TNFSF15 | 9966 | 4 | 3 | 29 | |
| GSE74704 | TNFSF15 | 9966 | 2 | 7 | 11 | |
| TCGA | TNFSF15 | 9966 | 27 | 21 | 48 |
Total number of gains: 68; Total number of losses: 96; Total Number of normals: 324.
Somatic mutations of TNFSF15:
Generating mutation plots.
Highly correlated genes for TNFSF15:
Showing top 20/198 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TNFSF15 | TMEM17 | 0.757667 | 3 | 0 | 3 |
| TNFSF15 | GNL3 | 0.750393 | 3 | 0 | 3 |
| TNFSF15 | HNRNPF | 0.736915 | 3 | 0 | 3 |
| TNFSF15 | SKP2 | 0.711147 | 4 | 0 | 4 |
| TNFSF15 | PIGX | 0.705349 | 3 | 0 | 3 |
| TNFSF15 | FOXQ1 | 0.6925 | 3 | 0 | 3 |
| TNFSF15 | BIRC3 | 0.688294 | 5 | 0 | 4 |
| TNFSF15 | POLH | 0.679799 | 4 | 0 | 3 |
| TNFSF15 | RAB4B | 0.672984 | 3 | 0 | 3 |
| TNFSF15 | ZDHHC16 | 0.670281 | 3 | 0 | 3 |
| TNFSF15 | CLCN5 | 0.664555 | 3 | 0 | 3 |
| TNFSF15 | LCMT2 | 0.664554 | 3 | 0 | 3 |
| TNFSF15 | MOB1A | 0.663449 | 4 | 0 | 4 |
| TNFSF15 | FBXO11 | 0.662933 | 4 | 0 | 3 |
| TNFSF15 | PPP2R1B | 0.661246 | 3 | 0 | 3 |
| TNFSF15 | RALGPS2 | 0.657634 | 3 | 0 | 3 |
| TNFSF15 | ZNF101 | 0.655204 | 3 | 0 | 3 |
| TNFSF15 | TAGAP | 0.654465 | 4 | 0 | 4 |
| TNFSF15 | TM7SF3 | 0.654353 | 3 | 0 | 3 |
| TNFSF15 | HLA-DPA1 | 0.653818 | 4 | 0 | 4 |
For details and further investigation, click here
